Zobrazeno 1 - 10
of 498
pro vyhledávání: '"Michael Sela"'
Autor:
Michael Sela
Publikováno v:
Biotechnologia Acta, Vol 6, Iss 4, Pp 16-19 (2013)
History of developing synergy between monoclonal antibodies, anti-tumor activity of monoclonal antibodies against tyrosine-kinases receptors EGFR/ErbB-1 and HER2/ErbB-2 as well as growth factor VEGF in various combinations are considered in the artic
Externí odkaz:
https://doaj.org/article/131a1d1b5fb0490199e9860453a9c3e0
Publikováno v:
Glia. 66:1098-1117
To elucidate mechanisms contributing to cortical pathology in multiple sclerosis (MS), we investigated neurovascular aberrations, in particular the association of astrocytes with cortical neurons and blood vessels, in mice induced with experimental a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ecfde1d78d4e3fc4acec21f650eb352
https://doi.org/10.1002/glia.23304
https://doi.org/10.1002/glia.23304
Autor:
Ruth Arnon, Elias Shezen, Rina Aharoni, Dekel D. Bar-Lev, Michael Sela, Chava Rosen, Yair Reisner, Ofra Golani
Publikováno v:
Journal of Neuroimmunology. 301:7-11
The lack of biomarkers is a major obstacle for investigating myelin repair. We used metabolic incorporation of the choline analog - propargyl-choline (P-Cho) to label and visualize newly synthesized myelin in the CNS of mice induced with experimental
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72c5539ff0e5a6a72f59d822beebe0cf
https://doi.org/10.1016/j.jneuroim.2016.10.015
https://doi.org/10.1016/j.jneuroim.2016.10.015
Autor:
Nishanth Belugali Nataraj, Donatella Romaniello, Bilha Schechter, Soma Ghosh, Michael Sela, Ruth Maron, Silvia Carvalho, Ashish Noronha, Ilaria Marrocco, Yosef Yarden
Publikováno v:
Biochemical and biophysical research communications. 513(1)
By year 2025 pancreatic ductal adenocarcinoma (PDAC) is expected to become the second leading cause of cancer related death. However, other than improved chemotherapy and a small molecule inhibitor of the epidermal growth factor receptor (EGFR), no t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0720f4ee8a0d65f8ba85afd165eff098
https://pubmed.ncbi.nlm.nih.gov/30952434
https://pubmed.ncbi.nlm.nih.gov/30952434
Autor:
Dekel D. Bar-Lev, Michael Sela, Nofar Schottlender, Michael Tsoory, Ruth Arnon, Rina Aharoni, Raya Eilam
Publikováno v:
Scientific Reports
Scientific Reports, Vol 9, Iss 1, Pp 1-15 (2019)
Scientific Reports, Vol 9, Iss 1, Pp 1-15 (2019)
The severe motor impairment in the MS animal model experimental autoimmune encephalomyelitis (EAE) obstructs the assessment of cognitive functions. We developed an experimental system that evaluates memory faculties in EAE-affected mice, irrespective
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9983bc04e985131f04b8d97d2d4a502
http://europepmc.org/articles/PMC6412002
http://europepmc.org/articles/PMC6412002
Publikováno v:
British Journal of Pharmacology. 173:1407-1424
Antibody-based therapy of cancer employs monoclonal antibodies (mAbs) specific to soluble ligands, membrane antigens of T-lymphocytes or proteins located at the surface of cancer cells. The latter mAbs are often combined with cytotoxic regimens, beca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0eeb463442ddc2b62d9d8fea99c9305b
https://doi.org/10.1111/bph.13450
https://doi.org/10.1111/bph.13450
Publikováno v:
Biographical Memoirs of Fellows of the Royal Society. 62:267-275
Ephraim Katchalski-Katzir was a leading researcher in the development of polyamino acids, which allowed new insights into the reactions and behaviour of proteins. His work developed pathways into the exploration and investigation of antigenicity. He
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5aeacb21db01ef9511ac5f0bdf1c44c3
https://doi.org/10.1098/rsbm.2016.0015
https://doi.org/10.1098/rsbm.2016.0015
Autor:
Michael Sela, Sandra Leistner-Segal, Ruth Arnon, Dana Hirsch, Rina Aharoni, Lihi Radomir, Tali Feferman, Nofar Schottlender, Raya Eilam
Publikováno v:
Journal of Neuroimmunology. 345:577281
To identify the mechanisms relevant for the therapeutic effect of glatiramer acetate (GA), we studied T- and B- regulatory cells as well as GM-CSF expression in mice recovered from experimental autoimmune encephalomyelitis (EAE). Selective depletion
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::141a622ac3ed0c0034aa490957522de4
https://doi.org/10.1016/j.jneuroim.2020.577281
https://doi.org/10.1016/j.jneuroim.2020.577281
Autor:
Michael Sela
Publikováno v:
Biochemical and Biophysical Research Communications. 464:379-385
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c408c767ead24b0dbf7d8244112e46ae
https://doi.org/10.1016/j.bbrc.2015.06.030
https://doi.org/10.1016/j.bbrc.2015.06.030
Autor:
Dekel D. Bar-Lev, Ruth Arnon, Rina Aharoni, Michael Sela, Patrizia LoPresti, Michael Tsoory, Smadar Levin-Zaidman, Renana From, Raya Eilam
Publikováno v:
Glia. 62:649-665
Myelinogenesis in the mammal nervous system occurs predominantly postnatally. Glatiramer acetate (GA), a drug for the treatment for multiple sclerosis (MS), has been shown to induce immunomodulation and neuroprotection in the inflamed CNS in MS and i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::57358eafc3f9078e55aaf7bf38acc9fa
https://doi.org/10.1002/glia.22632
https://doi.org/10.1002/glia.22632