Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Michael S. Dickens"'
Autor:
Michael S. Dickens, Richard N. Hill, Alan M. Goldberg, Robert A. Scala, Kevin J. Renskers, Stephen D. Gettings, David Brusick, Oliver P. Flint, N.L. Wilcox, Sidney Green, Robert L. Lipnick, Bellina Veronesi, June A. Bradlaw, John M. Frazier, Rodger Curren
Publikováno v:
In Vitro Cellular & Developmental Biology - Animal. 29:688-692
The development and application of in vitro alternatives designed to reduce or replace the use of animals, or to lessen the distress and discomfort of laboratory animals, is a rapidly developing trend in toxicology. However, at present there is no fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4e9995ad68ec5712e13a90146806c75
https://doi.org/10.1007/bf02631424
https://doi.org/10.1007/bf02631424
Autor:
Kevin J. Renskers, Dmitri Ptchelintsev, Michael S. Dickens, Stephen Pennisi, Manton Frierson, Gilles Klopman
Publikováno v:
Alternatives to Laboratory Animals. 21:14-27
The Multiple Computer Automated Structure Evaluation (Multi-CASE) methodology was applied to the semi-quantitative analysis of eye irritation potential of 186 organic chemicals. The resulting expert dictionary of substructural attributes indicates th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f927f65374bde1e2d033cffb28465327
https://doi.org/10.1177/026119299302100104
https://doi.org/10.1177/026119299302100104
Autor:
Kevin J. Renskers, S.D. Gettings, Michael S. Dickens, Robert L. Lipnick, Richard N. Hill, N.L. Wilcox, June A. Bradlaw, Oliver P. Flint, John M. Frazier, Sidney Green, D. Brusick, R. D. Curren, Alan M. Goldberg, R. A. Scala, Bellina Veronesi
Publikováno v:
Xenobiotica. 23:563-572
The development and application of in vitro alternatives designed to reduce or replace the use of animals, or to lessen the distress and discomfort of laboratory animals, is a rapidly developing trend in toxicology. However, at present there is no fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d00da9d8874db08d87dbf4f337ad0e80
https://doi.org/10.3109/00498259309059395
https://doi.org/10.3109/00498259309059395
Autor:
Robert L. Lipnick, Kevin J. Renskers, Bellina Veronesi, Michael S. Dickens, Robert A. Scala, Richard N. Hill, Oliver Flint, Stephen D. Gettings, June A. Bradlaw
Publikováno v:
Journal of the American College of Toxicology. 12:23-30
In toxicology the development and application of in vitro alternatives to reduce or replace animal testing, or to lessen the distress and discomfort of laboratory animals, is a rapidly developing trend. However, at present there is no formal administ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e748b9c7c9d66e2966af257349aba271
https://doi.org/10.3109/10915819309140619
https://doi.org/10.3109/10915819309140619
Autor:
Virginia C. Gordon, Janice J. Teal, Kyle T. Smith, Laura H. Hearn, Francis H. Kruszewski, Michael S. Dickens
Publikováno v:
Alternatives to Laboratory Animals. 20:146-163
465 cosmetic product formulations and raw ingredients were evaluated with the EYTEX™ system to determine the potential of this in vitro alternative for identifying eye irritation potential. The EYTEX™ system is a non-animal, biochemical procedure
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::33914ad51019369b30cb0563218fcf87
https://doi.org/10.1177/026119299202000120
https://doi.org/10.1177/026119299202000120
Publikováno v:
Alternatives to Laboratory Animals. 20:563-564
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cb4e4b0f840e1f9a59913a0f52540556
https://doi.org/10.1177/026119299202000408
https://doi.org/10.1177/026119299202000408
Autor:
Sam Sorof, Michael S. Dickens
Publikováno v:
Biochemical and Biophysical Research Communications. 79:713-719
Twenty-four hrs after i.p. administration of 3H-3-methylcholanthrene (3H-MCA) to 8–10 weeks old virgin or 14 days pregnant BALB c mice, the macromolecules and 3H-hydrocarbon-protein complexes in their mammary cytosols were extensively resolved acco
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f204dc12c606b34f761ad37b3f60b26
https://doi.org/10.1016/0006-291x(77)91170-6
https://doi.org/10.1016/0006-291x(77)91170-6
Publikováno v:
Biochemical and biophysical research communications. 67(4)
The induction of TMP synthetase activity in Tetrahymena pyriformis depended upon growth conditions. Enzymatic activity was low in cells grown in complex medium, and was high in cells grown in, or shifted to, defined medium. TMP synthetase activity ro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43b48b6a502c7ae5275d1d50d06e769c
https://pubmed.ncbi.nlm.nih.gov/173339
https://pubmed.ncbi.nlm.nih.gov/173339
Autor:
Sam Sorof, Michael S. Dickens
Publikováno v:
Nature. 285(5766)
Specific hormones1,2 in concert with epidermal growth factor3 induce the mouse mammary gland in serum-free whole organ culture to undergo two physiological cycles3, each consisting of lobuloalveolar development, differentiation and involution (regres
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4ed295b903f4a5f0c46b56f45d4cfc8
https://pubmed.ncbi.nlm.nih.gov/6772960
https://pubmed.ncbi.nlm.nih.gov/6772960