Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Michael Snaith"'
Autor:
Juan Carlos Yam-Puc, Lingling Zhang, Raul A Maqueda-Alfaro, Laura Garcia-Ibanez, Yang Zhang, Jessica Davies, Yotis A Senis, Michael Snaith, Kai-Michael Toellner
Publikováno v:
iScience, Vol 24, Iss 2, Pp 102038- (2021)
Summary: It is still not clear how B cell receptor (BCR) signaling intensity affects plasma cell (PC) and germinal center (GC) B cell differentiation. We generated Cγ1Cre/wtPtpn6fl/fl mice where SHP-1, a negative regulator of BCR signaling, is delet
Externí odkaz:
https://doaj.org/article/2683f28e2d1c4ba08fa4c42ead60d9c9
Autor:
Thomas Lundåsen, Eva-Marie Andersson, Michael Snaith, Helena Lindmark, Johanna Lundberg, Ann-Margret Östlund-Lindqvist, Bo Angelin, Mats Rudling
Publikováno v:
PLoS ONE, Vol 7, Iss 5, p e37787 (2012)
Interruption of the enterohepatic circulation of bile acids increases cholesterol catabolism, thereby stimulating hepatic cholesterol synthesis from acetate. We hypothesized that such treatment should lower the hepatic acetate pool which may alter tr
Externí odkaz:
https://doaj.org/article/363f15d1450d4741babf3feaa4a1efe4
Autor:
Christopher J Lelliott, Gema Medina-Gomez, Natasa Petrovic, Adrienn Kis, Helena M Feldmann, Mikael Bjursell, Nadeene Parker, Keira Curtis, Mark Campbell, Ping Hu, Dongfang Zhang, Sheldon E Litwin, Vlad G Zaha, Kimberly T Fountain, Sihem Boudina, Mercedes Jimenez-Linan, Margaret Blount, Miguel Lopez, Aline Meirhaeghe, Mohammad Bohlooly-Y, Leonard Storlien, Maria Strömstedt, Michael Snaith, Matej Oresic, E Dale Abel, Barbara Cannon, Antonio Vidal-Puig
Publikováno v:
PLoS Biology, Vol 4, Iss 11, p e369 (2006)
The transcriptional coactivator peroxisome proliferator-activated receptor-gamma coactivator-1beta (PGC-1beta) has been implicated in important metabolic processes. A mouse lacking PGC-1beta (PGC1betaKO) was generated and phenotyped using physiologic
Externí odkaz:
https://doaj.org/article/a339d534b4bb4152b54fabbda95e6768
Autor:
Michael Snaith, Yang Zhang, Juan Carlos Yam-Puc, Raúl Antonio Maqueda-Alfaro, Jessica Davies, Laura Garcia-Ibanez, Lingling Zhang, Yotis A. Senis, Kai-Michael Toellner
Publikováno v:
iScience
iScience, Vol 24, Iss 2, Pp 102038-(2021)
iScience, Vol 24, Iss 2, Pp 102038-(2021)
Summary It is still not clear how B cell receptor (BCR) signaling intensity affects plasma cell (PC) and germinal center (GC) B cell differentiation. We generated Cγ1Cre/wtPtpn6fl/fl mice where SHP-1, a negative regulator of BCR signaling, is delete
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::635565f37c548423c72f49e295d8169d
http://europepmc.org/articles/PMC7822941
http://europepmc.org/articles/PMC7822941
Autor:
Michael Snaith, Raúl Antonio Maqueda-Alfaro, Juan Carlos Yam-Puc, Yang Zhang, Laura Garcia-Ibanez, K.M. Toellner, Lingling Zhang, Yotis A. Senis, J Davies
It is still not clear how B-cell receptor (BCR) signalling intensity affects plasma cell and germinal centre (GC) B cell differentiation. We generated Cγ1Cre/+Ptpn6fl/fl mice where SHP-1, a negative regulator of BCR signalling, is deleted rapidly af
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2f684527c4bc129b8dce2743b6deea9e
https://doi.org/10.1101/2020.07.29.226662
https://doi.org/10.1101/2020.07.29.226662
