Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Michael S. Ching"'
Autor:
Kent Garrett, Anne McGrath, Andrew G. Ellis, Michael S Ching, P. T. Zeglinski, The‐Phung To, Jane Booth
Publikováno v:
Journal of Pharmacy Practice and Research. 44:89-94
Background Metaraminol 10 mg/mL injection is often diluted with sodium chloride 0.9% and pre-drawn into syringes by anaesthetists for use in the management of intraoperative hypotensive crisis. The 10 mg/mL ampoule presentation poses a significant sa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9e2876d422461a311f96b10377613dc9
https://doi.org/10.1002/jppr.1009
https://doi.org/10.1002/jppr.1009
Publikováno v:
Journal of Pharmacy Practice and Research. 40:101-105
Background: Despite the uncertainty regarding flucloxacillin's stability, flucloxacillin solutions are routinely used as 24-hour ambulatory infusions for hospital-in-the-home patients. Aim: To determine the stability of flucloxacillin solutions in a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e249c4c39e83890b08b282b685b285e7
https://doi.org/10.1002/j.2055-2335.2010.tb00515.x
https://doi.org/10.1002/j.2055-2335.2010.tb00515.x
Autor:
David C. M. Kong, Michael S Ching, The‐Phung To, Alan D Shilson, Andrew G. Ellis, Kent Garrett
Publikováno v:
Journal of Pharmacy Practice and Research. 38:219-222
Background N-acetylcysteine is used as prophylaxis to prevent contrast-induced nephropathy. Aim To investigate the stability of a formulated N-acetylcysteine capsule for prevention of contrast-induced nephropathy. Method Gelatine capsules containing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8ea0ba5c06a900c11a1ed346ee907bd7
https://doi.org/10.1002/j.2055-2335.2008.tb00843.x
https://doi.org/10.1002/j.2055-2335.2008.tb00843.x
Autor:
Denis J. Morgan, Henri Tochon-Danguy, John I. Sachinidis, Andrew M. Scott, Peter W Angus, Paul R. Froomes, Michael S. Ching, Hany Ghabrial
Publikováno v:
Nuclear Medicine and Biology. 30:93-100
Measurement of hepatic sinusoidal permeability of oxygen and other substrates may help elucidate the mechanisms responsible for impaired liver function in cirrhosis. However studies of sinusoidal oxygen permeability in normal liver and various diseas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73bdf72cd91992fe6eda01935ca2a29a
https://doi.org/10.1016/s0969-8051(02)00386-4
https://doi.org/10.1016/s0969-8051(02)00386-4
Publikováno v:
Pharmacology & Toxicology. 88:3-15
After the transition from in utero to newborn life, the neonate becomes solely reliant upon its own drug clearance processes to metabolise xenobiotics. Whilst most studies of neonatal hepatic drug elimination have focussed upon in vitro expression an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::380800d48886fe7b85636d20786f91d6
https://doi.org/10.1034/j.1600-0773.2001.088001003.x
https://doi.org/10.1034/j.1600-0773.2001.088001003.x
Publikováno v:
Xenobiotica. 31:757-767
1. The inhibition of recombinant CYP1A1 and CYP1A2 activity by quinidine and quinine was evluated using ethoxyresorutin O-deethylation, phenacetin O-deethylation and propranolol desisopropylation as probe catalytic pathways. 2. With substrate concent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8aebfc528dab867a6244e148cdcff3f5
https://doi.org/10.1080/00498250110065603
https://doi.org/10.1080/00498250110065603
Publikováno v:
Pharmacogenetics. 10:591-603
The tricyclic antidepressant, doxepin, is formulated as an irrational mixture of E (trans) and Z (cis) stereoisomers (85%: 15%). We examined the stereoselective metabolism of doxepin in vitro, with the use of human liver microsomes, recombinant CYP2D
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a77ef1e29b415efff97593b19102a3a0
https://doi.org/10.1097/00008571-200010000-00003
https://doi.org/10.1097/00008571-200010000-00003
Autor:
Denis J. Morgan, Michael S. Ching, Richard A. Smallwood, Arthur Shulkes, Paul J Gow, Saard Treepongkaruna, Hany Ghabrial
Publikováno v:
Journal of Pharmaceutical Sciences. 89:586-593
Using the isolated perfused neonatal sheep liver model, we examined the disposition of propranolol ( n = 8, age 0.25–10 days) and compared our findings with our previous study from the perfused near‐term fetal sheep liver (Ring JA, et al. 1995 .
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60afccf3c19533cb742f2e9f70bb72e0
https://doi.org/10.1002/(sici)1520-6017(200005)89:5<586::aid-jps4>3.0.co
https://doi.org/10.1002/(sici)1520-6017(200005)89:5<586::aid-jps4>3.0.co
Autor:
Michael S. Ching, Arthur Shulkes, Paul J Gow, Denis J. Morgan, Richard A. Smallwood, Hany Ghabrial, Saard Treepongkaruna
Publikováno v:
Journal of Pharmaceutical Sciences. 89:36-44
We examined the metabolism of para‐nitrophenol (PNP) in the isolated perfused neonatal sheep liver ( n = 8, 0.25–11 days) and compared the findings with our previous data from the perfused near‐term fetal sheep liver (Ring, J. A., et al. Drug M
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2903b37ce3fe278c66d251febcdd18a6
https://doi.org/10.1002/(sici)1520-6017(200001)89:1<36::aid-jps4>3.0.co
https://doi.org/10.1002/(sici)1520-6017(200001)89:1<36::aid-jps4>3.0.co
Publikováno v:
Pharmacology & Therapeutics. 84:429-445
The majority of studies of fetal hepatic elimination have concentrated on the expression and activity of the metabolizing enzymes, but the unique physiologic milieu of the fetal liver should also be considered. The basic structure of the liver is for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a87328d05bf35b95041a08fff78b2c2
https://doi.org/10.1016/s0163-7258(99)00046-7
https://doi.org/10.1016/s0163-7258(99)00046-7