TB and HIV induced immunosenescence: where do vaccines play a role?

Autor: Mona Singh, Bhumika Patel, Michael Seo, Phillip Ahn, Nejma Wais, Haley Shen, SriHarsha Nakka, Priya Kishore, Vishwanath Venketaraman

Publikováno v: Frontiers in Aging, Vol 5 (2024)

This paper tackles the complex interplay between Human Immunodeficiency virus (HIV-1) and Mycobacterium tuberculosis (M. tuberculosis) infections, particularly their contribution to immunosenescence, the age-related decline in immune function. Using

Externí odkaz: https://doaj.org/article/8a4f7774c42c47e8adc74d10174de5c5

Developing prediction models when there are systematically missing predictors in individual patient data meta‐analysis

Autor: Orestis Efthimiou, Toshi Furukawa, Michael Seo, Eirini Karyotaki

Publikováno v: Research Synthesis Methods, 14(3), 455-467. Wiley
Seo, M, Furukawa, T A, Karyotaki, E & Efthimiou, O 2023, ' Developing prediction models when there are systematically missing predictors in individual patient data meta-analysis ', Research Synthesis Methods, vol. 14, no. 3, pp. 455-467 . https://doi.org/10.1002/jrsm.1625

Clinical prediction models are widely used in modern clinical practice. Such models are often developed using individual patient data (IPD) from a single study, but often there are IPD available from multiple studies. This allows using meta-analytica

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f939897eeabd9b01c201dab0e4e93aa
https://doi.org/10.1002/jrsm.1625

Personalized Prediction of Alzheimer's Disease and Its Treatment Effects by Donepezil: An Individual Participant Data Meta-Analysis of Eight Randomized Controlled Trials

Autor: Kazufumi Yoshida, Michael Seo, Yan Luo, Ethan Sahker, Andrea Cipriani, Stefan Leucht, Takeshi Iwatsubo, Orestis Efthimiou, Toshiaki A. Furukawa

Publikováno v: Yoshida, Kazufumi; Seo, Michael; Luo, Yan; Sahker, Ethan; Cipriani, Andrea; Leucht, Stefan; Iwatsubo, Takeshi; Efthimiou, Orestis; Furukawa, Toshiaki A (2022). Personalized Prediction of Alzheimer's Disease and Its Treatment Effects by Donepezil: An Individual Participant Data Meta-Analysis of Eight Randomized Controlled Trials. Journal of Alzheimer's disease, 89(4), pp. 1143-1157. IOS Press 10.3233/JAD-220263

BACKGROUND Patient characteristics may predict the progression of Alzheimer's disease (AD) and may moderate the effects of donepezil. OBJECTIVE To build a personalized prediction model for patients with AD and to estimate patient-specific treatment e

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff5ee6ee2b9454ea8807270760e2b29b
https://pubmed.ncbi.nlm.nih.gov/35988219

The Kilim plot: A tool for visualizing network meta‐analysis results for multiple outcomes

Autor: Areti Angeliki Veroniki, Andrea Cipriani, Orestis Efthimiou, Toby Pillinger, Michael Seo, Anneka Tomlinson, Georgia Salanti, Toshi A. Furukawa

Publikováno v: Research Synthesis Methods
Seo, Michael; Furukawa, Toshi A; Veroniki, Areti Angeliki; Pillinger, Toby; Tomlinson, Anneka; Salanti, Georgia; Cipriani, Andrea; Efthimiou, Orestis (2021). The Kilim plot: A tool for visualizing network meta-analysis results for multiple outcomes. Research Synthesis Methods, 12(1), pp. 86-95. Wiley 10.1002/jrsm.1428

Network meta-analysis (NMA) can be used to compare multiple competing treatments for the same disease. In practice, usually a range of outcomes is of interest. As the number of outcomes increases, summarizing results from multiple NMAs becomes a nont

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83af5879678b6b0932bf7432266ac393

Comparison of revascularization strategies in patients with acute coronary syndrome and multivessel coronary disease: A systematic review and network meta-analysis

Autor: Christopher H. Schmid, Mohammad Saud Khan, Sohail Ikram, Michael Seo, Abdelmoniem Moustafa, Abdullah Irfan Khan, Abdur Rahman Khan, Farah Yasmin, Muhammad Usman, Ankur Kalra

BACKGROUND Whether revascularization should be performed as multivessel intervention at the time of index procedure (MV-index), staged procedure (MV-staged), or culprit only intervention (COI) in patients with multivessel disease (MVD) presenting wit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b25b7311024a611fb379f0cb562b3ee5