Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Michael Simonich"'
Publikováno v:
Toxicological Sciences.
The existence of thousands of per- and polyfluoroalkyl substances (PFAS) and evidence that some cause adverse health effects has created immense need to better understand PFAS toxicity and to move beyond one-chemical-at-a-time approaches to hazard as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1885789a7647cd1298b84766e91de207
https://doi.org/10.1093/toxsci/kfad051
https://doi.org/10.1093/toxsci/kfad051
Autor:
Sean M. Bugel, Crystal Y. Usenko, Lisa Truong, Robert L. Tanguay, Michael Simonich, Anna C. Chlebowski, Staci L. Massey Simonich
Publikováno v:
Reproductive Toxicology. 65:139-147
The use of zebrafish for high throughput screening (HTS) for chemical bioactivity assessments is becoming routine in the fields of drug discovery and toxicology. Here we report current recommendations from our experiences in zebrafish HTS. We compare
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a6b13a44264db08402ece0b1d580922
https://doi.org/10.1016/j.reprotox.2016.05.015
https://doi.org/10.1016/j.reprotox.2016.05.015
Autor:
Jiangfei Chen, Kuangfei Lin, Changjiang Huang, Yuxin Zhao, Chenglian Bai, Michael Simonich, Lelin Li, Qiaoxiang Dong, Robert L. Tanguay, Shangfei Nie
Publikováno v:
Neurotoxicology and Teratology. 56:9-15
The toxicity of tetrabromobisphenol A (TBBPA) has been extensively studied because of its high production volume. TBBPA is toxic to aquatic fish based on acute high concentration exposure tests, and few studies have assessed the behavioral effects of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4caf57510e180e18bf7acc1b0a85a2e0
https://doi.org/10.1016/j.ntt.2016.05.008
https://doi.org/10.1016/j.ntt.2016.05.008
Autor:
Leif Abrell, Reyes Sierra-Alvarez, Christopher I. Olivares, Jon Chorover, Michael Simonich, Jim A. Field, Robert L. Tanguay
Publikováno v:
Environmental Toxicology and Chemistry. 35:2774-2781
2,4-Dinitroanisole (DNAN) is an emerging insensitive munitions compound that readily undergoes anaerobic nitro-group reduction to 2-methoxy-5-nitroaniline (MENA) and 2,4-diaminoanisole (DAAN), followed by formation of unique azo dimers. Currently the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6859ec8bf2be8ff3a0e8bbc958e8ac8d
https://doi.org/10.1002/etc.3446
https://doi.org/10.1002/etc.3446
Autor:
Jörg E. Drewes, Thomas Letzel, Stefan Bieber, Tanja Rauch-Williams, Michael Hannemann, Bozo Zonja, Damià Barceló, Sandra Pérez, Jennifer E. Schollée, Emma L. Schymanski, Juliane Hollender, Bettina Seiwert, Cindy Weidauer, Kristin Hirte, Thorsten Reemtsma, Sylvia Grosse, Wolfgang Schulz, Thomas Lucke, Angela Kolb, Manfred Sengl, Marion Letzel, Steffen Ruppe, Akash M. Sadaria, Samuel D. Supowit, Rolf U. Halden, Christopher I. Olivares, Leif Abrell, Jon Chorover, Michael Simonich, Robert L. Tanguay, Reyes Sierra-Alvarez, Jim A. Field, He Zhao, Penghui Du, Di Zhang, Hongbin Cao, Laura Mast, Julia Regnery, Dong Li, Simon Roberts, Christopher Higgins, Jonathan O. Sharp
Autor:
Kim A. Anderson, Andrea L. Knecht, Melissa M. Matzke, Annika J. Swanson, Katrina M. Waters, Michael Simonich, Lisa Truong, Britton C. Goodale, Robert L. Tanguay
Publikováno v:
Toxicology and Applied Pharmacology. 271:266-275
Oxygenated polycyclic aromatic hydrocarbons (OPAHs) are byproducts of combustion and photo-oxidation of parent PAHs. OPAHs are widely present in the environment and pose an unknown hazard to human health. The developing zebrafish was used to evaluate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b58e518c95657305bcdaacfae55da02
https://doi.org/10.1016/j.taap.2013.05.006
https://doi.org/10.1016/j.taap.2013.05.006
Autor:
Xiaotong Wang, Lingnan Zhang, Changjiang Huang, Dingding Wang, Ting Wang, Qiaoxiang Dong, Jiangfei Chen, Xiaoqing Ge, Michael Simonich, Robert L. Tanguay
Publikováno v:
Environmental pollution (Barking, Essex : 1987). 218
Perfluorooctanesulphonic acid (PFOS) is a ubiquitous contaminant in the aquatic environment and our earlier studies demonstrated that chronic PFOS exposures lead to a female-biased sex ratio and decreased sperm quality in male zebrafish. The underlyi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4acd759d64032c55056a9f498bd23f69
https://pubmed.ncbi.nlm.nih.gov/27496563
https://pubmed.ncbi.nlm.nih.gov/27496563
Publikováno v:
Methods in Molecular Biology ISBN: 9781493963447
The field of toxicology is undergoing a vast change with high-throughput (HT) approaches that rapidly query huge swaths of chemico-structural space for bioactivity and hazard potential. Its practicality is due in large part to switching from high-cos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5f11e39310cbf5c22610ab708f1d4442
https://doi.org/10.1007/978-1-4939-6346-1_10
https://doi.org/10.1007/978-1-4939-6346-1_10
Autor:
Robert L. Tanguay, Michael Simonich, Jiangfei Chen, Qiaoxiang Dong, Chenglian Bai, Lidan Zheng, Changjiang Huang
Publikováno v:
Neurotoxicology and Teratology. 33:721-726
Trimethyltin chloride (TMT) is a neurotoxicant that is widely present in the aquatic environment, primarily from the manufacture of PVC plastic, but few studies have evaluated aquatic neurotoxicity. We have examined TMT dose-dependent malformation an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79691dbdd8df53a0d6b8d20e523624b2
https://doi.org/10.1016/j.ntt.2011.09.003
https://doi.org/10.1016/j.ntt.2011.09.003
Autor:
Anthony M. DeLuca, Jacob A. Freeman, Michael Simonich, Michael V. Ol, Ian Bautista, Mark F. Reeder
Publikováno v:
24th AIAA Aerodynamic Measurement Technology and Ground Testing Conference.
The Air Force Research Lab, Munitions Directorate has designed a man-portable Micro-Air-Vehicle (MAV) used for on-the-spot reconnaissance and post-strike Battle Damage Assessment. The wing on this 24′′ span, 6′′ chord MAV consists of a flexib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0663b9bc3ac55c38684dc30f3df519f5
https://doi.org/10.2514/6.2004-2396
https://doi.org/10.2514/6.2004-2396