Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Michael T Moran"'
Publikováno v:
PLoS ONE, Vol 8, Iss 11, p e80829 (2013)
BACKGROUND: Alzheimer's disease (AD) is a debilitating age related progressive neurodegenerative disorder characterized by the loss of cognition, and eventual death of the affected individual. One of the major causes of AD is the accumulation of Amyl
Externí odkaz:
https://doaj.org/article/eea9b750639e473eb23d2b6ddf3ab83b
Autor:
Nora Lakes, Laura M. Canaday, Dan H. Barouch, Durga Krishnamurthy, Jasmine A. Tuazon, Hilal Cevik, Eryn Blass, Sanjeeth Rajaram, Ayad Ali, H. Alex Feldman, Harsha Seelamneni, Michael T. Moran, Stephen N. Waggoner
Natural killer (NK) cell suppression of T cells is a key determinant of viral pathogenesis and vaccine efficacy. This process involves perforin-dependent elimination of activated CD4 T cells during the first three days of infection. Although this mec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::04defe3fb9013721355c758e628db61c
https://doi.org/10.1101/2021.05.11.443590
https://doi.org/10.1101/2021.05.11.443590
Autor:
Fazeela Yaqoob, Seth D. Reighard, Carolyn Rydyznski, Jonathan P McNally, Sarah E. Mahl, Taylor R. Brooks, Michael T. Moran, Stephen N. Waggoner, Stacey A. Cranert, Ivayla E. Gyurova, Erik P. Karmele
Publikováno v:
Current Opinion in Virology. 16:15-23
Natural killer (NK) cells are important in immune defense against virus infections. This is predominantly considered a function of rapid, innate NK-cell killing of virus-infected cells. However, NK cells also prime other immune cells through the rele
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b94fc21b5bc5bb39689872d6d47060e0
https://doi.org/10.1016/j.coviro.2015.10.008
https://doi.org/10.1016/j.coviro.2015.10.008
Publikováno v:
The Journal of Immunology. 204:95.10-95.10
Natural killer (NK) cells dictate the pathogenic outcomes of infection via both direct killing of virus-infected cells and indirect immunoregulatory killing of antiviral T cells. The latter involves a perforin-dependent mechanism targeting activated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9ad0ba773b7b2f4aec584be821c013d1
https://doi.org/10.4049/jimmunol.204.supp.95.10
https://doi.org/10.4049/jimmunol.204.supp.95.10
Publikováno v:
The Journal of Immunology. 204:95.1-95.1
Natural killer (NK) cells are critical for both direct control of virus replication and regulation of potentially pathogenic antiviral responses. Yet, whether NK cells also contribute to immune control of bacterial superinfections during viral infect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::394ae60416fe630eccfd85b0578843b2
https://doi.org/10.4049/jimmunol.204.supp.95.1
https://doi.org/10.4049/jimmunol.204.supp.95.1
Autor:
Ayad Ali, Michael T Moran, Jasmine Tuazon, Ivayla Gyurova, Dario AA Vignali, Stephen N Waggoner
Publikováno v:
The Journal of Immunology. 202:76.7-76.7
Natural killer (NK) cells suppress antiviral immunity by killing a fraction of virus-specific CD4 T cells. This occurs during the first 3 days of infection, is perforin-dependent, and coincides with NK-cell localization in the splenic white pulp. Whi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b31bb6e5b28a0ee2867d704d17acb8a5
https://doi.org/10.4049/jimmunol.202.supp.76.7
https://doi.org/10.4049/jimmunol.202.supp.76.7
Publikováno v:
genesis. 51:68-74
Genetic mosaic approach is commonly used in the Drosophila eye by completely abolishing or misexpressing a gene within a subset of cells to unravel its role during development. Classical genetic mosaic approach involves random clone generation in all
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59bf34e7b1e1be57ccbe4aa6783ddbba
https://doi.org/10.1002/dvg.22355
https://doi.org/10.1002/dvg.22355
Autor:
Greg Mancini, Oorvashi Roy Puli, Meghana Tare, Timothy Cutler, Michael T. Moran, Andrew M. Steffensmeier, Neha Gogia, Amit Singh, Ankita Sarkar
Publikováno v:
PLoS ONE, Vol 10, Iss 9, p e0137691 (2015)
PLoS ONE
PLoS ONE
Background The progressive neurodegenerative disorder Alzheimer’s disease (AD) manifests as loss of cognitive functions, and finally leads to death of the affected individual. AD may result from accumulation of amyloid plaques. These amyloid plaque
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a318e3314f87ad6c1c07e3d7c1566988
http://europepmc.org/articles/PMC4569556?pdf=render
http://europepmc.org/articles/PMC4569556?pdf=render
Publikováno v:
The Journal of Immunology. 196:147.9-147.9
Natural killer (NK) cells are cytotoxic innate lymphocytes that provide immune defense against pathogens and tumors, and act as potent regulators of adaptive immunity. Notably, NK cells inhibit humoral immunity by restricting the magnitude of follicu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8aab96734fd67a3fdaf50e250df0d105
https://doi.org/10.4049/jimmunol.196.supp.147.9
https://doi.org/10.4049/jimmunol.196.supp.147.9