Zobrazeno 1 - 10
of 70
pro vyhledávání: '"Michael Serby"'
Metabolism and Disposition of Pan-Genotypic Inhibitor of Hepatitis C Virus NS5A Ombitasvir in Humans
Autor:
Volker Fischer, Olga Kavetskaia, Jens Sydor, Bruce W. Surber, Anthony J. Lee, Sonia M. de Morais, Rajeev M. Menon, Junli Ma, Jianwei Shen, Michael Serby, Prajakta S. Badri
Publikováno v:
Drug Metabolism and Disposition. 44:1148-1157
Ombitasvir (also known as ABT-267) is a potent inhibitor of hepatitis C virus (HCV) nonstructural protein 5A (NS5A), which has been developed in combination with paritaprevir/ritonavir and dasabuvir in a three direct-acting antiviral oral regimens fo
Autor:
Kennan C. Marsh, Volker Fischer, Jianwei Shen, Anthony J. Lee, Olga Kavetskaia, Aimee Reed, Xiaomei Zhang, Rajeev M. Menon, Michael Serby, Amit Khatri
Publikováno v:
Drug Metabolism and Disposition. 44:1164-1173
Paritaprevir (also known as ABT-450), a potent NS3-4A serine protease inhibitor [identified by AbbVie (North Chicago, IL) and Enanta Pharmaceuticals (Watertown, MA)] of the hepatitis C virus (HCV), has been developed in combination with ombitasvir an
Publikováno v:
Comprehensive Psychiatry, Vol 55, Iss 4, Pp 849-855 (2014)
Background: Psychopharmacology and psychotherapy are the two main therapies in mental health. It is common practice to consider adverse events (AEs) of medications, but it’s not clear this occurs with psychotherapy. Aim: This study investigates the
Autor:
Srirajan Vaidyanathan, Hong Liu, Martin Dunbar, Anthony J. Lee, Ahmed Salem, Katty Wan, Sonia Maria de Morais, Shekman Wong, Melissa J. Michmerhuizen, Jens Sydor, Michael Serby, James Sawicki, Suresh Agarwal, Yanbin Lao
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 45(3)
Venetoclax (ABT-199), a B-cell lymphoma-2 (Bcl-2) protein inhibitor, is currently in clinical development for the treatment of hematologic malignancies. We characterized the absorption, metabolism, and excretion of venetoclax in humans. After a singl
Publikováno v:
The International Journal of Psychiatry in Medicine. 40:93-96
A 90-year-old woman who had received more than 100 electroconvulsive treatments (ECT) over many years requested another course for depression. After the third ECT, an electrocardiogram showed new T-wave inversion (V2–V6) and ST elevation (V2). Cath
Autor:
Volker Fischer, Anthony J. Lee, Michael Serby, Olga Kavetskaia, Aimee Reed, Xiaomei Zhang, Xia Wan, Rajeev M. Menon, Kennan C. Marsh, Jianwei Shen
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 44(8)
Dasabuvir [also known as ABT-333 or N-(6-(3-(tert-butyl)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-2-methoxyphenyl)naphthalen-2-yl)methanesulfonamide] is a potent non-nucleoside NS protein 5B polymerase inhibitor of the hepatitis C virus (HCV) and
Publikováno v:
Journal of Psychotherapy Integration. 15:213-223
Autor:
Deborah B. Marin, Dushyant P. Purohit, Vahram Haroutunian, Michael Serby, Adam M. Brickman, Melinda Lantz, Richard C. Mohs, Kenneth L. Davis
Publikováno v:
The American Journal of Geriatric Psychiatry. 11:371-374
Objectives Authors compared the degrees of cognitive deficit among individuals with Alzheimer disease (AD), the Lewy-body variant of AD (LBV), and "pure" dementia with Lewy bodies (DLB); and compared cortical Lewy body (LB) counts in LBV versus DLB a
Autor:
Philip D. Harvey, Marianne Goodman, Harold W. Koenigsberg, Larry J. Siever, Vivian Mitropoulou, Antonia S. New, Frances Schopick, Jeremy M. Silverman, Michael Serby, James Schmeidler
Publikováno v:
American Journal of Psychiatry. 159:784-788
This study sought to understand affective instability among patients with borderline personality disorder by examining the degree of instability in six affective domains. The authors also examined the subjective intensity with which moods are experie
Autor:
Antonia S. New, Vivian Mitropoulou, Michael Serby, Philip D. Harvey, Larry J. Siever, Jeremy M. Silverman, Frances Schopick, Harold W. Koenigsberg, Marianne Goodman
Publikováno v:
Journal of Personality Disorders. 15:358-370
This study examines the degree to which two putative biologically influenced personality traits, affective instability and impulsive aggression, are associated with some of the interpersonal and intrapsychic disturbances of borderline personality dis