Chronic tracheostomy care of ventilator‐dependent and ‐independent children: Clinical practice patterns of pediatric respirologists in a publicly funded (Canadian) healthcare system

Autor: Aaron St‐Laurent, David Zielinski, Adam Qazi, Aceel AlAwadi, Athari Almajed, Darryl J. Adamko, Tareq Alabdoulsalam, Jackie Chiang, Michael Derynck, Chris Gerdung, Karen Kam, Sherri L. Katz, Ian MacLusky, Kevan Mehta, Dimas Mateos, The Thanh D. Nguyen, Jean‐Paul Praud, Frederic Proulx, Michael Seear, Mary Jane Smith, David Wensley, Reshma Amin

Publikováno v: Pediatric Pulmonology. 58:140-151

To describe the current clinical practice patterns of Canadian pediatric respirologists at pediatric tertiary care institutions regarding chronic tracheostomy tube care and management of home invasive ventilation.A pediatric respirologist/pediatricia

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7326c6ac0008144cbdd54ec6f51d0759
https://doi.org/10.1002/ppul.26171

Human germline heterozygous gain-of-function STAT6 variants cause severe allergic disease

Autor: Mehul Sharma, Daniel Leung, Mana Momenilandi, Lauren C.W. Jones, Lucia Pacillo, Alyssa E. James, Jill R. Murrell, Selket Delafontaine, Jesmeen Maimaris, Maryam Vaseghi-Shanjani, Kate L. Del Bel, Henry Y. Lu, Gilbert T. Chua, Silvia Di Cesare, Oriol Fornes, Zhongyi Liu, Gigliola Di Matteo, Maggie P. Fu, Donato Amodio, Issan Yee San Tam, Gavin Shueng Wai Chan, Ashish A. Sharma, Joshua Dalmann, Robin van der Lee, Géraldine Blanchard-Rohner, Susan Lin, Quentin Philippot, Phillip A. Richmond, Jessica J. Lee, Allison Matthews, Michael Seear, Alexandra K. Turvey, Rachael L. Philips, Terri F. Brown-Whitehorn, Christopher J. Gray, Kosuke Izumi, James R. Treat, Kathleen H. Wood, Justin Lack, Asya Khleborodova, Julie E. Niemela, Xingtian Yang, Rui Liang, Lin Kui, Christina Sze Man Wong, Grace Wing Kit Poon, Alexander Hoischen, Caspar I. van der Made, Jing Yang, Koon Wing Chan, Jaime Sou Da Rosa Duque, Pamela Pui Wah Lee, Marco Hok Kung Ho, Brian Hon Yin Chung, Huong Thi Minh Le, Wanling Yang, Pejman Rohani, Ali Fouladvand, Hassan Rokni-Zadeh, Majid Changi-Ashtiani, Mohammad Miryounesi, Anne Puel, Mohammad Shahrooei, Andrea Finocchi, Paolo Rossi, Beatrice Rivalta, Cristina Cifaldi, Antonio Novelli, Chiara Passarelli, Stefania Arasi, Dominique Bullens, Kate Sauer, Tania Claeys, Catherine M. Biggs, Emma C. Morris, Sergio D. Rosenzweig, John J. O’Shea, Wyeth W. Wasserman, H. Melanie Bedford, Clara D.M. van Karnebeek, Paolo Palma, Siobhan O. Burns, Isabelle Meyts, Jean-Laurent Casanova, Jonathan J. Lyons, Nima Parvaneh, Anh Thi Van Nguyen, Caterina Cancrini, Jennifer Heimall, Hanan Ahmed, Margaret L. McKinnon, Yu Lung Lau, Vivien Béziat, Stuart E. Turvey

Publikováno v: Journal of Experimental Medicine, 220
Journal of Experimental Medicine, 220, 5

STAT6 (signal transducer and activator of transcription 6) is a transcription factor that plays a central role in the pathophysiology of allergic inflammation. We have identified 16 patients from 10 families spanning three continents with a profound

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c287d6bde4f6efb981c86aed42d1504
https://hdl.handle.net/2066/290791

In support of point-of-care social needs screening: The effects of five social determinants on the health of children with chronic diseases in British Columbia

Autor: Michael Seear, Janis Dionne, Zachary Hamilton, Connie L. Yang, Alanna De Mello, Shazhan Amed, Bernardo Garcia Espinosa, Katherine Tourigny

Publikováno v: Paediatr Child Health

BACKGROUND: Prior to introducing social needs screening into our subspecialty clinics, we first wanted to understand the health effects of the major social challenges facing children with chronic diseases in British Columbia. METHODS: Using a strict

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd75e93d9a02551c5190b752cc1402b6
https://doi.org/10.1093/pch/pxy090

The importance of considering monogenic causes of autoimmunity: A somatic mutation in KRAS causing pediatric Rosai-Dorfman syndrome and systemic lupus erythematosus

Autor: Jefferson Terry, David A. Cabral, Kimberly Morishita, Robert J. Ragotte, Jaime Guzman, Kate L. Del Bel, Ross E. Petty, Julian Pleydell-Pearce, Margaret L. McKinnon, John K. Wu, Christof Senger, Julie S. Prendiville, Anita Dhanrajani, Stuart E. Turvey, Kelly L. Brown, Clara D.M. van Karnebeek, Lori B. Tucker, Jenny Tekano, Kristin Houghton, Maja Tarailo-Graovac, Michael Seear

Publikováno v: Clinical immunology (Orlando, Fla.), 175, 143-146. Academic Press Inc.

Objectives: Clinicians need to be aware of the growing list of defined monogenic etiologies of autoimmune diseases. This is particularly relevant when evaluating children, as these rare monogenic forms of autoimmunity tend to present very early in li

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89fe6b27d473202d39f09ef14adcaa73
https://doi.org/10.1016/j.clim.2016.12.006

A review of congenital lung malformations with a simplified classification system for clinical and research use

Autor: Douglas H. Jamieson, Michael Seear, Amy Hoepker, William Glomb, Patrick Daigneault, Deborah E. McFadden, Jennifer Townsend

Publikováno v: Pediatric surgery international. 33(6)

Congenital lung abnormalities are rare malformations increasingly detected early by prenatal ultrasound. Whether management of these frequently asymptomatic lesions should be surgical or conservative is an unresolved issue. The necessary prospective

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5176f5732e05f1396532944b119a3bc6
https://pubmed.ncbi.nlm.nih.gov/28204920