Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Michael Schertzer"'
Autor:
Michael Schertzer, Laurent Jullien, André L. Pinto, Rodrigo T. Calado, Patrick Revy, Arturo Londoño-Vallejo
Publikováno v:
Cells, Vol 12, Iss 24, p 2798 (2023)
Regulator of TElomere Length Helicase 1 (RTEL1) is a helicase required for telomere maintenance and genome replication and repair. RTEL1 has been previously shown to participate in the nuclear export of small nuclear RNAs. Here we show that RTEL1 def
Externí odkaz:
https://doaj.org/article/4dad15806383433abf306aa44ac37893
Publikováno v:
2014 ASEE Annual Conference & Exposition Proceedings.
Autor:
Michael Schertzer, Arturo Londoño-Vallejo, Aaron Mendez-Bermudez, Michelle Debatisse, Mylène Perderiset, Karine Jamet, Geneviève Almouzni, Jing Ye, Nicolas Nottet, Eric Gilson, Stephane Koundrioukoff, Marie Josèphe Giraud-Panis, Macarena Mowinckel, Liudmyla Lototska, Agurtzane Irizar, Olivier Croce, Serge Bauwens, Mare Paule Teulade-Fichou
Publikováno v:
Molecular Cell
Molecular Cell, Elsevier, 2018, 70 (3), pp.449-461.e5. ⟨10.1016/j.molcel.2018.03.036⟩
Molecular Cell, 2018, 70 (3), pp.449-461.e5. ⟨10.1016/j.molcel.2018.03.036⟩
Molecular Cell, Elsevier, 2018, 70 (3), pp.449-461.e5. ⟨10.1016/j.molcel.2018.03.036⟩
Molecular Cell, 2018, 70 (3), pp.449-461.e5. ⟨10.1016/j.molcel.2018.03.036⟩
Summary Hard-to-replicate regions of chromosomes (e.g., pericentromeres, centromeres, and telomeres) impede replication fork progression, eventually leading, in the event of replication stress, to chromosome fragility, aging, and cancer. Our knowledg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73ce31d58e8e99c896076015a236ff9f
https://hal.archives-ouvertes.fr/hal-02104993
https://hal.archives-ouvertes.fr/hal-02104993
Publikováno v:
Proteins: Structure, Function, and Bioinformatics. 82:897-903
Several studies have recently shown that germline mutations in RTEL1, an essential DNA helicase involved in telomere regulation and DNA repair, cause Hoyeraal-Hreidarsson syndrome (HHS), a severe form of dyskeratosis congenita. Using original new sof
Publikováno v:
2015 ASEE Annual Conference and Exposition Proceedings.
Autor:
Arturo Londoño-Vallejo, Michael Schertzer, Florent Dingli, Patrick Revy, Tangui Le Guen, Mylène Perderiset, Barbara Bardoni, Damarys Loew, Jean-Pierre de Villartay, Karina Jouravleva
Publikováno v:
Nucleic Acids Research
Nucleic Acids Research, Oxford University Press, 2015, 43 (3), pp.1834-1847. ⟨10.1093/nar/gku1402⟩
Nucleic Acids Research, 2015, 43 (3), pp.1834-1847. ⟨10.1093/nar/gku1402⟩
Nucleic Acids Research, Oxford University Press, 2015, 43 (3), pp.1834-1847. 〈10.1093/nar/gku1402〉
Nucleic Acids Research, Oxford University Press, 2015, 43 (3), pp.1834-1847. ⟨10.1093/nar/gku1402⟩
Nucleic Acids Research, 2015, 43 (3), pp.1834-1847. ⟨10.1093/nar/gku1402⟩
Nucleic Acids Research, Oxford University Press, 2015, 43 (3), pp.1834-1847. 〈10.1093/nar/gku1402〉
Hoyeraal-Hreidarsson syndrome (HHS) is a severe form of Dyskeratosis congenita characterized by developmental defects, bone marrow failure and immunodeficiency and has been associated with telomere dysfunction. Recently, mutations in Regulator of Tel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b10c3063aa748cbc39ac5ff6297cce24
