Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Michael Superdock"'
Publikováno v:
Case Reports in Oncology, Vol 14, Iss 3, Pp 1621-1626 (2021)
Adult patients with B-cell acute lymphoblastic leukemia (ALL) have higher rates of antecedent and subsequent malignancies. However, synchronous identification of ALL and ovarian cancer is exceedingly rare. We report the unique case of a 65-year-old w
Externí odkaz:
https://doaj.org/article/025c95be9a3e4d4888a3df2be64eeebb
Publikováno v:
Curr Treat Options Oncol
Treatment of older adults with acute myeloid leukemia (AML) is challenging. Therapy decisions must be guided by multiple factors including aging-related conditions (e.g., comorbidities, functional impairment), therapy benefits and risks, patient pref
Autor:
Leonard I. Zon, Roby Joehanes, Eirini Trompouki, Stephen J. Chanock, Alireza Ghamari, Min-Lee Yang, Song Yang, Seraj N. Grimes, Sierra Tseng, Michael Superdock, Daniel E. Bauer, Divya S. Vinjamur, Victoria Chan, Karen Hoi, Richard A. Young, Sonja Boatman, Teresa V. Bowman, Avik Choudhuri, Brian J. Abraham, John L. Rinn, Santhi K. Ganesh, Alan B. Cantor, Kian Hong Kock, Audrey Sporrij, Barbara Hummel, William Mallard, Paul S. Albert, Asher Lichtig, Yi Zhou, Satish K. Nandakumar, Shinichiro Takahashi, Martha L. Bulyk, Leandro M. Colli
Publikováno v:
Nature Genetics
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Nat Genet
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Nat Genet
Genome-wide association studies identify genomic variants associated with human traits and diseases. Most trait-associated variants are located within cell-type-specific enhancers, but the molecular mechanisms governing phenotypic variation are less
Autor:
Yi Zhou, Song Yang, Cristina Santoriello, Karen Adelman, Asher Lichtig, Ryan A. Flynn, Michael Superdock, Meredith E. Stanhope, Brian J. Abraham, Leonard I. Zon, Eugenia Custo Greig, Michael J. Jurynec, Wyatt McCall, Maurizio Fazio, Eliezer Calo, Bilguujin Dorjsuren, Audrey Sporrij, Isaac Adatto, Marian Kalocsay, Telmo Henriques
Publikováno v:
Nature cell biology
The availability of nucleotides has a direct impact on transcription. The inhibition of dihydroorotate dehydrogenase (DHODH) with leflunomide impacts nucleotide pools by reducing pyrimidine levels. Leflunomide abrogates the effective transcription el
Autor:
Jessica Schuster, Paul Stey, Indra Neil Sarkar, James F. Padbury, Alper Uzun, Anthony Agudelo, Michael Superdock
Publikováno v:
Database: The Journal of Biological Databases and Curation
To generate a parsimonious gene set for understanding the mechanisms underlying complex diseases, we reasoned it was necessary to combine the curation of public literature, review of experimental databases and interpolation of pathway-associated gene
Autor:
Ellen M. Durand, Bruce A. Barut, John M. Gansner, David L. Stachura, Alexander D. Leung, Robert I. Handin, Michael Superdock, Megan C. Blair, Leonard I. Zon, Michelle Ammerman, Chafen Lu, Timothy A. Springer
Publikováno v:
Blood. 129(10)
To the editor: An understanding of hematopoietic stem cell (HSC) biology is therapeutically important because of the many human diseases that result from errors in HSC regulation or that can be treated with HSC transplantation. The zebrafish is a pow
Autor:
Song Yang, Michael Superdock, Yi Zhou, Marlies P. Rossmann, Leonard I. Zon, Christopher J. Ott
Publikováno v:
Methods in cell biology. 135
Zebrafish is an excellent genetic and developmental model for the study of vertebrate development and disease. Its ability to produce an abundance of transparent, externally developed embryos has facilitated large-scale genetic and chemical screens f
Autor:
Ninib Baryawno, Jianlong Sun, Leonard I. Zon, Asher Lichtig, Fernando D. Camargo, Nikolaos Barkas, Alejo E. Rodriguez-Fraticelli, Michael Superdock, Tyler Hayes, Audrey Sporrij, Ellen M. Durand, Jimin Guo, Eva M. Fast, Yi Zhou, Margot Manning, Karen Hoi, Leslie Ojeaburu, Song Yang
Publikováno v:
Experimental Hematology. 64:S46