Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Michael S. Manak"'
Autor:
Wendell R. Su, Robert J. Saphirstein, Brad J. Hogan, Grannum R. Sant, Thiagarajan Meyyappan, Andrew Min, Delaney Berger, Ashok C. Chander, Nikhil Joshi, Matthew J. Whitfield, Michael S. Manak, Nicolai Steinke, Kevin B. Knopf, Gauri Dixit, Hui-May Chu, Jonathan S. Varsanik, David M. Albala
The risk stratification of prostate cancer and breast cancer tumours from patients relies on histopathology, selective genomic testing, or on other methods employing fixed formalin tissue samples. However, static biomarker measurements from bulk fixe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::163d36a5e0a411eb41eea5ebb8bfc0be
https://europepmc.org/articles/PMC6407716/
https://europepmc.org/articles/PMC6407716/
Autor:
David M. Albala, Hani Rashid, Ashok C. Chander, Stephen M. Zappala, Naveen Kella, Jonathan S. Varsanik, Ene Ette, Grannum R. Sant, Vladimir Mouraviev, Michael S. Manak, Kimberly M. Rieger-Christ
Publikováno v:
Urology. 124
Objective To examine the ability of a novel live primary-cell phenotypic (LPCP) test to predict postsurgical adverse pathology (P-SAP) features and risk stratify patients based on SAP features in a blinded study utilizing radical prostatectomy (RP) s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ce492b4bb283a9fede8d85fa2d2ca76
https://pubmed.ncbi.nlm.nih.gov/30312670
https://pubmed.ncbi.nlm.nih.gov/30312670
Autor:
Travis Sullivan, Delaney Berger, Wendell R. Su, Naveen Kella, Vladimir Mouraviev, Kevin B. Knopf, Grannum R. Sant, Gauri Dixit, Ashok C. Chander, Kimberly M. Rieger-Christ, Matthew J. Whitfield, David M. Albala, Jonathan S. Varsanik, Hani Rashid, Stephen M. Zappala, Michael S. Manak, Brad J. Hogan, Mani Foroohar
Publikováno v:
Journal of Urology. 195
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bba32c72128e1449237435e4f6498860
https://doi.org/10.1016/j.juro.2016.02.2220
https://doi.org/10.1016/j.juro.2016.02.2220
Autor:
Ashok C. Chander, Jonathan S. Varsanik, Grannum R. Sant, Michael S. Manak, Brad J. Hogan, Kevin B. Knopf
Publikováno v:
Molecular Cancer Research. 16:A31-A31
Largely due to tumor heterogeneity, risk stratification of patients diagnosed with ductal carcinoma in situ (DCIS) of the breast remains a significant challenge. Management of DCIS is also problematic as we wish to personalize treatment of a patient
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2c5e3c855d414a4909aae463a96ae5ad
https://doi.org/10.1158/1557-3125.advbc17-a31
https://doi.org/10.1158/1557-3125.advbc17-a31
Autor:
Said Movahedi Naini, Maria H.J. van Osch, Sander van den Heuvel, Jagesh V. Shah, Geert J. P. L. Kops, Dirk M. Hentschel, Monique van der Voet, John R. Yates, Michael S. Manak, Ian McLeod, Andrea G. Brear
Publikováno v:
Journal of Cell Science. 123:1623-1633
Error-free chromosome segregation depends on timely activation of the multi-subunit E3 ubiquitin ligase APC/C. Activation of the APC/C initiates chromosome segregation and mitotic exit by targeting critical cell-cycle regulators for destruction. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55ef2381a7c829c7ee0bf2aef85193b8
https://doi.org/10.1242/jcs.061549
https://doi.org/10.1242/jcs.061549
Autor:
Panagis Filippakopoulos, Meera Soundararajan, Jagesh V. Shah, Quinn Deveraux, Michael S. Manak, Taebo Sim, Nicholas Kwiatkowski, David Pellman, Hwan Geun Choi, Mijung Kwon, Nannette Jelluma, Nathanael S. Gray, Geert J. P. L. Kops, Stefan Knapp, Sabine Rottmann
Publikováno v:
Nature chemical biology
Mps1, a dual-specificity kinase, is required for the proper functioning of the spindle assembly checkpoint and the maintenance of chromosomal stability. As Mps1 function has been implicated in numerous phases of the cell cycle, it is expected the dev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51e1428face01a546b9d1b16f8e813cf
https://doi.org/10.1038/nchembio.345
https://doi.org/10.1038/nchembio.345
Autor:
Michael S. Manak, Robert J. Ferl
Publikováno v:
Biochemistry. 46:1055-1063
Oscillations in cellular divalent cation concentrations are key events that can trigger signal transduction cascades. Common cellular divalent cations, such as calcium and magnesium, interact with 14-3-3 proteins. The metal ion interaction causes a c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::506753a09d739898a4a0d611ddd68098
https://doi.org/10.1021/bi061366c
https://doi.org/10.1021/bi061366c
Autor:
Hani Rashid, Kimberly M. Rieger-Christ, Michael S. Manak, Andrew Min, Ashok C. Chander, Mani Foroohar, Delaney Berger, Matthew J. Whitfield, Wendell R. Su, Kevin B. Knopf, Brad J. Hogan, Vladimir Mouraviev, Travis Sullivan, Jonathan S. Varsanik, Ray Hernandez, Naveen Kella, David M. Albala, Grannum R. Sant
Publikováno v:
Journal of Urology. 193
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::de596670e9f1d2865d9fa7872597afe5
https://doi.org/10.1016/j.juro.2015.02.182
https://doi.org/10.1016/j.juro.2015.02.182
Publikováno v:
Journal of Molecular Catalysis A: Chemical. 160:145-156
The AM1-calculated partial oxygen charge of several phenoxide anions, potential ligands for tungsten-based classical catalytic systems for olefin metathesis, has been used as an indication of their electronwithdrawing ability. Based on the modeled se
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4a9e43a47da296bbb0e38ae8b4feb857
https://doi.org/10.1016/s1381-1169(00)00241-7
https://doi.org/10.1016/s1381-1169(00)00241-7
Autor:
Hani Rashid, Mani Foroohar, Kimberly M. Rieger-Christ, Gauri Dixit, Jonathan S. Varsanik, Brad J. Hogan, Wendell R. Su, Delaney Berger, Vladimir Mouraviev, Michael S. Manak, Grannum R. Sant, Travis Sullivan, David M. Albala, Stephen M. Zappala, Naveen Kella, Ashok C. Chander, Matthew J. Whitfield, Kevin B. Knopf
Publikováno v:
Journal of Clinical Oncology. 34:338-338
338 Background: A novel tissue based biomarker panel is introduced to objectively assess disease aggressiveness and invasive potential of Prostate Cancer (CaP). The biomarker diagnostic platform incorporates both molecular and phenotypic data that ma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::44472c0a72aa6994baadfc96342472b8
https://doi.org/10.1200/jco.2016.34.2_suppl.338
https://doi.org/10.1200/jco.2016.34.2_suppl.338