Zobrazeno 1 - 10
of 537
pro vyhledávání: '"Michael T, Williams"'
Publikováno v:
Current Research in Toxicology, Vol 6, Iss , Pp 100151- (2024)
For decades, regulatory guidelines for safety assessment in rodents for drugs, chemicals, pesticides, and food additives with developmental neurotoxic potential have recommended a single test of learning and memory (L&M). In recent years some agencie
Externí odkaz:
https://doaj.org/article/7ac355a490c242fda1b4ede62f83f4dd
Autor:
Sandra P. Zoubovsky, Michael T. Williams, Sarah Hoseus, Shivani Tumukuntala, Amy Riesenberg, Jay Schulkin, Charles V. Vorhees, Kenneth Campbell, Hee-Woong Lim, Louis J. Muglia
Publikováno v:
Translational Psychiatry, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract Prenatal stress (PS) is associated with increased vulnerability to affective disorders. Transplacental glucocorticoid passage and stress-induced maternal environment alterations are recognized as potential routes of transmission that can fun
Externí odkaz:
https://doaj.org/article/8750925e45ce4ff2a86ab3b84a58e713
Autor:
Monica S. Carbajal, Asiah J. C. Bounmy, Olivia B. Harrison, Hunter G. Nolen, Samantha L. Regan, Michael T. Williams, Charles V. Vorhees, Helen J. K. Sable
Publikováno v:
Frontiers in Neuroscience, Vol 17 (2023)
IntroductionImpulsivity is a symptom of attention-deficit/hyperactivity disorder (ADHD) and variants in the Lphn3 (Adgrl3) gene (OMIM 616417) have been linked to ADHD. This project utilized a delay-discounting (DD) task to examine the impact of Lphn3
Externí odkaz:
https://doaj.org/article/d4f763654aa6468caf02c6c349489b24
Autor:
Cadierno, Victorio1
Publikováno v:
Angewandte Chemie. Jul2014, Vol. 126 Issue 29, p7526-7527. 2p.
Autor:
Victorio Cadierno
Publikováno v:
Angewandte Chemie. 126:7526-7527
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c4e6ef8628f5df4edeb3dce38588d1f6
https://doi.org/10.1002/ange.201402899
https://doi.org/10.1002/ange.201402899
Autor:
Victorio Cadierno
Publikováno v:
Angewandte Chemie International Edition. 53:7398-7399
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::42821f25fc93c4fa03a32f76929c69d7
https://doi.org/10.1002/anie.201402899
https://doi.org/10.1002/anie.201402899
Autor:
Michael T. Williams, Chiho Sugimoto, Samantha L. Regan, Emily M. Pitzer, Adam L. Fritz, Anthony E. Mascia, Mathieu Sertorio, Ralph E. Vatner, John P. Perentesis, Charles V. Vorhees
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-20 (2020)
Abstract Proton radiotherapy causes less off-target effects than X-rays but is not without effect. To reduce adverse effects of proton radiotherapy, a model of cognitive deficits from conventional proton exposure is needed. We developed a model empha
Externí odkaz:
https://doaj.org/article/5d32edd717014b9596a855396e69d6d1
Autor:
Emily M. Pitzer, Chiho Sugimoto, Samantha L. Regan, Gary A. Gudelsky, Michael T. Williams, Charles V. Vorhees
Publikováno v:
Current Research in Toxicology, Vol 3, Iss , Pp 100093- (2022)
Pyrethroid pesticides are widely used and can cause long-term effects after early exposure. Epidemiological and animal studies reveal associations between pyrethroid exposure and altered cognition following prenatal and/or neonatal exposure. However,
Externí odkaz:
https://doaj.org/article/082ff1bf5a4f4e23b7c453dc6e546d6b
Autor:
Michael T Williams, Chiho Sugimoto, Samantha L Regan, Emily M Pitzer, Adam L Fritz, Mathieu Sertorio, Anthony E Mascia, Ralph E Vatner, John P Perentesis, Charles V Vorhees
Publikováno v:
PLoS ONE, Vol 17, Iss 9, p e0274007 (2022)
Recent studies suggest that ultra-high dose rates of proton radiation (>40 Gy/s; FLASH) confer less toxicity to exposed healthy tissue and reduce cognitive decline compared with conventional radiation dose rates (~1 Gy/s), but further preclinical dat
Externí odkaz:
https://doaj.org/article/8cca211bfd4841748d9af0addd081e91
Autor:
Samantha L. Regan, Emily M. Pitzer, Jillian R. Hufgard, Chiho Sugimoto, Michael T. Williams, Charles V. Vorhees
Publikováno v:
Neurobiology of Disease, Vol 158, Iss , Pp 105456- (2021)
Latrophilins (LPHNs) are adhesion G protein-coupled receptors with three isoforms but only LPHN3 is brain specific (caudate, prefrontal cortex, dentate, amygdala, and cerebellum). Variants of LPHN3 are associated with ADHD. Null mutations of Lphn3 in
Externí odkaz:
https://doaj.org/article/02d801f1a8994218b16fd0930b543a3e