Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Michael Steidel"'
Autor:
Toby Mathieson, Holger Franken, Jan Kosinski, Nils Kurzawa, Nico Zinn, Gavain Sweetman, Daniel Poeckel, Vikram S. Ratnu, Maike Schramm, Isabelle Becher, Michael Steidel, Kyung-Min Noh, Giovanna Bergamini, Martin Beck, Marcus Bantscheff, Mikhail M. Savitski
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-10 (2018)
The proteome-wide characterization of proteostasis depends on robust approaches to determine protein half-lives. Here, the authors improve the accuracy and precision of mass spectrometry-based quantification, enabling reliable protein half-life deter
Externí odkaz:
https://doaj.org/article/da0726d0c6b44f4fa437f686bacfcd20
Autor:
Peter Wilton, Michael Steidel, Gabriele Krczal, Iris Hermanns, Andreas Pfützner, Alisa Konnerth, Kajohn Boonrod
Publikováno v:
Biology, Vol 6, Iss 2, p 26 (2017)
Adiponectin is one of the most abundant adipokines secreted from adipose tissue. It acts as an endogenous insulin sensitizer and plasma concentrations are inversely correlated with obesity and metabolic syndrome. A decrease in plasma adiponectin leve
Externí odkaz:
https://doaj.org/article/d372bbbeae81409292dfe281abe62006
Autor:
Peter A. Jones, Ashley K. Wiseman, Helai P. Mohammad, Christopher S. Kershaw, Bryan W. King, Ian D. Waddell, Thau F. Ho, Stephen B. Baylin, Morris Muliaditan, Marcus Bantscheff, Elisabeth A. Minthorn, Thilo Werner, Alan P. Graves, Wendy A. Kellner, Phil Chapman, Mehul Patel, Anthony J. Jurewicz, Allan M. Jordan, Emma E. Fairweather, Rab K. Prinjha, Nino Campobasso, Anna Rutkowska, H. Christian Eberl, Ryan G. Kruger, Charles F. McHugh, Michael T. McCabe, Kristin M. Goldberg, Jon Paul Jaworski, Christopher L. Carpenter, Michael Steidel, Stuart Paul Romeril, Dirk A. Heerding, Lourdes Rueda, David T. Fosbenner, Amy N. Taylor, Jacques Briand, Shawn W. Foley, Arthur Groy, Andrew B. Benowitz, Xiaodong Cheng, Donald J. Ogilvie, Paola Grandi, Cunyu Zhang, Mei Li, Sarath Pathuri, Aidan G. Gilmartin, Christian S. Sherk, Juan I. Luengo, Mark Cockerill, Ali Raoof, Alexandra Stowell, Kathryn Keenan, Melissa B. Pappalardi, Makda Mebrahtu, Kristen Wong, Xing Zhang, Jessica L. Handler, Roger J. Butlin, John R. Horton, Susan Merrihew, Charlotte Burt, Dean E. McNulty
Publikováno v:
Nature Cancer. 2:1002-1017
DNA methylation, a key epigenetic driver of transcriptional silencing, is universally dysregulated in cancer. Reversal of DNA methylation by hypomethylating agents, such as the cytidine analogs decitabine or azacytidine, has demonstrated clinical ben
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2228
In order to understand the full mechanism of action of candidate drug molecules, it is critical to thoroughly characterize their interactions with endogenously expressed pharmacological targets and potentially undesired off-targets. Here we describe
Publikováno v:
Methods in Molecular Biology ISBN: 9781071610237
In order to understand the full mechanism of action of candidate drug molecules, it is critical to thoroughly characterize their interactions with endogenously expressed pharmacological targets and potentially undesired off-targets. Here we describe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::40b6647c538d89ed3e2c849da28f33cb
https://doi.org/10.1007/978-1-0716-1024-4_17
https://doi.org/10.1007/978-1-0716-1024-4_17
Autor:
Michael Steidel, Iris Hermanns, Peter Wilton, Kajohn Boonrod, Gabriele Krczal, Andreas Pfützner, Alisa Konnerth
Publikováno v:
Biology
Biology; Volume 6; Issue 2; Pages: 26
Biology, Vol 6, Iss 2, p 26 (2017)
Biology; Volume 6; Issue 2; Pages: 26
Biology, Vol 6, Iss 2, p 26 (2017)
Adiponectin is one of the most abundant adipokines secreted from adipose tissue. It acts as an endogenous insulin sensitizer and plasma concentrations are inversely correlated with obesity and metabolic syndrome. A decrease in plasma adiponectin leve
Autor:
Isabelle Becher, Daniel Poeckel, Maike Schramm, Kyung-Min Noh, Michael Steidel, Mikhail M. Savitski, Vikram S. Ratnu, Gavain Sweetman, Giovanna Bergamini, Holger Franken, Nils Kurzawa, Martin Beck, Marcus Bantscheff, Nico Zinn, Toby Mathieson, Jan Kosinski
Publikováno v:
Nature Communications
Nature Communications, Vol 9, Iss 1, Pp 1-10 (2018)
Nature Communications, Vol 9, Iss 1, Pp 1-10 (2018)
A better understanding of proteostasis in health and disease requires robust methods to determine protein half-lives. Here we improve the precision and accuracy of peptide ion intensity-based quantification, enabling more accurate protein turnover de