Zobrazeno 1 - 10
of 156
pro vyhledávání: '"Michael Schaffer"'
Autor:
Santiago Viteri, Anna Minchom, Lyudmila Bazhenova, Sai‐Hong Ignatius Ou, Joshua M. Bauml, Scott A. Shell, Michael Schaffer, Junchen Gu, Jennifer B. Rose, Joshua C. Curtin, Parthiv Mahadevia, Nicolas Girard
Publikováno v:
Molecular Oncology, Vol 17, Iss 2, Pp 230-237 (2023)
Epidermal growth factor receptor (EGFR) exon 20 insertion mutations (ex20ins) account for ≤ 12% of all EGFR‐mutant nonsmall cell lung cancers. We analysed real‐world datasets to determine the frequency of ex20ins variants, and the ability of po
Externí odkaz:
https://doaj.org/article/c4da93c6b1ad420a85fa00e6dd68825d
Autor:
Arshi Arora, Maria Patra-Kneuer, Gaomei Chang, Christian Kuffer, Michael Grau, Myroslav Zapukhlyak, Derek Blair, Kristina Ilieva, Christina Heitmueller, Georg Lenz, Michael Schaffer, Diana Alvarez Arias
Publikováno v:
HemaSphere, Vol 7, p e69573fd (2023)
Externí odkaz:
https://doaj.org/article/5b7a11de9b4848fbbceabc8b3ef25f02
Autor:
Sriram Balasubramanian, Brendan Hodkinson, Stephen J. Schuster, Nathan H. Fowler, Judith Trotman, Georg Hess, Bruce D. Cheson, Michael Schaffer, Steven Sun, Sanjay Deshpande, Jessica Vermeulen, Gilles Salles, Ajay K. Gopal
Publikováno v:
Cancer Medicine, Vol 11, Iss 1, Pp 61-73 (2022)
Abstract Background The single‐arm DAWN trial (NCT01779791) of ibrutinib monotherapy in patients with relapsed/refractory follicular lymphoma (FL) showed an overall response rate (ORR) of 20.9% and a median response duration of 19.4 months. This bi
Externí odkaz:
https://doaj.org/article/8e668f1ebce046fb90165c45e83463d9
Autor:
David Soong, Jeran Stratford, Herve Avet-Loiseau, Nizar Bahlis, Faith Davies, Angela Dispenzieri, A. Kate Sasser, Jordan M. Schecter, Ming Qi, Chad Brown, Wendell Jones, Jonathan J. Keats, Daniel Auclair, Christopher Chiu, Jason Powers, Michael Schaffer
Publikováno v:
BMC Bioinformatics, Vol 21, Iss 1, Pp 1-18 (2020)
Abstract Background Cancer associated copy number variation (CNV) events provide important information for identifying patient subgroups and suggesting treatment strategies. Technical and logistical issues, however, make it challenging to accurately
Externí odkaz:
https://doaj.org/article/af944e282c83406ea5bcda2da8461142
Autor:
Jennifer E. Beane, Sarah A. Mazzilli, Joshua D. Campbell, Grant Duclos, Kostyantyn Krysan, Christopher Moy, Catalina Perdomo, Michael Schaffer, Gang Liu, Sherry Zhang, Hanqiao Liu, Jessica Vick, Samjot S. Dhillon, Suso J. Platero, Steven M. Dubinett, Christopher Stevenson, Mary E. Reid, Marc E. Lenburg, Avrum E. Spira
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
Bronchial premalignant lesions can potentially progress to lung squamous cell carcinoma. Here, the authors profile bronchial biopsies from high-risk smokers by RNA sequencing and identify four molecular subtypes of premalignant lesions and an immune
Externí odkaz:
https://doaj.org/article/0cf5153a221648e9910fbb6ff4aaf085
Autor:
Brendan P. Hodkinson, Michael Schaffer, Joshua D. Brody, Wojciech Jurczak, Cecilia Carpio, Dina Ben-Yehuda, Irit Avivi, Ann Forslund, Muhit Özcan, John Alvarez, Rob Ceulemans, Nele Fourneau, Anas Younes, Sriram Balasubramanian
Publikováno v:
Translational Oncology, Vol 14, Iss 1, Pp 100977- (2021)
We analyzed potential biomarkers of response to ibrutinib plus nivolumab in biopsies from patients with diffuse large B-cell lymphoma (DLBCL), follicular lymphoma (FL), and Richter's transformation (RT) from the LYM1002 phase I/IIa study, using progr
Externí odkaz:
https://doaj.org/article/91087acb7391463aae85c4eba847cc09
Autor:
Michael Schaffer, Shalini Chaturvedi, Cuc Davis, Jan de Jong, Regina Aquino, Yasuhiro Oki, Nele Fourneau, Anas Younes, Sriram Balasubramanian
Publikováno v:
Cancer Treatment and Research Communications, Vol 25, Iss , Pp 100235- (2020)
Introduction: This unplanned post-hoc analysis was based on data from the phase Ib DBL1002 study (NCT01569750) and evaluated the association between molecular biomarkers and clinical response to combined treatment with ibrutinib plus rituximab, cyclo
Externí odkaz:
https://doaj.org/article/b2f5466faf1f4f18be3bbf63e3e0de8a
Autor:
Natalie A. Manley, Eléonore Bayen, Tamara L. Braley, Jennifer Merrilees, Amy M. Clark, Bradley Zylstra, Michael Schaffer, Alexandre M. Bayen, Katherine L. Possin, Bruce L. Miller, A. Katrin Schenk, Stephen J. Bonasera
Publikováno v:
Alzheimer’s & Dementia: Translational Research & Clinical Interventions, Vol 6, Iss 1, Pp n/a-n/a (2020)
Abstract Introduction Informal caregiving is an essential element of health‐care delivery. Little data describes how caregivers structure care recipients’ lives and impact their functional status. Methods We performed observational studies of com
Externí odkaz:
https://doaj.org/article/ce90ef190b7846909650af2831102ccf
Autor:
Michael Di Maria, Leonard Seltz, Michael Schaffer, Scott Auerbach, Adel Younoszai, Jeffrey Darst, Lisa Howley
Publikováno v:
MedEdPORTAL, Vol 11 (2015)
Abstract Introduction Our pediatric residency program has transitioned from a daily noon conference to an academic half-day model in which educational topics are focused into half a day per week. Programs that have adopted this approach have reported
Externí odkaz:
https://doaj.org/article/899bfbffaff540348e24cd0ce325e23b
Autor:
Florence Schaffner, Naho Yokota, Tatiana Carneiro-Lobo, Maki Kitano, Michael Schaffer, G Mark Anderson, Barbara M Mueller, Charles T Esmon, Wolfram Ruf
Publikováno v:
PLoS ONE, Vol 8, Iss 4, p e61071 (2013)
Several markers identify cancer stem cell-like populations, but little is known about the functional roles of stem cell surface receptors in tumor progression. Here, we show that the endothelial protein C receptor (EPCR), a stem cell marker in hemato
Externí odkaz:
https://doaj.org/article/da8ef9bf849d4e15a8b22dd9631721d9