https://hal.sorbonne-universite.fr/hal-01278052
https://hal.sorbonne-universite.fr/hal-01278052
Autor:
Guilhem Faure, Patrick Revy, Michael Schertzer, Jose Arturo Londono Vallejo, Isabelle Callebaut
Publikováno v:
Proteins-Structure, Function and Bioinformatics
Proteins-Structure, Function and Bioinformatics, 2014, 82, pp.897-903
Proteins-Structure, Function and Bioinformatics, Wiley, 2014, 82, pp.897-903
HAL
Proteins-Structure, Function and Bioinformatics, 2014, 82, pp.897-903
Proteins-Structure, Function and Bioinformatics, Wiley, 2014, 82, pp.897-903
HAL
International audience; Several studies have recently shown that germline mutations in RTEL1, an essential DNA helicase involved in telomere regulation and DNA repair, cause Hoyeraal-Hreidarsson syndrome (HHS), a severe form of dyskeratosis congenita
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::61f0495e863ec0d8bca28851cee9554a
https://hal.science/hal-01002499
https://hal.science/hal-01002499
Autor:
Nancy Sawyer, Jennifer Mak, Catherine Blackwell, Jose B. Cibelli, Gabriela M. Baerlocher, Elizabeth A. Chavez, Mary Kay Francis, Michael D. West, Vincent J. Cristofalo, Robert Lanza, Peter M. Lansdorp, Michael Schertzer
Publikováno v:
Science. 288:665-669
The potential of cloning depends in part on whether the procedure can reverse cellular aging and restore somatic cells to a phenotypically youthful state. Here, we report the birth of six healthy cloned calves derived from populations of senescent do
Autor:
Zhuo Wang, Michael Schertzer, Noa Lamm, Olga Vladimirova, Yehuda Tzfati, Klaus H. Kaestner, Memet Aker, Jonathan Schug, Jayaraju Dheekollu, Paul M. Lieberman, Alan J. Fox, Galina Glousker, Orr-El Weizman, Zhong Deng, Aliah Molczan, Arturo Londoño-Vallejo
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 110(36)
Telomeres repress the DNA damage response at the natural chromosome ends to prevent cell-cycle arrest and maintain genome stability. Telomeres are elongated by telomerase in a tightly regulated manner to ensure a sufficient number of cell divisions t
Autor:
Tangui Le Guen, Gérard Couillault, Laetitia Gaillard, Jean Soulier, Capucine Picard, Jean-Pierre de Villartay, Fabien Touzot, Patrick Nitschke, Isabelle Callebaut, Arturo Londoño-Vallejo, Michael Schertzer, Nada Jabado, Alain Fischer, Mylène Perderiset, Wassila Carpentier, Patrick Revy, Laurent Jullien
Publikováno v:
Human Molecular Genetics
Human Molecular Genetics, 2013, 22 (16), pp.3239-3249. ⟨10.1093/hmg/ddt178⟩
Human Molecular Genetics, Oxford University Press (OUP), 2013, 22 (16), pp.3239-3249. ⟨10.1093/hmg/ddt178⟩
Human Molecular Genetics, Oxford University Press (OUP), 2013, 22 (16), pp.3239-3249. 〈10.1093/hmg/ddt178〉
Human Molecular Genetics, 2013, 22 (16), pp.3239-3249. ⟨10.1093/hmg/ddt178⟩
Human Molecular Genetics, Oxford University Press (OUP), 2013, 22 (16), pp.3239-3249. ⟨10.1093/hmg/ddt178⟩
Human Molecular Genetics, Oxford University Press (OUP), 2013, 22 (16), pp.3239-3249. 〈10.1093/hmg/ddt178〉
International audience; Hoyeraal-Hreidarsson syndrome (HHS), a severe variant of dyskeratosis congenita (DC), is characterized by early onset bone marrowfailure, immunodeficiency and developmental defects. Several factors involved in telomere length