Zobrazeno 1 - 10
of 105
pro vyhledávání: '"Michael S. Kallos"'
Autor:
Breanna S. Borys, Tiffany Dang, Hannah Worden, Leila Larijani, Jessica M. Corpuz, Brett D. Abraham, Emilie J. Gysel, Julia Malinovska, Roman Krawetz, Tamas Revay, Bob Argiropoulos, Derrick E. Rancourt, Michael S. Kallos, Sunghoon Jung
Publikováno v:
Stem Cell Research & Therapy, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract Background While pluripotent stem cell (PSC) therapies move toward clinical and commercial applications at a rapid rate, manufacturing reproducibility and robustness are notable bottlenecks in regulatory approval. Therapeutic applications of
Externí odkaz:
https://doaj.org/article/2db8d01dfcf348088a43dc9d70f85a86
Autor:
Hayley M. Todesco, Chris Gafuik, Cini M. John, Erin L. Roberts, Breanna S. Borys, Alexis Pawluk, Michael S. Kallos, Kyle G. Potts, Douglas J. Mahoney
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 32, Iss 1, Pp 101189- (2024)
The severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) pandemic highlighted the importance of vaccine innovation in public health. Hundreds of vaccines built on numerous technology platforms have been rapidly developed against SARS-CoV-2 si
Externí odkaz:
https://doaj.org/article/fdb3ab36b00a41dab43e9dd75f45b765
Autor:
Nerea Cuesta-Gomez, Kevin Verhoeff, Nidheesh Dadheech, Tiffany Dang, Ila Tewari Jasra, Mario Bermudez de Leon, Rena Pawlick, Braulio Marfil-Garza, Perveen Anwar, Haide Razavy, Patricio Adrián Zapata-Morin, Glen Jickling, Aducio Thiesen, Doug O’Gorman, Michael S. Kallos, A. M. James Shapiro
Publikováno v:
Stem Cell Research & Therapy, Vol 14, Iss 1, Pp 1-24 (2023)
Abstract Background Induced pluripotent stem cells (iPSCs) offer potential to revolutionize regenerative medicine as a renewable source for islets, dopaminergic neurons, retinal cells, and cardiomyocytes. However, translation of these regenerative ce
Externí odkaz:
https://doaj.org/article/871ddb8a83944edb9407894503394516
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 6, p 5152 (2023)
Regenerative therapies for the treatment of peripheral nerve and spinal cord injuries can require hundreds of millions of autologous cells. Current treatments involve the harvest of Schwann cells (SCs) from nerves; however, this is an invasive proced
Externí odkaz:
https://doaj.org/article/30531c4853604a5fa2137076e32e524a
Autor:
Breanna S. Borys, Tiffany Dang, Tania So, Leili Rohani, Tamas Revay, Tylor Walsh, Madalynn Thompson, Bob Argiropoulos, Derrick E. Rancourt, Sunghoon Jung, Yas Hashimura, Brian Lee, Michael S. Kallos
Publikováno v:
Stem Cell Research & Therapy, Vol 12, Iss 1, Pp 1-19 (2021)
Abstract Background Human induced pluripotent stem cells (hiPSCs) hold enormous promise in accelerating breakthroughs in understanding human development, drug screening, disease modeling, and cell and gene therapies. Their potential, however, has bee
Externí odkaz:
https://doaj.org/article/2bc815c68c614342b30ff70eac6b8561
Autor:
Breanna S. Borys, Tania So, James Colter, Tiffany Dang, Erin L. Roberts, Tamas Revay, Leila Larijani, Roman Krawetz, Ian Lewis, Bob Argiropoulos, Derrick E. Rancourt, Sunghoon Jung, Yas Hashimura, Brian Lee, Michael S. Kallos
Publikováno v:
Stem Cells Translational Medicine, Vol 9, Iss 9, Pp 1036-1052 (2020)
Abstract Human induced pluripotent stem cells (hiPSCs) have generated a great deal of attention owing to their capacity for self‐renewal and differentiation into the three germ layers of the body. Their discovery has facilitated a new era in biomed
Externí odkaz:
https://doaj.org/article/12cda13c70c14445b8dbe352327b75a7
Publikováno v:
Engineering Reports, Vol 3, Iss 12, Pp n/a-n/a (2021)
Abstract Peripheral nerve and spinal cord injuries affect millions of people worldwide often leading to lifelong disability and pain. Cell therapy using autologous Schwann cells are currently being investigated for the treatment of these injuries and
Externí odkaz:
https://doaj.org/article/29bd43df03cb4986b7a491909ba9ce64
Autor:
Boaz Arzi, Tracy L. Webb, Thomas G. Koch, Susan W. Volk, Dean H. Betts, Ashlee Watts, Laurie Goodrich, Michael S. Kallos, Amir Kol
Publikováno v:
Frontiers in Veterinary Science, Vol 8 (2021)
In the past decade, the potential to translate scientific discoveries in the area of regenerative therapeutics in veterinary species to novel, effective human therapies has gained interest from the scientific and public domains. Translational researc
Externí odkaz:
https://doaj.org/article/0ee4d38c900944a58bb75e8aa05dfc52
Autor:
Erin L. Roberts, Tiffany Dang, Sarah I. M. Lepage, Amir Hamed Alizadeh, Tylor Walsh, Thomas G. Koch, Michael S. Kallos
Publikováno v:
Journal of Biological Engineering, Vol 13, Iss 1, Pp 1-16 (2019)
Abstract Equine mesenchymal stromal cells (MSCs) are increasingly investigated for their clinical therapeutic utility. Such cell-based treatments can require cell numbers in the millions or billions, with conventional expansion methods using static T
Externí odkaz:
https://doaj.org/article/a2640560a5154563afa31db56fe355b7
Autor:
Brian Lee, Sunghoon Jung, Yas Hashimura, Maximilian Lee, Breanna S. Borys, Tiffany Dang, Michael S. Kallos, Carlos A. V. Rodrigues, Teresa P. Silva, Joaquim M. S. Cabral
Publikováno v:
Bioengineering, Vol 9, Iss 3, p 92 (2022)
Allogeneic cell therapy products, such as therapeutic cells derived from pluripotent stem cells (PSCs), have amazing potential to treat a wide variety of diseases and vast numbers of patients globally. However, there are various challenges related to
Externí odkaz:
https://doaj.org/article/47483c05b1ef4895932fffd080a3c19e