Zobrazeno 1 - 10
of 1 385
pro vyhledávání: '"Michael T, Bardo"'
Autor:
Jakob D. Shaykin, Lidia N. Olyha, Catherine E. Van Doorn, Joshua D. Hales, Cassie M. Chandler, Deann M. Hopkins, Kimberly Nixon, Joshua S. Beckmann, James R. Pauly, Michael T. Bardo
Publikováno v:
Drug and Alcohol Dependence Reports, Vol 12, Iss , Pp 100277- (2024)
Background: Alcohol use in adolescence may increase susceptibility to substance use disorders (SUDs) in adulthood. This study determined if voluntary ethanol (EtOH) consumption during adolescence, combined with social isolation, alters the trajectory
Externí odkaz:
https://doaj.org/article/e6cd4af6c9a849c3b547ab97e4c98949
Autor:
Navid S. Tavakoli, Samantha G. Malone, Tanner L. Anderson, Ryson E. Neeley, Artin Asadipooya, Michael T. Bardo, Pavel I. Ortinski
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 18 (2024)
Recent literature supports a prominent role for astrocytes in regulation of drug-seeking behaviors. The dorsal striatum, specifically, is known to play a role in reward processing with neuronal activity that can be influenced by astrocyte Ca2+. Howev
Externí odkaz:
https://doaj.org/article/ebc9ab46bd814c30abe0b689479360f2
Autor:
Jessica I. Wooden, Lauren E. Peacoe, Chinchusha Anasooya Shaji, Jennifer K. Melbourne, Cassie M. Chandler, Michael T. Bardo, Kimberly Nixon
Publikováno v:
Cells, Vol 12, Iss 21, p 2572 (2023)
During adolescence, the brain is highly susceptible to alcohol-induced damage and subsequent neuroimmune responses, effects which may enhance development of an alcohol use disorder (AUD). Neuroimmune reactions are implicated in adolescent alcohol exp
Externí odkaz:
https://doaj.org/article/59e18004e79a4d4590e0c0ac61e66216
Publikováno v:
Psychopharmacology. 240:295-301
Autor:
Cassie M, Chandler, Jakob D, Shaykin, Hui, Peng, James R, Pauly, Kimberly, Nixon, Michael T, Bardo
Publikováno v:
Alcohol. 104:13-21
Initiating alcohol use in adolescence significantly increases the likelihood of developing adult alcohol use disorder (AUD). However, it has been difficult to replicate adolescent alcohol exposure leading to increased adult alcohol intake across diff
Autor:
Lindsey R. Hammerslag, Bree A. Humburg, Samantha G. Malone, Joshua S. Beckmann, Kathryn E. Saatman, Valery Grinevich, Michael T. Bardo
Publikováno v:
Addiction Biology. 27
The purpose of this study was to determine if social vs nonsocial cues (peer vs light/tone) can serve as discriminative stimuli to reinstate cocaine seeking. In addition, to assess a potential mechanism, an oxytocin (OT) promoter-linked hM3Dq DREADD
Publikováno v:
PsychopharmacologyReferences.
Alcohol use disorder (AUD) has been shown to be associated with a dysregulated stress system. Reducing the stress hormone corticosterone (CORT), that binds to glucocorticoid receptors, may attenuate the rewarding properties of drugs of abuse. However
Autor:
Tracy L. Nolen, Emily D. Denehy, Lindsey R. Hammerslag, Benjamin Carper, Michael T. Bardo, Mark A. Prendergast
Publikováno v:
Psychopharmacology (Berl)
RATIONALE: Opioid use disorder (OUD) is highly comorbid with stress-related disorders, and stress can serve as a trigger for reinstatement of drug seeking. Glucocorticoid receptor (GR) antagonists such as mifepristone (RU-486) may be effective agains
Autor:
Michael T. Bardo, Cassie M. Chandler, Emily D. Denehy, Benjamin A. Carper, Mark A. Prendergast, Tracy L. Nolen
Publikováno v:
Experimental and clinical psychopharmacology.
There is comorbidity between posttraumatic stress disorder (PTSD) and opioid use disorder (OUD), perhaps because PTSD-like stressful experiences early in life alter the hypothalamic-pituitary-adrenal stress axis to increase the risk for OUD. The pres
Publikováno v:
Psychopharmacology. 238:2261-2273
Escalation of drug intake and craving are two DSM-5 hallmark symptoms of opioid use disorder (OUD). This study determined if escalation of intake as modeled by long access (LgA) self-administration (SA) and craving measured by reinstatement are relat