Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Michael S. McQueney"'
Autor:
Stephen Flowers, Brenda A. Petronella, Michael S. McQueney, Barbara Fanelli, Warren Eisenberg, Albert Uveges, Allison L. Roden, Scott Salowe, Venu Bommireddy, Jeffrey J. Letourneau, Chia-Yu Huang, James R. Beasley
Publikováno v:
PLoS ONE, Vol 19, Iss 8 (2024)
Externí odkaz:
https://doaj.org/article/0bc393e9a5eb4fc4b54f7a26e7689763
Autor:
Henry M. Sarau, Feng Wang, Gerald E. Hunsberger, Elizabeth A. Capper-Spudich, Ralph A. Rivero, James J. Foley, Yonghui Wang, Zheng Yang, Laura S. Fisher, Todd L. Graybill, Michael S. McQueney, Jian Jin, Widdowson Katherine L, Zining Wu, Dulcie B. Schmidt, Terence J. Kiesow, Jakob Busch-Petersen
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 19:114-118
A series of N-arylpiperazine camphor sulfonamides was discovered as novel CXCR3 antagonists. The synthesis, structure–activity relationships, and optimization of the initial hit that resulted in the identification of potent and selective CXCR3 anta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff022de9cf3c289d1a821663993332c2
https://doi.org/10.1016/j.bmcl.2008.11.008
https://doi.org/10.1016/j.bmcl.2008.11.008
Autor:
Michael S. McQueney, Roy A. Johanson, Elizabeth A. Capper-Spudich, Josephine H. Fox, Patricia L. Podolin, John J. Peterson, Robert W. Marquis, Edit Kurali, T. Gregg Davis, Dennis S. Yamashita, Stephen M. LoCastro, Gerald J. Terfloth, Brian R. Smith, Donald C. Carpenter, Edward Long, Xiaoyang Dong, Brian Bolognese
Publikováno v:
The Journal of Immunology. 180:7989-8003
Members of the papain family of cysteine proteases (cathepsins) mediate late stage processing of MHC class II-bound invariant chain (Ii), enabling dissociation of Ii, and binding of antigenic peptide to class II molecules. Recognition of cell surface
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88df259ac244132f833d3d9196e414fd
https://doi.org/10.4049/jimmunol.180.12.7989
https://doi.org/10.4049/jimmunol.180.12.7989
Autor:
Cynthia L. Burns-Kurtis, Josephine H. Fox, Saul Needle, Elizabeth A. Capper, Anne M. Romanic, Alan R. Olzinski, Michael S. McQueney, Fiona M. Kelly
Publikováno v:
Cardiovascular Research. 62:610-620
Objective: Neointimal development following balloon angioplasty involves many factors including smooth muscle cell (SMC) migration and proliferation and extracellular matrix (ECM) remodeling. Further, in hypercholesterolemic (HC) conditions, there is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0046019e7f2d11d03156306ee7dc3824
https://doi.org/10.1016/j.cardiores.2004.02.002
https://doi.org/10.1016/j.cardiores.2004.02.002
Publikováno v:
SLAS Discovery. 8:712-715
Undecaprenyl pyrophosphate synthase (UPPS) catalyzes the consecutive condensation of 8 molecules of isopentenyl pyrophosphate with farnesyl pyrophosphate to yield C55-undecaprenyl pyrophosphate, which is required for bacterial cell wall synthesis. UP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fd2fa44283aa11c257adc35bf25721ee
https://doi.org/10.1177/1087057103258185
https://doi.org/10.1177/1087057103258185
Autor:
Maxine Gowen, Catherine J. Gress, Shing Mei Hwang, Michael W. Lark, Michael S. McQueney, Ian E. James, Robert W. Marquis, Simon M. Blake, Ru Yu, Daniel F. Veber, Hye-Ja Oh, Denise Zembryki, Thaddeus A. Tomaszek, Dennis S. Yamashita
Publikováno v:
Journal of Biological Chemistry. 276:11507-11511
Cathepsins K and L are related cysteine proteases that have been proposed to play important roles in osteoclast-mediated bone resorption. To further examine the putative role of cathepsin L in bone resorption, we have evaluated selective and potent i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::892b89bfe824acabaf8fa273601f5802
https://doi.org/10.1074/jbc.m010684200
https://doi.org/10.1074/jbc.m010684200
Autor:
Ward W. Smith, Thaddeus A. Tomaszek, Cheryl A. Janson, Baoguang Zhao, Mark Alan Levy, Dennis S. Yamashita, Sherin S. Abdel-Meguid, Ru Yu, Yen Jack Hwekwo, Daniel F. Veber, Scott K. Thompson, Thomas Joseph Carr, Robert W. Marquis, Karla J. D'Alessio, Carl F. Ijames, Michael S. McQueney, Hye-Ja Oh
Publikováno v:
Bioorganic & Medicinal Chemistry. 7:581-588
Cathepsin K (EC 3.4.22.38) is a cysteine protease of the papain superfamily which is selectively expressed within the osteoclast. Several lines of evidence have pointed to the fact that this protease may play an important role in the degradation of t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::982f16a2419ee5ecc999e28f282ce276
https://doi.org/10.1016/s0968-0896(99)00011-5
https://doi.org/10.1016/s0968-0896(99)00011-5
Autor:
Karen M. Anderson, Michael S. McQueney, Sabine Rouanet, Marie Chabot-fletcher, Isabelle Berrebi-Bertrand, Robert B. Kirkpatrick, David C. Underwood
Publikováno v:
Journal of Molecular and Cellular Cardiology. 31:705-719
The predominant response of the heart to sustained increased work load is development of ventricular hypertrophy, principally as a result of hypertrophy of cardiomyocytes. The molecular mechanisms and factors involved in cardiomyocyte hypertrophy are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c35a100f288845770ecedc1048e21a29
https://doi.org/10.1006/jmcc.1998.0903
https://doi.org/10.1006/jmcc.1998.0903
Autor:
Kimberly A. Brun, Karla J. D'Alessio, Michael S. McQueney, Michael J. Orsini, Christine Debouck
Publikováno v:
Protein Expression and Purification. 15:213-220
We have constructed and optimized a high yielding Escherichia coli expression system to produce glycosylation-free human procathepsin K and have developed conditions for refolding this enzyme. Recombinant human procathepsin K (EC 3.4.22.38) was expre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::752be93e3027295c8c35786555e2f60a
https://doi.org/10.1006/prep.1998.1013
https://doi.org/10.1006/prep.1998.1013
Autor:
Bernard Y. Amegadzie, Christopher Jones, Kannan Ramachandran, Michael S. McQueney, Fred H. Drake, Charles R. Hanning, Janice R. Connor, John A. Feild, Kimberly A. Brun
Publikováno v:
Protein Expression and Purification. 14:387-394
Methodology for the production of recombinant active cynomolgus monkey (Macaca fascicularis) cathepsin K (EC 3.4.22.38) was elucidated. The cDNA encoding the cathepsin K was cloned from female M. cynomolgus monkey mRNA. The deduced amino acid sequenc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12037d5962dde077a5353cc0594ab801
https://doi.org/10.1006/prep.1998.0965
https://doi.org/10.1006/prep.1998.0965