Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Michael S. D. Kormann"'
Autor:
Franziska Zeyer, Benedikt Mothes, Clara Will, Melanie Carevic, Jennifer Rottenberger, Bernd Nürnberg, Dominik Hartl, Rupert Handgretinger, Sandra Beer-Hammer, Michael S D Kormann
Publikováno v:
PLoS ONE, Vol 13, Iss 5, p e0197705 (2018)
[This corrects the article DOI: 10.1371/journal.pone.0154001.].
Externí odkaz:
https://doaj.org/article/969cec584ecb44ee82fd3de49e3f3fdb
Autor:
Michael S D Kormann, Alexander Dewerth, Felizitas Eichner, Praveen Baskaran, Andreas Hector, Nicolas Regamey, Dominik Hartl, Rupert Handgretinger, Justin S Antony
Publikováno v:
PLoS ONE, Vol 12, Iss 8, p e0183526 (2017)
Cystic Fibrosis (CF) is the most common monogenic disease among people of Western European descent and caused by mutations in the CFTR gene. However, the disease severity is immensely variable even among patients with similar CFTR mutations due to th
Externí odkaz:
https://doaj.org/article/2110c9c0729d433c8a0eeaf7724b213e
Autor:
Franziska Zeyer, Benedikt Mothes, Clara Will, Melanie Carevic, Jennifer Rottenberger, Bernd Nürnberg, Dominik Hartl, Rupert Handgretinger, Sandra Beer-Hammer, Michael S D Kormann
Publikováno v:
PLoS ONE, Vol 11, Iss 4, p e0154001 (2016)
Asthma is the most common chronic disease in childhood. Although several therapeutic options are currently available to control the symptoms, many drugs have significant side effects and asthma remains an incurable disease. Microbial exposure in earl
Externí odkaz:
https://doaj.org/article/beeaad1c81c6423880f268e6c4e20117
Autor:
Andrés Lamsfus-Calle, Alberto Daniel-Moreno, Justin S. Antony, Thomas Epting, Lukas Heumos, Praveen Baskaran, Jakob Admard, Nicolas Casadei, Ngadhnjim Latifi, Darina M. Siegmund, Michael S. D. Kormann, Rupert Handgretinger, Markus Mezger
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
β-hemoglobinopathies are caused by abnormal or absent production of hemoglobin in the blood due to mutations in the β-globin gene (HBB). Imbalanced expression of adult hemoglobin (HbA) induces strong anemia in patients suffering from the disease. H
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doajarticles::e6e99b97fba607dc7af4f1dc59c9e7f7
http://link.springer.com/article/10.1038/s41598-020-66309-x
http://link.springer.com/article/10.1038/s41598-020-66309-x
Autor:
Akm Ashiqul, Haque, Petra, Weinmann, Sumit, Biswas, Rupert, Handgretinger, Markus, Mezger, Michael S D, Kormann, Justin S, Antony
Publikováno v:
Bio Protoc
The mRNA therapeutics is a new class of medicine to treat many various diseases. However, in vitro transcribed (IVT) mRNA triggers immune responses due to recognition by human endosomal and cytoplasmic RNA sensors, but incorporation of modified nucle
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::cfd56de6a334575c658b8d83e504e46b
https://pubmed.ncbi.nlm.nih.gov/33855105
https://pubmed.ncbi.nlm.nih.gov/33855105
Autor:
Andreas Hector, Michael S D Kormann, Ines Mack, Philipp Latzin, Carmen Casaulta, Elisabeth Kieninger, Zhe Zhou, Ali Ö Yildirim, Alexander Bohla, Nikolaus Rieber, Matthias Kappler, Barbara Koller, Ernst Eber, Olaf Eickmeier, Stefan Zielen, Oliver Eickelberg, Matthias Griese, Marcus A Mall, Dominik Hartl
Publikováno v:
PLoS ONE, Vol 6, Iss 9, p e24399 (2011)
The chitinase-like protein YKL-40 was found to be increased in patients with severe asthma and chronic obstructive pulmonary disease (COPD), two disease conditions featuring neutrophilic infiltrates. Based on these studies and a previous report indic
Externí odkaz:
https://doaj.org/article/974f913beaa247739194b9b92771c333
Autor:
Andrés, Lamsfus-Calle, Alberto, Daniel-Moreno, Justin S, Antony, Thomas, Epting, Lukas, Heumos, Praveen, Baskaran, Jakob, Admard, Nicolas, Casadei, Ngadhnjim, Latifi, Darina M, Siegmund, Michael S D, Kormann, Rupert, Handgretinger, Markus, Mezger
Publikováno v:
Scientific Reports
β-hemoglobinopathies are caused by abnormal or absent production of hemoglobin in the blood due to mutations in the β-globin gene (HBB). Imbalanced expression of adult hemoglobin (HbA) induces strong anemia in patients suffering from the disease. H
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8e686d274106854e9365942592ff3a74
https://pubmed.ncbi.nlm.nih.gov/32576837
https://pubmed.ncbi.nlm.nih.gov/32576837
Publikováno v:
Molecular Therapy
Protein supplementation therapy using in vitro-transcribed (IVT) mRNA for genetic diseases contains huge potential as a new class of therapy. From the early ages of synthetic mRNA discovery, a great number of studies showed the versatile use of IVT m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7aeaa29d48c845aa5f98921e63a21380
Publikováno v:
J Biomed Mater Res B Appl Biomater
Membranes are an integral component of guided bone regeneration protocols. This pre-clinical study was aimed at enhancing the bioactivity of collagen membranes by incorporating plasmid DNA (pDNA) or chemically modified RNA (cmRNA) encoding bone morph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0550ae98df3026888314c0d2267e4bec
https://pubmed.ncbi.nlm.nih.gov/30466196
https://pubmed.ncbi.nlm.nih.gov/30466196
Autor:
A. K. M. Ashiqul Haque, Matthew H. Porteus, Krist T. Azizian, Sriram Vaidyanathan, Anton P. McCaffrey, Sabrina Shore, Michael S. D. Kormann, Ayal Hendel, Richard I. Hogrefe, Jordana M. Henderson, Justin S. Antony
Publikováno v:
Molecular Therapy. Nucleic Acids
Molecular Therapy-Nucleic Acids
Molecular Therapy: Nucleic Acids, Vol 12, Iss, Pp 530-542 (2018)
Molecular Therapy-Nucleic Acids
Molecular Therapy: Nucleic Acids, Vol 12, Iss, Pp 530-542 (2018)
The Cas9/guide RNA (Cas9/gRNA) system is commonly used for genome editing. mRNA expressing Cas9 can induce innate immune responses, reducing Cas9 expression. First-generation Cas9 mRNAs were modified with pseudouridine and 5-methylcytosine to reduce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51010ec6a713bfa68fb7ca7248c7c0a0
https://pubmed.ncbi.nlm.nih.gov/30195789
https://pubmed.ncbi.nlm.nih.gov/30195789