Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Michael T, Marr"'
Autor:
Meghan T. Harris, Michael T. Marr, II
Publikováno v:
Cell Reports, Vol 42, Iss 10, Pp 113283- (2023)
Summary: Cells activate stress response pathways to survive adverse conditions. Such responses involve the inhibition of global cap-dependent translation. This inhibition is a block that essential transcripts must escape via alternative methods of tr
Externí odkaz:
https://doaj.org/article/5726737a4edd48c5809ab79f7451ebc6
Autor:
Joyce Rigal, Ane Martin Anduaga, Elena Bitman, Emma Rivellese, Sebastian Kadener, Michael T Marr
Publikováno v:
eLife, Vol 11 (2022)
Transposable elements (TEs) are mobile sequences of DNA that can become transcriptionally active as an animal ages. Whether TE activity is simply a by-product of heterochromatin breakdown or can contribute toward the aging process is not known. Here,
Externí odkaz:
https://doaj.org/article/8d48da48f31641aebd03255696b5b0c6
Autor:
Deepika Vasudevan, Nicholas K. Clark, Jessica Sam, Victoria C. Cotham, Beatrix Ueberheide, Michael T. Marr, II, Hyung Don Ryoo
Publikováno v:
Cell Reports, Vol 21, Iss 8, Pp 2039-2047 (2017)
Bacterial infection often leads to suppression of mRNA translation, but hosts are nonetheless able to express immune response genes through as yet unknown mechanisms. Here, we use a Drosophila model to demonstrate that antimicrobial peptide (AMP) pro
Externí odkaz:
https://doaj.org/article/363f9690a191425680331fa8254dcb71
Autor:
Siobhan Gartland, Michael T. Marr
Aging can be defined as the progressive loss of physiological homeostasis that leads to a decline in cellular and organismal function. In recent years, it has become clear that small RNA pathways play a role in aging and aging related phenotypes. Sma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f277e31e54ce313c95378b8ff4bb8509
https://doi.org/10.1101/2022.08.12.503791
https://doi.org/10.1101/2022.08.12.503791
Protein synthesis is tightly regulated under stress conditions where energy may be scarce. Despite global repression of translation, some transcripts remain actively translated in order for the cell to be able to respond to the insult or prepare to q
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::20a3fcb4252449d10a5eec90b022c8f1
https://doi.org/10.1101/2022.07.26.501659
https://doi.org/10.1101/2022.07.26.501659
Publikováno v:
SSRN Electronic Journal.
Publikováno v:
eLife, Vol 2 (2013)
Under conditions of stress, such as limited growth factor signaling, translation is inhibited by the action of 4E-BP and PDCD4. These proteins, through inhibition of eIF4E and eIF4A, respectively, impair cap-dependent translation. Under stress condit
Externí odkaz:
https://doaj.org/article/609297efddf443b2bc2c6941f9bb89c4
Autor:
Victor Kubatin, Michael T. Marr, Meghan T Harris, Tereasa Ching Ho, Lingyan Xue, Harry Fruchtman, Mira E. Garin, Tiger Lu
Publikováno v:
Microbiology Resource Announcements
Vibrio natriegens, a fast-growing Gram-negative bacterium, is gaining interest as a platform for rapid biotechnology applications and metabolic engineering. Only a few bacteriophages that infect this bacterium have been identified. Here, we describe
Publikováno v:
Molecular and Cellular Neuroscience. 85:190-201
The central nervous system has the remarkable ability to convert changes in the environment in the form of sensory experience into long-term alterations in synaptic connections and dendritic arborization, in part through changes in gene expression. S