Splitmix assembly of DNA libraries for ultrahigh throughput on-bead screening of functional proteins
Autor:
Michael Herger, Michael Snaith, Laurens Lindenburg, Florian Hollfelder, Kayleigh van de Wiel, Tuomas Huovinen
Publikováno v:
Nucleic Acids Research
Site-saturation libraries reduce protein screening effort in directed evolution campaigns by focusing on a limited number of rationally chosen residues. However, uneven library synthesis efficiency leads to amino acid bias, remedied at high cost by e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ac37768959493ead79a38512ea07a32
https://pubmed.ncbi.nlm.nih.gov/32383757
https://pubmed.ncbi.nlm.nih.gov/32383757
Autor:
William H. Colledge, Maria Schacker, Yi-Han Cheng, Mélanie A. Eckersley-Maslin, Richard Michael Snaith
Publikováno v:
Stem Cell Research
Stem Cell Research, Vol 48, Iss, Pp 101931-(2020)
Stem Cell Research, Vol 48, Iss, Pp 101931-(2020)
Graphical abstract
Highlights • Reduced expression of Gtl2, Rian and Mirg in ES cells compromised survival of chimaeric fetuses. • Reduced expression of Gtl2, Rian and Mirg was associated with hypermethylation. • Compromised ES cells can b
Highlights • Reduced expression of Gtl2, Rian and Mirg in ES cells compromised survival of chimaeric fetuses. • Reduced expression of Gtl2, Rian and Mirg was associated with hypermethylation. • Compromised ES cells can b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c83e81a5893d6ebcc78c480212a65bc5
https://doi.org/10.1016/j.scr.2020.101931
https://doi.org/10.1016/j.scr.2020.101931
Autor:
Marianne Wedin, Anders Elmgren, Andrea Ahnmark, Mohammad Bohlooly-Y, Nigel Turner, Misak Yazdi, Michael Snaith, Anna-Karin Asztély, Daniel Lindén, Fredrik Osla, Lena William-Olsson, Sandra A. Schreyer
Publikováno v:
Biochemical and Biophysical Research Communications. 369:1065-1070
Glycerol-3-phosphate acyltransferase (GPAT) is involved in triacylglycerol (TAG) and phospholipid synthesis, catalyzing the first committed step. In order to further investigate the in vivo importance of the dominating mitochondrial variant, GPAT1, a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::165962e45eb3c83164d3b972d196e5a1
https://doi.org/10.1016/j.bbrc.2008.02.156
https://doi.org/10.1016/j.bbrc.2008.02.156
Autor:
Jan Oscarsson, Michael Snaith, David Svensson, Karolina Ploj, Lennart Svensson, Jan Törnell, Mikael Bjursell, Mohammad Bohlooly-Y, Anna-Karin Gerdin
Publikováno v:
Diabetes. 55:725-733
The hypothalamic peptide melanin-concentrating hormone (MCH) plays important roles in energy homeostasis. Animals overexpressing MCH develop hyperphagia, obesity, and insulin resistance. In this study, mice lacking both the MCH receptor-1 (MCHr1 knoc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65caff4d0fe6d2e90c5d6d56652f277b
https://doi.org/10.2337/diabetes.55.03.06.db05-1302
https://doi.org/10.2337/diabetes.55.03.06.db05-1302
Publikováno v:
Medical Education. 38:1253-1260
Background Professional bodies have expressed concerns that medical students lack appropriate knowledge in musculoskeletal medicine despite its high prevalence of use within the community. Changes in curriculum and teaching strategies may be contribu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1d2017ad61ad81ba8e1aaa8f3dbbc62
https://doi.org/10.1111/j.1365-2929.2004.02017.x
https://doi.org/10.1111/j.1365-2929.2004.02017.x