Zobrazeno 1 - 10
of 59
pro vyhledávání: '"Michael S. Bereman"'
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-15 (2017)
Author summary TDP-43 aggregation is linked to various diseases including amyotrophic lateral sclerosis. Here the authors show that acetylation of the protein triggers TDP-43 pathology in cultured cells and mouse skeletal muscle, which can be cleared
Externí odkaz:
https://doaj.org/article/46fad8dc2b444576bc81981652f2f6f9
Autor:
Vishal Venkatraman, Anthony J Filiano, Li Xu, Leonard Collins, Emily Luo, Katelyn M Ripple, George C de Castro, Jane-Valeriane K Boua, Choiselle Marius, Charles Giamberardino, Shivanand P Lad, Taufika Islam Williams, Michael S Bereman, Richard S Bedlack
Publikováno v:
Cureus.
Autor:
Michael S. Bereman, Terry Heiman Patterson, Paul Wicks, Paul E. Barkhaus, Kristiana Salmon, Richard Bedlack, James B. Caress, Sky Kihuwa-mani, Gregory T. Carter, Gary L. Pattee, Neta Zach, Jesse Crayle
Publikováno v:
Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration. 22:595-598
Here we use the ALSUntangled methodology to review Tamoxifen as an ALS treatment. We show that it has plausible mechanisms, a positive preclinical study, a case report and 2 small trials suggesting benefits. We show that it appears reasonably safe, t
Exposure to cyanotoxins has been linked to neurodegenerative diseases, including amyotrophic lateral sclerosis, Alzheimer’s, and Parkinson’s disease. While the cyanotoxin β-methylamino-L-alanine (BMAA) has received much attention, cyanobacteria
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::28f33a904a797487e81b192012eef9fc
https://doi.org/10.1101/2021.10.13.464292
https://doi.org/10.1101/2021.10.13.464292
Publikováno v:
Neurotoxicity research. 40(2)
Exposure to cyanotoxins has been linked to neurodegenerative diseases, including amyotrophic lateral sclerosis, Alzheimer’s, and Parkinson’s disease. While the cyanotoxin β-methylamino-L-alanine (BMAA) has received much attention, cyanobacteria
Autor:
Jesse Crayle, Paul Wicks, Paul E. Barkhaus, Pamela Kittrell, Sky Kihuwa-mani, Tulio Bertorini, Gregory T. Carter, Michael S. Bereman, Christopher J McDermott, Robert Bowser, Kristiana Salmon, Richard Bedlack, Gary L. Pattee, Ben Barnes
Publikováno v:
Amyotrophic lateral sclerosisfrontotemporal degeneration. 23(3-4)
ALSUntangled reviews alternative and off-label treatments for people with ALS. Here we review light therapy. We show that it has theoretically plausible mechanisms, three flawed pre-clinical data, studies, and one incompletely documented case report
Publikováno v:
Toxicology. 421:74-83
The goal of this study was to implement powerful mixture design techniques, commonly used in process optimization, to investigate enhanced adverse effects upon co-exposure to environmental cyanotoxins. Exposure to cyanobacteria, which are found ubiqu
Autor:
Anthony M Belenchia, Edward D. Levin, Megan Knuth, Catherine A Peterson, Debrata Mahapatra, Folami Y. Ideraabdullah, Cheryl S. Rosenfeld, Michael S. Bereman, Seth W. Kullman
Publikováno v:
J Endocrinol
Vitamin D is an essential nutrient that is metabolized in the body to generate an active metabolite (1,25(OH)2D) with hormone-like activity and highly diverse roles in cellular function. Vitamin D deficiency (VDD) is a prevalent but easily preventabl
Autor:
Barbara Rothen-Rutishauser, Alke Petri-Fink, Gina M. Hilton, Michael S. Bereman, Hana Barosova
Publikováno v:
Toxicology in Vitro. 54:58-66
With the emerging concern over the potential toxicity associated with carbon nanotube inhalation exposure, several in vitro methods have been developed to evaluate cellular responses. Since the major concern for adverse effects by carbon nanotubes is
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-14 (2018)
Scientific Reports
Scientific Reports
We use shotgun proteomics to identify biomarkers of diagnostic and prognostic value in individuals diagnosed with amyotrophic lateral sclerosis. Matched cerebrospinal and plasma fluids were subjected to abundant protein depletion and analyzed by nano