Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Michael Staup"'
Autor:
Daniel G. Rudmann, Danielle L. Brown, Robert Klopfleisch, Thomas Westerling-Bui, Aleksandra Zuraw, Michael Staup, Famke Aeffner
Publikováno v:
Toxicologic Pathology. 49:773-783
Digital tissue image analysis is a computational method for analyzing whole-slide images and extracting large, complex, and quantitative data sets. However, as with any analysis method, the quality of generated results is dependent on a well-designed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8785dd00fb0a0672afbfb12eb1b8556
https://doi.org/10.1177/0192623320980310
https://doi.org/10.1177/0192623320980310
Publikováno v:
Toxicologic Pathology. 48:37-48
Qualitative histopathology has been the gold standard for evaluation of morphological tissue changes in all organ systems, including the peripheral nervous system. However, the human eye is not sensitive enough to detect small changes in quantity or
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40fb7d29361b0d3ab4f92d04a3b8e0b1
https://doi.org/10.1177/0192623319854746
https://doi.org/10.1177/0192623319854746
Autor:
Julie F. Foley, Min Shi, Jingli Liu, Lindsay A Santiago, Lysandra Castro, Michael Staup, Linda Yu, Trey Saddler, Linda S. Birnbaum, William Xue, Alanna Burwell, Darlene Dixon, Norris D Flagler
Publikováno v:
Toxicol Res Appl
Toxicology Research and Application, Vol 5 (2021)
Toxicology Research and Application, Vol 5 (2021)
Tetrabromobisphenol A (TBBPA) is a brominated flame retardant that induces endometrial adenocarcinoma and other uterine tumors in Wistar Han rats; however, early molecular events or biomarkers of TBBPA exposure remain unknown. We investigated the eff
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d289bf433bda9dad3e101b0e75bcded
https://europepmc.org/articles/PMC8774279/
https://europepmc.org/articles/PMC8774279/
Autor:
Suramya Waidyanatha, Keith R. Shockley, Robert C. Sills, Jesse D. Cushman, Mark F. Cesta, Sheba R Churchill, Michael Staup, Peter B. Little, Danielle L. Brown, Veronica G. Robinson, Mamta Behl, Crystal L. Johnson, David M Kurtz, G. Allan Johnson, Robert J. Anderson, Danica M.K. Andrews
Publikováno v:
Toxicol Pathol
It is well established that hexachlorophene, which is used as an antibacterial agent, causes intramyelinic edema in humans and animal models. The hexachlorophene myelinopathy model, in which male Sprague-Dawley rats received 25 to 30 mg/kg hexachloro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef4bcaf64132171fad9ca26d7aea5a7e
https://pubmed.ncbi.nlm.nih.gov/33334257
https://pubmed.ncbi.nlm.nih.gov/33334257
Autor:
Victoria Plamadeala Johnson, Emanuel Zycband, Stacey Conarello, Yonghua Zhu, David E. Kelley, Michael Staup, Jin Shang, Mark D. Erion, Dan Xie, Keefe Chng, Gladys Arreaza, Stephen F. Previs, Liangsu Wang, Margaret van Heek, Diane Levitan, Yixin Wang, Karni Schlessinger, Sandra C. Souza, Ying Chen, Franklin Liu
Publikováno v:
American Journal of Physiology-Endocrinology and Metabolism. 312:E235-E243
Insulin resistance and diabetes can develop spontaneously with obesity and aging in rhesus monkeys, highly similar to the natural history of obesity, insulin resistance, and progression to type 2 diabetes in humans. The current studies in obese rhesu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ea6be096903d99992ef951ec8277fde
https://doi.org/10.1152/ajpendo.00398.2016
https://doi.org/10.1152/ajpendo.00398.2016
Publikováno v:
Journal of Visualized Experiments.
The intravenous glucose tolerance test (IVGTT) plays a key role in the characterization of glucose homeostasis. When taken together with serum biochemical profiles, inclusive of blood glucose levels in both the fed and fasted state, HbA1c, insulin le
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4355d3d31216132881097ed474a77ede
https://doi.org/10.3791/52895
https://doi.org/10.3791/52895
Autor:
Haihua Gu, Yixin Jim Wang, Yongqiang Liu, Xiaoli Wang, Francine M. Gregoire, Guofeng Sun, Michael Staup, Keefe Chng, Bingdi Wang, Shuang Mei, Yong-Fu Xiao
Publikováno v:
BMC Cardiovascular Disorders
Background Diabetes is one of the major risk factors for cardiomyopathy and heart failure with reduced ejection fraction (EF) and highly associated with left ventricular (LV) dysfunction in human. This study aimed 1) to noninvasively assess cardiac f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c83316a9c5b368207f4599f7de38507
http://europepmc.org/articles/PMC4628306
http://europepmc.org/articles/PMC4628306
Autor:
Francine M. Gregoire, Michael Staup, Sheng Guo, Wubin Qian, Michael Benzinou, Fenglai Du, Xiaoli Wang, Xuan Chen, Yaxiong Chen, Keefe Chng, Bingdi Wang, Yixin Wang, Yong-Fu Xiao, Yupeng Fang
Publikováno v:
Journal of Diabetes & Metabolism.
Although Type 2 Diabetes Mellitus (T2DM) is well characterized Non-Human Primate (NHP), the phenotypes of diabetic nephropathy, and its molecular mechanisms are not well studied in NHPs. Diabetic nephropathy in cynomolgus macaques with spontaneous dy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c74b04b773014945fde3de1759ed7b77
https://doi.org/10.4172/2155-6156.1000334
https://doi.org/10.4172/2155-6156.1000334
Autor:
Donald J. Stehouwer, Michael Staup
Publikováno v:
Brain research. 1068(1)
Neonatal rats suspended in harnesses, limbs hanging freely, and injected with 100 mg/kg l-3,4-dihydroxyphenylalanine (L-DOPA), engage in a behavior (air stepping) that closely resembles spontaneous locomotion. Rats no longer demonstrate this response
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40ed9d5281d2d9a9e1613f8f15ec15ff
https://pubmed.ncbi.nlm.nih.gov/16386717
https://pubmed.ncbi.nlm.nih.gov/16386717
Publikováno v:
Toxicologic Pathology; Jun2021, Vol. 49 Issue 4, p714-719, 6p