Výsledky vyhledávání - "Michael Szeps"

Interferon α down-regulates telomerase reverse transcriptase and telomerase activity in human malignant and nonmalignant hematopoietic cells

Autor: Dawei Xu, Astrid Gruber, Michael Szeps, Dan Grandér, Sven Erickson, Olle Sangfelt, Stefan Einhorn, Pavel Pisa

Publikováno v: Blood. 96:4313-4318

Recently, the derepressed expression of the catalytic subunit of telomerase, human telomerase reverse transcriptase (hTERT), the enzyme that elongates telomeres, has been implicated as an important step in the immortalization process. The exact regul

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67942f8d8af6e087a17ac0187fd42471
https://doi.org/10.1182/blood.v96.13.4313.h8004313_4313_4318

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Effects of interferon-alpha on cell cycle regulatory proteins in leukemic cells

Autor: Juan Castro, Michael Szeps, Astrid Gruber, Dan Grandér, Stefan Einhorn, Sven Erickson

Publikováno v: Leukemialymphoma. 44(6)

One prominent activity of Interferons (IFNs) is their ability to induce cell cycle arrest, and this effect has furthermore been proposed to be of major importance in mediating the clinical antitumor activity of IFNs. In several IFN sensitive establis

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::195b9b06ad6ec7873b7a50deb6271e44
https://pubmed.ncbi.nlm.nih.gov/12854904

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