Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Michael S. Glennon"'
Autor:
Soumojit Pal, Benjamin R. Nixon, Michael S. Glennon, Puneeth Shridhar, Sidney L. Satterfield, Yan Ru Su, Jason R. Becker
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 10, Iss 15 (2021)
Background Sarcomere gene mutations lead to cardiomyocyte hypertrophy and pathological myocardial remodeling. However, there is considerable phenotypic heterogeneity at both the cellular and the organ level, suggesting modifiers regulate the effects
Externí odkaz:
https://doaj.org/article/c83c0c927fd940fda6359ec45d2963bb
Autor:
Lyssa Y. Baker, Chelsea R. Hobby, Andrew W. Siv, William C. Bible, Michael S. Glennon, Derek M. Anderson, Steven J. Symes, David K. Giles
Publikováno v:
BMC Microbiology, Vol 18, Iss 1, Pp 1-12 (2018)
Abstract Background Pseudomonas aeruginosa, a common opportunistic pathogen, is known to cause infections in a variety of compromised human tissues. An emerging mechanism for microbial survival is the incorporation of exogenous fatty acids to alter t
Externí odkaz:
https://doaj.org/article/276be20f8de84621a87a61c67d7994af
Autor:
Hind Lal, Qinkun Zhang, Beth Weber, Sidney L. Satterfield, Guy Salama, Michael S Glennon, Jason R Becker, Soumojit Pal, Eric J Hall, Puneeth Shridhar
Publikováno v:
Cardiovasc Res
Aims The cardiac natriuretic peptides (atrial natriuretic peptide [ANP] and B-type natriuretic peptide [BNP]) are important regulators of cardiovascular physiology, with reduced natriuretic peptide (NP) activity linked to multiple human cardiovascula
Autor:
Michael S Glennon, Michael L. Freeman, Emily S. Kounlavong, Jason R Becker, Eric J. Hall, Sara C. Sebag, Benjamin R. Nixon
Publikováno v:
The FASEB Journal. 33:1138-1150
Raf1/c-Raf is a well-characterized serine/threonine-protein kinase that links Ras family members with the MAPK/ERK signaling cascade. We have identified a novel splice isoform of human Raf1 that causes protein truncation and loss of the C-terminal ki
Publikováno v:
Journal of the American College of Cardiology. 77:844
Autor:
Hind Lal, Jason R Becker, Prachi Umbarkar, Anand P Singh, Ghermes Chilov, Michael S Glennon, Qinkun Zhang
Publikováno v:
Circulation Research. 125
Background: The advent of tyrosine kinase inhibitor (TKI) targeted therapy revolutionized the treatment of chronic myelogenous leukemia (CML) patients, leading to a significant impact on remission rates and overall survival. However, cardiotoxicity a
Autor:
Thomas Force, Manisha Gupte, Qinkun Zhang, Cristi L. Galindo, Anand Prakash Singh, Michael S Glennon, Prachi Umbarkar, Jason R Becker, Hind Lal
Aims Tyrosine kinase inhibitors (TKIs) have revolutionized the treatment of chronic myelogenous leukaemia (CML). However, cardiotoxicity of these agents remains a serious concern. The underlying mechanism of these adverse cardiac effects is largely u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::678a1b98af98279a79e4e9c350c942a2
https://europepmc.org/articles/PMC6452321/
https://europepmc.org/articles/PMC6452321/
Abstract 361: Analysis of Cardiotoxic Mechanisms Associated With Tyrosine Kinase Inhibitor Ponatinib
Autor:
Jason R Becker, Anand P Singh, Qinkun Zhang, Prachi Umbarkar, Thomas Force, Manisha Gupte, Cristi L. Galindo, Michael S Glennon, Hind Lal
Publikováno v:
Circulation Research. 123
Background: Ponatinib, a potent pan-BCR-ABL tyrosine kinase inhibitor (TKI) holds significant promise in the treatment of chronic myelogenous leukemia (CML), although the potential cardiotoxicity of this agent remains a concern. In order to overcome
Autor:
Steven J. K. Symes, David K. Giles, Andrew W. Siv, Chelsea R. Hobby, Michael S. Glennon, Derek M. Anderson, Lyssa Y. Baker, William C. Bible
Publikováno v:
BMC Microbiology
BMC Microbiology, Vol 18, Iss 1, Pp 1-12 (2018)
BMC Microbiology, Vol 18, Iss 1, Pp 1-12 (2018)
Background Pseudomonas aeruginosa, a common opportunistic pathogen, is known to cause infections in a variety of compromised human tissues. An emerging mechanism for microbial survival is the incorporation of exogenous fatty acids to alter the cell
Autor:
Sara C. Sebag, Alejandro De Feria, Benjamin R. Nixon, H. Scott Baldwin, Michael S Glennon, Jason R Becker, Alexandra F. Williams
It remains unclear how perturbations in cardiomyocyte sarcomere function alter postnatal heart development. We utilized murine models that allowed manipulation of cardiac myosin-binding protein C (MYBPC3) expression at critical stages of cardiac onto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1fb76367ec4ecb5cb0d0b27e7765915
https://europepmc.org/articles/PMC5313062/
https://europepmc.org/articles/PMC5313062/