Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Michael S. Serfas"'
Autor:
Michael S. Serfas, Medeia Gartel, Eugene Goufman, Andrei L. Gartel, Gen Sheng Wu, Wafik S. El-Deiry, Angela L. Tyner
Publikováno v:
Experimental Cell Research. 227:171-181
We examined the relationship between expression of the p21 (WAF1/CIP1) inhibitor of cyclin-dependent kinases, cessation of proliferation, and terminal differentiation in the epithelia of the gastrointestinal tract. Using in situ hybridization, we per
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e503632e2ddbfca3eaae3fd02031d16
https://doi.org/10.1006/excr.1996.0264
https://doi.org/10.1006/excr.1996.0264
Autor:
Sean B. Carroll, Michael S Serfas
Publikováno v:
Developmental biology. 287(2)
Butterflies produce complex and diverse wing patterns by mechanisms that are generally unknown. We have employed a pharmacological approach to explore the molecular mechanisms of pattern formation. In a screen of over 200 compounds injected into deve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65368f77e7fdb918b29187bbef4ff13d
https://pubmed.ncbi.nlm.nih.gov/16216238
https://pubmed.ncbi.nlm.nih.gov/16216238
A novel p21WAF1/CIP1 transcript is highly dependent on p53 for its basal expression in mouse tissues
Publikováno v:
Oncogene. 23(49)
p21WAF1/CIP1 is an important transcriptional target of p53 and it plays a critical role in growth arrest after DNA damage. Here, we report the identification of a novel alternate mouse p21 transcript that is conserved in evolution. It differs from th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::189d5c580c9f7fc75b49b42dd4d90447
https://pubmed.ncbi.nlm.nih.gov/15361845
https://pubmed.ncbi.nlm.nih.gov/15361845
Autor:
Robert D. Reed, Michael S Serfas
Publikováno v:
Current biology : CB. 14(13)
In butterflies there is a class of "intervein" wing patterns that have lines of symmetry halfway between wing veins. These patterns occur in a range of shapes, including eyespots, ellipses, and midlines, and were proposed to have evolved through deve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82627722e7d90ace4bb464b6e1878d0f
https://pubmed.ncbi.nlm.nih.gov/15324685
https://pubmed.ncbi.nlm.nih.gov/15324685
Publikováno v:
The Journal of biological chemistry. 278(32)
Liver injury and repair were examined in wild type, p21Waf1/Cip1, and p27Kip1-deficient mice following carbon tetrachloride (CCl4) administration. In wild type liver, p21 expression is induced in a biphasic manner following injection of CCl4, with an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d963946a19bb6d6bd55a299abf5211cf
https://pubmed.ncbi.nlm.nih.gov/12759355
https://pubmed.ncbi.nlm.nih.gov/12759355
Autor:
Michael S. Serfas, Angela L. Tyner
Publikováno v:
Oncology research. 13(6-10)
The tyrosine kinases Brk/PTK6/Sik, Srm, Frk/Rak/Gtk/Iyk/Bsk, and Src42A/Dsrc41 have a low degree of sequence homology to other known kinases, including one another. We show here that the exon structure of these kinases, which we will call the Brk fam
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1dc62ef9b9074c801917ba234f1910bc
https://pubmed.ncbi.nlm.nih.gov/12725532
https://pubmed.ncbi.nlm.nih.gov/12725532
Autor:
Michael S. Serfas, Angela L. Tyner
Publikováno v:
Oncogene. 17(26)
Ryk is a ubiquitously expressed tyrosine kinase-like receptor of unknown activity and associations. We examined ryk expression in adult mouse epithelial tissues and during embryonic development at the histological level. Ryk RNA is present at greatly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a56550a4d57ce54322a2edfe3494b8c
https://pubmed.ncbi.nlm.nih.gov/10030667
https://pubmed.ncbi.nlm.nih.gov/10030667
Publikováno v:
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.). 213(2)
Progression through the cell cycle is regulated by cyclins and cyclin-dependent kinases (Cdks). The cyclin kinase inhibitor p21 (also known as WAF1, CIP1, SDI1, and MDA-6) can induce G1 arrest and block entry into S phase by inactivating Cdks or by i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c96411c90570e254757b98a928718e5
https://pubmed.ncbi.nlm.nih.gov/8931660
https://pubmed.ncbi.nlm.nih.gov/8931660
Publikováno v:
Tumor Biology ISBN: 9783642647352
The signal transduction pathways that regulate the regeneration of the mammalian intestinal epithelium are not well understood. To identify tyrosine kinases involved in regulating the continuous proliferation and cell differentiation, we amplified th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8a770761e00f6a7d598e85e13e282b4b
https://doi.org/10.1007/978-3-642-61180-3_28
https://doi.org/10.1007/978-3-642-61180-3_28
Publikováno v:
Gastroenterology. 118:A921
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::85cad5b8bdbfc7b35ed685fefa99199b
https://doi.org/10.1016/s0016-5085(00)85821-7
https://doi.org/10.1016/s0016-5085(00)85821-7