Zobrazeno 1 - 10
of 125
pro vyhledávání: '"Michael S. Middleton"'
Autor:
Ghattas J. Malki, Nidhi P. Goyal, Patricia Ugalde-Nicalo, Lauren F. Chun, Jasen Zhang, Ziyi Ding, Yingjia Wei, Cynthia Knott, Danielle Batakis, Walter Henderson, Claude B. Sirlin, Michael S. Middleton, Jeffrey B. Schwimmer
Publikováno v:
Metab Syndr Relat Disord
Metabolic syndrome and related disorders, vol 21, iss 4
Metabolic syndrome and related disorders, vol 21, iss 4
Background: Pediatric studies have shown associations between hepatic steatosis and total body fat, visceral fat, and lean mass. However, these associations have not been assessed simultaneously, leaving their relative importance unknown. Objective:
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::362db071bcf09ecf366faadcaf70dde6
https://europepmc.org/articles/PMC10181799/
https://europepmc.org/articles/PMC10181799/
Autor:
Guilherme M, Cunha, Timoteo I, Delgado, Michael S, Middleton, Sam, Liew, Walter C, Henderson, Danielle, Batakis, Kang, Wang, Rohit, Loomba, Ryan S, Huss, Robert P, Myers, Claude B, Sirlin, Kathryn J, Fowler, Kyle A, Hasenstab
Publikováno v:
American Journal of Roentgenology. 219:224-232
Autor:
Marybeth A. Nedrud, Mohammad Chaudhry, Michael S. Middleton, Cynthia A. Moylan, Reginald Lerebours, Sheng Luo, Alfredo Farjat, Cynthia Guy, Rohit Loomba, Manal F. Abdelmalek, Claude B. Sirlin, Mustafa R. Bashir
Publikováno v:
Radiology. 306
Background Several early-phase clinical trials for the treatment of nonalcoholic steatohepatitis (NASH) use liver fat content as measured with the MRI-derived proton density fat fraction (PDFF) for a primary outcome. These trials have shown relative
Autor:
An Tang, Bogdan Dzyubak, Meng Yin, Alexandra Schlein, Walter C. Henderson, Jonathan C. Hooker, Timoteo I. Delgado, Michael S. Middleton, Lin Zheng, Tanya Wolfson, Anthony Gamst, Rohit Loomba, Richard L. Ehman, Claude B. Sirlin
Publikováno v:
European radiology, vol 32, iss 5
Abstract Objectives To assess reproducibility and fibrosis classification accuracy of magnetic resonance elastography (MRE)–determined liver stiffness measured manually at two different centers, and by automated analysis software in adults with non
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::490101570b25d648ca9440d0f800c78d
https://escholarship.org/uc/item/3hw3g0cw
https://escholarship.org/uc/item/3hw3g0cw
Autor:
Michael S. Middleton, Jennifer Y Cui, Kathryn J. Fowler, Jeffrey B. Schwimmer, Rohit Loomba, Cheng William Hong, Alexandra Schlein, Tanya Wolfson, Yang Xu, Claude B. Sirlin, Lindsey M. Negrete, Anthony Gamst, Gavin Hamilton, Danielle N. Batakis
Publikováno v:
Abdom Radiol (NY)
PURPOSE: To evaluate repeatability of ROI sampling strategies for quantifying hepatic proton density fat fraction (PDFF) and to assess error relative to the 9-ROI PDFF. METHODS: This was a secondary analysis in subjects with known or suspected nonalc
Autor:
Mark Bydder, Andrew T. Trout, Takeshi Yokoo, Mark Smith, Houchun H. Hu, Claude B. Sirlin, Timothy J. Colgan, Thomas L. Chenevert, Yunhong Shu, Michael S. Middleton, Jean A. Tkach, Jean H. Brittain, Scott B. Reeder, Suraj D. Serai, Ruvini Navaratna, Ruiyang Zhao, Gavin Hamilton, Mustafa R. Bashir, Diego Hernando, Walter C. Henderson, Dariya I. Malyarenko
