Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Michael T, Vu"'
Publikováno v:
PLoS ONE, Vol 13, Iss 2, p e0192125 (2018)
The following study was undertaken to investigate the effect of concussion and psychiatric illness on athletes and their caregivers.Semi-structured interviews with 20 ice hockey stakeholders (17 men and 3 women) including minor and professional playe
Externí odkaz:
https://doaj.org/article/f5f2136621bd4cedb164d4c43e270429
Autor:
Haiying Wu, Beverley A. Orser, Hattie Liu, Gaspard Montandon, Richard L. Horner, Michael T. Vu
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-13 (2017)
Persistent and stable respiratory activity across behavioral states is key to homeostasis. Extrasynaptic δ-subunit containing GABAA receptors (δGABAARs) mediate tonic inhibition and regulate network activity. However, the influence of δGABAARs on
Publikováno v:
The Journal of Neuroscience. 35:13555-13567
Basal forebrain cholinergic neurons are the main source of cortical acetylcholine, and their activation by histamine elicits cortical arousal. TWIK-like acid-sensitive K+(TASK) channels modulate neuronal excitability and are expressed on basal forebr
Autor:
Gaspard, Montandon, Haiying, Wu, Hattie, Liu, Michael T, Vu, Beverley A, Orser, Richard L, Horner
Publikováno v:
Scientific Reports
Persistent and stable respiratory activity across behavioral states is key to homeostasis. Extrasynaptic δ-subunit containing GABAA receptors (δGABAARs) mediate tonic inhibition and regulate network activity. However, the influence of δGABAARs on
Autor:
Stephen Cusack, Tommie L. Lincecum, Andrés Palencia, Michael T. Vu, Susan A. Martinis, Thibaut Crépin
Publikováno v:
Nature structural & molecular biology
Leucyl-tRNA synthetase (LeuRS) produces error free leucyl-tRNALeu by coordinating translocation of the 3′ end of (mis-)charged tRNAs from its synthetic site to a separate proof-reading site for editing. Here we report co-crystal structures of the E
Autor:
Peng Zhai, Cecilia Guerra, Shirley Liu, Michael T. Vu, Jonathan J. Silberg, Michael C. Gustin, Juhye M. Lee
Publikováno v:
Protein Science. 21:258-267
Human mitochondrial DNLZ/HEP regulates the catalytic activity and solubility of the mitochondrial hsp70 chaperone HSPA9. Here, we investigate the role that the DNLZ zinc-binding and C-terminal subdomains play in regulating HSPA9. We show that truncat
Publikováno v:
PLoS ONE
PLoS ONE, Vol 13, Iss 2, p e0192125 (2018)
PLoS ONE, Vol 13, Iss 2, p e0192125 (2018)
Objective The following study was undertaken to investigate the effect of concussion and psychiatric illness on athletes and their caregivers. Methods Semi-structured interviews with 20 ice hockey stakeholders (17 men and 3 women) including minor and
Publikováno v:
Proceedings of the National Academy of Sciences. 105:19223-19228
Mistranslation is toxic to bacterial and mammalian cells and can lead to neurodegeneration in the mouse. Mistranslation is caused by the attachment of the wrong amino acid to a specific tRNA. Many aminoacyl-tRNA synthetases have an editing activity t
Autor:
Michael T. Vu, Susan A. Martinis
Publikováno v:
Biochemistry. 46:5170-5176
Leucyl-tRNA synthetase (LeuRS) is a class I enzyme, which houses its aminoacylation active site in a canonical core that is defined by a Rossmann nucleotide binding fold. In addition, many LeuRSs bear a unique polypeptide insert comprised of about 50