Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Michael S. Placzek"'
Autor:
Michael S. Placzek, Daniel K. Wilton, Michel Weïwer, Mariah A. Manter, Sarah E. Reid, Christopher J. Meyer, Arthur J. Campbell, Besnik Bajrami, Antoine Bigot, Sarah Bricault, Agathe Fayet, Arnaud Frouin, Frederick Gergits, Mehak Gupta, Wei Jiang, Michelle Melanson, Chiara D. Romano, Misha M. Riley, Jessica M. Wang, Hsiao-Ying Wey, Florence F. Wagner, Beth Stevens, Jacob M. Hooker
Publikováno v:
ACS Central Science, Vol 10, Iss 5, Pp 1105-1114 (2024)
Externí odkaz:
https://doaj.org/article/5385c7c9d35c443787ef32334e8917b9
Autor:
Yu Lan, Ping Bai, Zude Chen, Ramesh Neelamegam, Michael S. Placzek, Hao Wang, Stephanie A. Fiedler, Jing Yang, Gengyang Yuan, Xiying Qu, Hayden R. Schmidt, Jinchun Song, Marc D. Normandin, Chongzhao Ran, Changning Wang
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 9, Iss 6, Pp 1204-1215 (2019)
The sigma-1 receptor (σ1R) is a unique intracellular protein. σ1R plays a major role in various pathological conditions in the central nervous system (CNS), implicated in several neuropsychiatric disorders. Imaging of σ1R in the brain using positr
Externí odkaz:
https://doaj.org/article/6f8047a7f7314da6b2b69e01ff50ae50
Autor:
Ping Bai, Sha Bai, Michael S. Placzek, Xiaoxia Lu, Stephanie A. Fiedler, Brenda Ntaganda, Hsiao-Ying Wey, Changning Wang
Publikováno v:
Molecules, Vol 25, Iss 5, p 1018 (2020)
The orexin receptor (OX) is critically involved in motivation and sleep−wake regulation and holds promising therapeutic potential in various mood disorders. To further investigate the role of orexin receptors (OXRs) in the living human brain and to
Externí odkaz:
https://doaj.org/article/172764069a7f46e4aef0af8b1cec3d5d
Autor:
Benjamin H. Rotstein PhD, Michael S. Placzek PhD, Hema S. Krishnan PhD, Aleksandra Pekošak MPharm, Thomas Lee Collier PhD, Changning Wang PhD, Steven H. Liang PhD, Ethan S. Burstein PhD, Jacob M. Hooker PhD, Neil Vasdev PhD
Publikováno v:
Molecular Imaging, Vol 15 (2016)
Activation of retinoid X receptors (RXRs) has been proposed as a therapeutic mechanism for the treatment of neurodegeneration, including Alzheimer's and Parkinson's diseases. We previously reported radiolabeling of a Food and Drug Administration-appr
Externí odkaz:
https://doaj.org/article/725b84346084474882a75638559914f5
Autor:
Ciprian Catana, Jeungchan Lee, Roberta Sclocco, Robert R. Edwards, Oluwaseun Akeju, Jacob M. Hooker, Yi Zhang, Julie C. Price, Angel Torrado-Carvajal, Michael S. Placzek, Vitaly Napadow, Ludovica Brusaferri, Erin Morrissey, Daniel S. Albrecht, Atreyi Saha, Minhae Kim, Marco L. Loggia, Zeynab Alshelh, Paulina Knight
Publikováno v:
Brain
We recently showed that patients with different chronic pain conditions (such as chronic low back pain, fibromyalgia, migraine and Gulf War illness) demonstrated elevated brain and/or spinal cord levels of the glial marker 18-kDa translocator protein
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5b61882df0f2ff2a449922fde732fbf
https://doi.org/10.1093/brain/awab336
https://doi.org/10.1093/brain/awab336
Autor:
Michael S, Placzek
Publikováno v:
Handbook of experimental pharmacology. 271
Kappa opioid receptor (KOR) neuroimaging using positron emission tomography (PET) has been immensely successful in all phases of discovery and validation in relation to radiotracer development from preclinical imaging to human imaging. There are now
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::31e15000bc47acafcdd933cc463397b4
https://pubmed.ncbi.nlm.nih.gov/34363128
https://pubmed.ncbi.nlm.nih.gov/34363128
Autor:
Jing Yang, Ramesh Neelamegam, Jinchun Song, Gengyang Yuan, Ping Bai, Chongzhao Ran, Marc D. Normandin, Changning Wang, Michael S. Placzek, Zude Chen, Hayden R. Schmidt, Stephanie A. Fiedler, Hao Wang, Yu Lan, Xiying Qu
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 9, Iss 6, Pp 1204-1215 (2019)
Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica. B
The sigma-1 receptor (σ1R) is a unique intracellular protein. σ1R plays a major role in various pathological conditions in the central nervous system (CNS), implicated in several neuropsychiatric disorders. Imaging of σ1R in the brain using positr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6a5701aa32f8f8afaa0cf073ac28afc
https://doi.org/10.1016/j.apsb.2019.07.002
https://doi.org/10.1016/j.apsb.2019.07.002
Autor:
Michael S. Placzek
Publikováno v:
The Kappa Opioid Receptor ISBN: 9783030890735
Kappa opioid receptor (KOR) neuroimaging using positron emission tomography (PET) has been immensely successful in all phases of discovery and validation in relation to radiotracer development from preclinical imaging to human imaging. There are now
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::002f7142261320cf1465da48c69afebb
https://doi.org/10.1007/164_2021_498
https://doi.org/10.1007/164_2021_498
Autor:
Sarah Nesti, Benjamin Larimer, Frank Dubois, Michael S. Placzek, Jacob M. Hooker, Massimo Loda, Umar Mahmood, Emily G. Bloch, Giorgia Zadra
Publikováno v:
Journal of Nuclear Medicine. 59:1538-1543
Tremendous efforts are currently dedicated to the development of novel therapies targeting the androgen receptor (AR), the major driver of prostate cancer disease and its progression to castration resistance. The ability to noninvasively interrogate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ad25a4325b7684aa3cecb224bebcd190
https://doi.org/10.2967/jnumed.118.208785
https://doi.org/10.2967/jnumed.118.208785
Autor:
Jacob M. Hooker, Zhen Chen, Jing Yang, Chongzhao Ran, Hema S. Krishnan, Neil Vasdev, Kenneth Dahl, Steven H. Liang, E. Livni, Vidya Narayanaswami, Thomas Lee Collier, Vadim Bernard-Gauthier, Michael S. Placzek
Publikováno v:
Molecular Pharmaceutics. 15:695-702
Dyshomeostasis or abnormal accumulation of metal ions such as copper, zinc, and iron have been linked to the pathogenesis of multiple neurodegenerative disorders including Alzheimer’s disease (AD) and Huntington’s disease (HD). 5,7-Dichloro-2-((d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2d78f07f56c13d9341e880850e702a46
https://doi.org/10.1021/acs.molpharmaceut.7b00936
https://doi.org/10.1021/acs.molpharmaceut.7b00936