Zobrazeno 1 - 10
of 57
pro vyhledávání: '"Michael Schorpp"'
Autor:
Divine-Fondzenyuy Lawir, Cristian Soza-Ried, Norimasa Iwanami, Iliana Siamishi, Göran O. Bylund, Connor O´Meara, Katarzyna Sikora, Benoît Kanzler, Erik Johansson, Michael Schorpp, Pierre Cauchy, Thomas Boehm
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-5 (2024)
Externí odkaz:
https://doaj.org/article/9f3b2083209d4a00aba9271b904cbdaa
Autor:
Connor P. O’Meara, Lucia Guerri, Divine-Fondzenyuy Lawir, Fernando Mateos, Mary Iconomou, Norimasa Iwanami, Cristian Soza-Ried, Katarzyna Sikora, Iliana Siamishi, Orlando Giorgetti, Sarah Peter, Michael Schorpp, Thomas Boehm
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-3 (2024)
Externí odkaz:
https://doaj.org/article/2d9bbcca1e134054a0f3d0eb9b35b848
Autor:
Divine-Fondzenyuy Lawir, Cristian Soza-Ried, Norimasa Iwanami, Iliana Siamishi, Göran O. Bylund, Connor O´Meara, Katarzyna Sikora, Benoît Kanzler, Erik Johansson, Michael Schorpp, Pierre Cauchy, Thomas Boehm
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-18 (2024)
Abstract The stability of cellular phenotypes in developing organisms depends on error-free transmission of epigenetic and genetic information during mitosis. Methylation of cytosine residues in genomic DNA is a key epigenetic mark that modulates gen
Externí odkaz:
https://doaj.org/article/157305a4e0ba4667992f767ee78c7835
Publikováno v:
BMC Immunology, Vol 24, Iss 1, Pp 1-12 (2023)
Abstract Background The anglerfish, belonging to the teleost order Lophiiformes, are a diverse and species-rich group of fish that are known to exhibit a number of unique morphological, reproductive and immunological adaptations. Work to date has ide
Externí odkaz:
https://doaj.org/article/8f3be333bddb4ee69b1c130c61d2d04b
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-13 (2022)
Abstract The zinc finger transcription factor Ikaros1 (Ikzf1) is required for lymphoid development in mammals. Four zinc fingers constitute its DNA binding domain and two zinc fingers are present in the C-terminal protein interaction module. We descr
Externí odkaz:
https://doaj.org/article/5acda035ae074c24bfb31ec939d16d77
Autor:
Connor P. O’Meara, Lucia Guerri, Divine-Fondzenyuy Lawir, Fernando Mateos, Mary Iconomou, Norimasa Iwanami, Cristian Soza-Ried, Katarzyna Sikora, Iliana Siamishi, Orlando Giorgetti, Sarah Peter, Michael Schorpp, Thomas Boehm
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-18 (2021)
Abstract To capture the global gene network regulating the differentiation of immature T cells in an unbiased manner, large-scale forward genetic screens in zebrafish were conducted and combined with genetic interaction analysis. After ENU mutagenesi
Externí odkaz:
https://doaj.org/article/336c81ef888e42abb79749a16438e1dd
Autor:
Norimasa Iwanami, Divine-Fondzenyuy Lawir, Katarzyna Sikora, Connor O´Meara, Kohei Takeshita, Michael Schorpp, Thomas Boehm
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
Evidence for transgenerational inheritance of epigenetic information in vertebrates is scarce. Here the authors report that homozygous dnmt1 mutant zebrafish are essentially normal, with the exception of impaired lymphopoiesis, with impaired larval (
Externí odkaz:
https://doaj.org/article/42e0c083b91b47bbb72a34837b735ceb
Publikováno v:
Open Biology, Vol 11, Iss 2 (2021)
In vertebrates, the development of lymphocytes from undifferentiated haematopoietic precursors takes place in so-called primary lymphoid organs, such as the thymus. Therein, lymphocytes undergo a complex differentiation and selection process that cul
Externí odkaz:
https://doaj.org/article/965323086ee64b10bcaa736a41830406
Autor:
Norimasa Iwanami, Kohei Takeshita, Divine-Fondzenyuy Lawir, Isao Suetake, Shoji Tajima, Katarzyna Sikora, Inês Trancoso, Connor ÓMeara, Iliana Siamishi, Yousuke Takahama, Makoto Furutani-Seiki, Hisato Kondoh, Yasushige Yonezawa, Michael Schorpp, Thomas Boehm
Publikováno v:
iScience, Vol 23, Iss 7, Pp 101260- (2020)
Summary: DNA methylation is a universal epigenetic mechanism involved in regulation of gene expression and genome stability. The DNA maintenance methylase DNMT1 ensures that DNA methylation patterns are faithfully transmitted to daughter cells during
Externí odkaz:
https://doaj.org/article/9dc9bcf901e54e3d837b33f1a672b111
Autor:
Jeremy B. Swann, Annelies Weyn, Daisuke Nagakubo, Conrad C. Bleul, Atsushi Toyoda, Christiane Happe, Nikolai Netuschil, Isabell Hess, Annette Haas-Assenbaum, Yoshihito Taniguchi, Michael Schorpp, Thomas Boehm
Publikováno v:
Cell Reports, Vol 8, Iss 4, Pp 1184-1197 (2014)
The thymus is a lymphoid organ unique to vertebrates, and it provides a unique microenvironment that facilitates the differentiation of immature hematopoietic precursors into mature T cells. We subjected the evolutionary trajectory of the thymic micr
Externí odkaz:
https://doaj.org/article/ca82771736a049f9915b6f7d602cd395