Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Michael Stephen Brieger"'
Autor:
Istvan Kaldor, Ronald George Sherrill, Furfine Eric Steven, David J. Reynolds, John F. Miller, Richard J. Hazen, Michael Stephen Brieger, Andrew Spaltenstein
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 15:3496-3500
A novel series of tyrosine-derived HIV protease inhibitors was synthesized and evaluated for in vitro antiviral activity against wild-type virus and two protease inhibitor-resistant viruses. All of the compounds had wild-type antiviral activities tha
Autor:
David J. Reynolds, Ed W. McLean, Istvan Kaldor, Robert X. Xu, Elizabeth M. Turner, Douglas M. Sammond, C. Webster Andrews, Furfine Eric Steven, Michael R. Hale, Andrew Spaltenstein, Michael Stephen Brieger, Ronald George Sherrill, Mary H. Hanlon, Richard J. Hazen, Roger D. Tung, John F. Miller
Publikováno v:
Bioorganicmedicinal chemistry letters. 16(7)
A novel series of P1 modified HIV protease inhibitors was synthesized and evaluated for in vitro antiviral activity against wild-type virus and protease inhibitor-resistant viruses. Optimization of the P1 moiety resulted in compounds with femtomolar