Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Michael T. Bowen"'
Autor:
Carol J. Milligan, Lyndsey L. Anderson, Michael T. Bowen, Samuel D. Banister, Iain S. McGregor, Jonathon C. Arnold, Steven Petrou
Publikováno v:
Journal of Cannabis Research, Vol 4, Iss 1, Pp 1-12 (2022)
Abstract Background Purified cannabidiol (CBD), a non-psychoactive phytocannabinoid, has gained regulatory approval to treat intractable childhood epilepsies. Despite this, artisanal and commercial CBD-dominant hemp-based products continue to be used
Externí odkaz:
https://doaj.org/article/58d1be1bbaa14277b5551605e16ab7e9
Autor:
Richard C. Kevin, Elizabeth A. Cairns, Rochelle Boyd, Jonathon C. Arnold, Michael T. Bowen, Iain S. McGregor, Samuel D. Banister
Publikováno v:
Frontiers in Psychiatry, Vol 13 (2022)
IntroductionSynthetic cannabinoid receptor agonists (SCRAs) are a diverse class of new psychoactive substances that have been associated with multiple instances and types of toxicity. Some SCRAs appear to carry a greater toxicological burden than oth
Externí odkaz:
https://doaj.org/article/cb337490244f4ed28431c959c2053eeb
Publikováno v:
Frontiers in Endocrinology, Vol 12 (2021)
Externí odkaz:
https://doaj.org/article/cedfc553ef944d618935389c1a0cdf7b
Publikováno v:
SLEEP.
Study Objectives Exogenous administration of the neuropeptide oxytocin exerts diverse effects on various neurobehavioral processes, including sleep and wakefulness. Since oxytocin can enhance attention to social and fear-related environmental cues, i
Autor:
Oliver Tan, Michael T. Bowen
Publikováno v:
Handbook of Anger, Aggression, and Violence ISBN: 9783030987114
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d390a1f1dc9e3b3bd727d81e598efefb
https://doi.org/10.1007/978-3-030-98711-4_90-1
https://doi.org/10.1007/978-3-030-98711-4_90-1
IntroductionExogenous administration of the neuropeptide oxytocin exerts diverse effects on various neurobehavioural processes, including sleep and wakefulness. Since oxytocin can enhance attention to social and fear-related environmental cues, it sh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4b1d13feda1a32bfc99c589ed15c6aa8
https://doi.org/10.1101/2022.11.23.514802
https://doi.org/10.1101/2022.11.23.514802
Autor:
Nicole A. Hawkins, Jonathon C. Arnold, Michael T. Bowen, Jennifer A. Kearney, Mary Chebib, Fan Zhang, Iain S. McGregor, Marika Heblinski, Dilara Bahceci, Lyndsey L. Anderson, Nathan L. Absalom, Melissa J. Benson, Peter T. Doohan
Publikováno v:
British Journal of Pharmacology. 178:4826-4841
Background and purpose Cannabis has been used to treat epilepsy for millennia, with such use validated by regulatory approval of cannabidiol (CBD) for the treatment of Dravet syndrome. Unregulated artisanal cannabis-based products used to treat child
Autor:
Michael T. Bowen, James R Krycer, Charlotte Fletcher, Lewis J. Martin, Jonathon C. Arnold, Marika Heblinski, Iain S. McGregor, Lyndsey L. Anderson, Elizabeth A. Cairns
Publikováno v:
Journal of Natural Products. 84:1469-1477
Cannabis sativa contains >120 phytocannabinoids, but our understanding of these compounds is limited. Determining the molecular modes of action of the phytocannabinoids may assist in their therapeutic development. Ligand-based virtual screening was u
Autor:
Lewis J. Martin, Michael T. Bowen
Publikováno v:
Journal of Chemical Information and Modeling. 60:4536-4545
Ligand-based virtual screening is a useful tool for drug and probe discovery due to its high accessibility and scalability. The recent identification of bias in many data sets that were used in performance evaluation, quantified by the asymmetric val
Publikováno v:
Journal of Psychopharmacology. 34:795-805
Background: 5-HT1A receptor (5-HT1AR) abnormalities are implicated in aggression, and there has been considerable interest in developing 5-HT1AR agonists for treating aggression. Endogenous oxytocin (OXT) released upon stimulation of 5-HT1ARs in the