Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Michael Saeftel"'
Autor:
Oliver Liesenfeld, Iana Parvanova, Jens Zerrahn, Seong-Ji Han, Frederik Heinrich, Melba Muñoz, Frank Kaiser, Toni Aebischer, Thorsten Buch, Ari Waisman, Gaby Reichmann, Olaf Utermöhlen, Esther von Stebut, Friederike D von Loewenich, Christian Bogdan, Sabine Specht, Michael Saeftel, Achim Hoerauf, Maria M Mota, Stephanie Könen-Waisman, Stefan H E Kaufmann, Jonathan C Howard
Publikováno v:
PLoS ONE, Vol 6, Iss 6, p e20568 (2011)
Clearance of infection with intracellular pathogens in mice involves interferon-regulated GTPases of the IRG protein family. Experiments with mice genetically deficient in members of this family such as Irgm1(LRG-47), Irgm3(IGTP), and Irgd(IRG-47) ha
Externí odkaz:
https://doaj.org/article/5baf7e6b5cbb4c77a93f96997cbaf00b
Autor:
Michael Saeftel
Publikováno v:
hautnah dermatologie. 38:30-33
Publikováno v:
Deutsches Ärzteblatt Online.
Autor:
Hidayat Hussain, Barbara Schulz, Karsten Krohn, Sabine Specht, Salem Ramadan Sarite, Michael Saeftel, Achim Hoerauf
Publikováno v:
Journal of Medicinal Chemistry. 54:4913-4917
New phenazines were synthesized by oxygenation of 1- and 2-naphthol with transition metal peroxo complexes and in situ reaction with 1,2-diamines. The title compounds were evaluated for in vitro antimalarial activity against Plasmodium falciparum and
Autor:
Sabine Specht, Bettina Dubben, Elmar Endl, Achim Hoerauf, Daniel Fernandez Ruiz, Michael Saeftel, Susanne Deininger
Publikováno v:
Microbes and Infection. 11:172-180
Chronic helminth infections such as filariasis in human hosts can be life long, since parasites are equipped with a repertoire of immune evasion strategies. In many areas where helminths are prevalent, other infections such as malaria are co-endemic.
Autor:
Michael, Saeftel
Publikováno v:
Kinderkrankenschwester : Organ der Sektion Kinderkrankenpflege. 34(5)
Publikováno v:
Mini-Reviews in Medicinal Chemistry. 6:1231-1241
The increasing drug resistance of malaria parasites against chemotherapeutics enforces new strategies in finding new drugs. Here, we describe a new class of compounds the piperidone 3-carboxylates which show an antiplasmodial effect in vitro and in v
Autor:
Achim Hoerauf, Manuela Arndt, Michael Saeftel, Nancy A. Lee, Sabine Specht, Bettina Dubben, Elmar Endl, James J. Lee
Publikováno v:
Infection and Immunity. 74:5236-5243
Eosinophils are a hallmark of allergic diseases and helminth infection, yet direct evidence for killing of helminth parasites by their toxic granule products exists only in vitro. We investigated the in vivo roles of the eosinophil granule proteins e
Autor:
Ulrike Holzgrabe, Annette Kaiser, Ramadan Salem Sarite, Daniela Ulmer, Michael Saeftel, Achim Hoerauf, Tujo Njuguna
Publikováno v:
Parasitology Research. 99:281-286
The increasing resistance of the malaria parasites has enforced new strategies of finding new drug targets. We have isolated two genes involved in spermidine metabolism, encoding deoxyhypusine synthase (DHS) and eukaryotic initiation factor 5A (eIF-5
Autor:
Véronique Penlap Beng, Salem Ramadan Sarite, Victor Kuete, Hidayat Hussain, Augustin Ephram Nkengfack, Achim Hoerauf, Kenneth Oben Eyong, Michael Saeftel, Karsten Krohn, Gabriel N. Folefoc
Publikováno v:
Phytochemistry. 67:605-609
The study of the chemical constituents of the roots of Newbouldia laevis (Bignoniaceae) has resulted in the isolation and characterization of a naphthoquinone–anthraquinone coupled pigment named newbouldiaquinone A ( 1 ) together with 14 known comp