Publikováno v:
Magnetic Resonance in Medicine. 86:69-81
Purpose Chemical shift-encoded MRI (CSE-MRI) is well-established to quantify proton density fat fraction (PDFF) as a quantitative biomarker of hepatic steatosis. However, temperature is known to bias PDFF estimation in phantom studies. In this study,
Autor:
Cynthia Knott, Michael S. Middleton, Elizabeth L. Yu, Martina Wallace, Claude B. Sirlin, Bruce A. Barshop, Jon A. Gangoiti, Nidhi Goyal, Mary Catherine Sawh, Noah Meurs, Alexandra Schlein, Jeffrey B. Schwimmer, Jivani M. Gengatharan, Janis Durelle, Craig Bross, Christian M. Metallo, Emma Shapiro, Kimberly P. Newton
Publikováno v:
Journal of Pediatric Gastroenterology & Nutrition. 72:e90-e96
Objectives We sought to evaluate the relevance of pediatric dairy fat recommendations for children at risk for nonalcoholic fatty liver disease (NAFLD) by studying the association between dairy fat intake and the amount of liver fat. The effects of d
Autor:
Wei Shen, Michael S. Middleton, Guilherme M. Cunha, Timoteo I. Delgado, Tanya Wolfson, Anthony Gamst, Kathryn J. Fowler, Adina Alazraki, Andrew T. Trout, Michael A. Ohliger, Shetal N. Shah, Mustafa R. Bashir, David E. Kleiner, Rohit Loomba, Brent A. Neuschwander-Tetri, Arun J. Sanyal, Jane Zhou, Claude B. Sirlin, Joel E. Lavine
Publikováno v:
Journal of hepatology.
Non-alcoholic steatohepatitis (NASH) is prevalent in adults with obesity and can progress to cirrhosis. In a secondary analysis of prospectively acquired data from the multicenter, randomized, placebo-controlled FLINT trial, we investigated the relat
Autor:
Claude B. Sirlin, Meng Yin, Kang Wang, Michael S. Middleton, Scott B. Reeder, Jonathan Hooker, Ethan Z. Sy, Kathryn J. Fowler, Adrija Mamidipalli, Jeffrey B. Schwimmer, Bin Song, Jun Chen, Yingzhen N. Zhang, Kevin J. Glaser, Rohit Loomba, Yali Qu, Tanya Wolfson, Richard L. Ehman, Yesenia Covarrubias, Mark A. Valasek, Anthony Gamst
Publikováno v:
European radiology, vol 31, iss 11
Eur Radiol
Eur Radiol
To investigate associations between histology and hepatic mechanical properties measured using multiparametric magnetic resonance elastography (MRE) in adults with known or suspected nonalcoholic fatty liver disease (NAFLD) without histologic fibrosi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::216c0e6208a7754d73edc8b32d0fccea
https://escholarship.org/uc/item/3nj2r5dj
https://escholarship.org/uc/item/3nj2r5dj
Autor:
Eric Lawitz, G. Mani Subramanian, Zeid Kayali, Edward Gane, Mazen Noureddin, Vincent Wai-Sun Wong, Jun Xu, Stephen A. Harrison, Sergio Rojter, Eliza Harting, Mary E. Rinella, Robert Herring, C. Stephen Djedjos, Robert P. Myers, James F. Trotter, Saumya Jayakumar, Chuhan Chung, Magdy Elkhashab, Keyur Patel, Susan Greenbloom, Andrew N. Billin, Mitchell L. Shiffman, Michael S. Middleton, Bradley Freilich
Publikováno v:
Hepatology. 72:58-71
Background and aims We evaluated the safety and efficacy of cilofexor (formerly GS-9674), a small-molecule nonsteroidal agonist of farnesoid X receptor, in patients with nonalcoholic steatohepatitis (NASH). Approach and results In this double-blind,