Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Michael S. Unger"'
Autor:
Michela Luciano, Helene Sieberer, Peter W. Krenn, Hieu-Hoa Dang, Julia Vetter, Theresa Neuper, Diana Amend, Constantin Blöchl, Christian X. Weichenberger, Anna Eglseer, Michael S. Unger, Ancuela Andosch, Philip Steiner, Daniel Neureiter, Renate Bauer, Laura Hummer, Suzana Tesanovic, Stephanie Binder, Dominik P. Elmer, Helen Strandt, Susanne Schaller, Dirk Strunk, Lisa Pleyer, Richard Greil, Stephan Winkler, Tanja N. Hartmann, Dirk Schmidt-Arras, Christian G. Huber, Fritz Aberger, Jutta Horejs-Hoeck
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-14 (2024)
Abstract Background Acute myeloid leukemia (AML) is characterized by the abnormal proliferation of myeloid precursor cells and presents significant challenges in treatment due to its heterogeneity. Recently, the NLRP3 inflammasome has emerged as a po
Externí odkaz:
https://doaj.org/article/4d77e7ab0fdf4883bc818ffc7dd4f0d8
Autor:
Tobias Frauenlob, Theresa Neuper, Christof Regl, Veronika Schaepertoens, Michael S. Unger, Anna-Lena Oswald, Hieu-Hoa Dang, Christian G. Huber, Fritz Aberger, Silja Wessler, Jutta Horejs-Hoeck
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Helicobacter pylori is a widespread Gram-negative pathogen involved in a variety of gastrointestinal diseases, including gastritis, ulceration, mucosa-associated lymphoid tissue (MALT) lymphoma and gastric cancer. Immune responses aimed at eradicatio
Externí odkaz:
https://doaj.org/article/cb89368a84c4480bafb6c997f752a220
Autor:
Diana M. Bessa de Sousa, Rodolphe Poupardin, Saul A. Villeda, Adam B. Schroer, Thomas Fröhlich, Vanessa Frey, Wolfgang Staffen, Heike Mrowetz, Barbara Altendorfer, Michael S. Unger, Bernhard Iglseder, Bernhard Paulweber, Eugen Trinka, Janne Cadamuro, Martin Drerup, Katharina Schallmoser, Ludwig Aigner, Kathrin M. Kniewallner
Publikováno v:
Frontiers in Molecular Biosciences, Vol 10 (2023)
Introduction: Alzheimer’s disease (AD) and aging are associated with platelet hyperactivity. However, the mechanisms underlying abnormal platelet function in AD and aging are yet poorly understood.Methods: To explore the molecular profile of AD and
Externí odkaz:
https://doaj.org/article/636238625d2e475984b6becd06a2383c
Autor:
Katharina Strempfl, Michael S. Unger, Stefanie Flunkert, Andrea Trost, Herbert A. Reitsamer, Birgit Hutter-Paier, Ludwig Aigner
Publikováno v:
Biomolecules, Vol 12, Iss 3, p 346 (2022)
Parkinson’s disease (PD) and dementia with Lewy bodies (DLB) are two common types of α-synucleinopathies and represent a high unmet medical need. Despite diverging clinical manifestations, both neurodegenerative diseases share several facets of th
Externí odkaz:
https://doaj.org/article/1cd98421cb934ffd97049176fa95cf40
Autor:
Kathrin M. Kniewallner, Diana M. Bessa de Sousa, Michael S. Unger, Heike Mrowetz, Ludwig Aigner
Publikováno v:
Frontiers in Neuroscience, Vol 14 (2020)
Alzheimer’s disease (AD) is a neurodegenerative disease with a complex and not fully understood pathogenesis. Besides brain-intrinsic hallmarks such as abnormal deposition of harmful proteins, i.e., amyloid beta in plaques and hyperphosphorylated T
Externí odkaz:
https://doaj.org/article/c3bdc0a3dca64a5896a8cb97e5060cc5
Autor:
Diana M. Bessa de Sousa, Ariane Benedetti, Barbara Altendorfer, Heike Mrowetz, Michael S. Unger, Katharina Schallmoser, Ludwig Aigner, Kathrin Maria Kniewallner
Publikováno v:
Aging. 15:630-649
Autor:
Douglas Galasko, Hamilton Oh, Andreas Keller, Tobias Fehlmann, Tony Wyss-Coray, Kathleen L. Poston, Michael S. Unger, Emma Tapp, David Gate, Tim J. Nonninger, Katharina Strempfl, Divya Channappa, Victor W. Henderson, Andrew C. Yang, Ludwig Aigner, Olivia Leventhal, Mark M. Davis, Marian Shahid
Publikováno v:
Science. 374:868-874
Autoimmunity in Lewy body dementia Lewy body dementia (LBD) is a brain disease that leads to progressive decline in thinking, movement, and independent function. It results from the build-up of microscopic deposits called Lewy bodies, which develop f
Autor:
Michael S. Unger, Nicolas Singewald, Maria Kharitonova, Christoph Schwarzer, Susanne A. Wolf, Helmut Kettenmann, Sinead Rooney, Simone B. Sartori, Ludwig Aigner, Anupam Sah
Publikováno v:
Translational Psychiatry, Vol 10, Iss 1, Pp 1-10 (2020)
Translational Psychiatry
Translational Psychiatry
High trait anxiety is a substantial risk factor for developing anxiety disorders and depression. While neuroinflammation has been identified to contribute to stress-induced anxiety, little is known about potential dysregulation in the neuroinflammato
Autor:
Eliezer Masliah, Birgit Hutter-Paier, Katharina Strempfl, Miriam Holztrattner, Julia Garnweidner-Raith, Michael S. Unger, Nadine Pillichshammer, Thomas K. Felder, Edward Rockenstein, Johannes Attems, Julia Marschallinger, Iris Leister, Mary Johnson, Barbara Altendorfer, Mansoor Chishty, Ludwig Aigner
Publikováno v:
Neurotherapeutics
Dementia with Lewy bodies (DLB) represents a huge medical need as it accounts for up to 30% of all dementia cases, and there is no cure available. The underyling spectrum of pathology is complex and creates a challenge for targeted molecular therapie
Autor:
Mark B. De Los Santos, Divya Channappa, Anthony D. Wagner, Michael S. Unger, David Gate, Tony Wyss-Coray, Fanny M. Elahi, Mark M. Davis, Olivia Leventhal, Michael D. Greicius, Andrew C. Yang, Alisha McBride, Yongha Kim, Benoit Lehallier, Douglas Galasko, Ludwig Aigner, Grace Tam, Naresha Saligrama, John V. Pluvinage, Kelly Chen, Jinte Middeldorp
Publikováno v:
Nature
Signal Transduction and Targeted Therapy
Signal Transduction and Targeted Therapy
Alzheimer’s disease is an incurable neurodegenerative disorder in which neuroinflammation has a critical function1. However, little is known about the contribution of the adaptive immune response in Alzheimer’s disease2. Here, using integrated an