Zobrazeno 1 - 10
of 195
pro vyhledávání: '"Michael S. Beattie"'
Autor:
Jonathan Z. Pan, Zhanqiang Wang, Wei Sun, Peipei Pan, Wei Li, Yongtao Sun, Shoulin Chen, Amity Lin, Wulin Tan, Liangliang He, Jacob Greene, Virginia Yao, Lijun An, Rich Liang, Qifeng Li, Jessica Yu, Lingyi Zhang, Nikolaos Kyritsis, Xuan Duong Fernandez, Sara Moncivais, Esmeralda Mendoza, Pamela Fung, Gongming Wang, Xinhuan Niu, Qihang Du, Zhaoyang Xiao, Yuwen Chang, Peiyuan Lv, J. Russell Huie, Abel Torres‐Espin, Adam R. Ferguson, Debra D. Hemmerle, Jason F. Talbott, Philip R. Weinstein, Lisa U. Pascual, Vineeta Singh, Anthony M. DiGiorgio, Rajiv Saigal, William D. Whetstone, Geoffrey T. Manley, Sanjay S. Dhall, Jacqueline C. Bresnahan, Mervyn Maze, Xiangning Jiang, Neel S. Singhal, Michael S. Beattie, Hua Su, Zhonghui Guan
Publikováno v:
Clinical and Translational Medicine, Vol 14, Iss 4, Pp n/a-n/a (2024)
Abstract Background Although many molecules have been investigated as biomarkers for spinal cord injury (SCI) or ischemic stroke, none of them are specifically induced in central nervous system (CNS) neurons following injuries with low baseline expre
Externí odkaz:
https://doaj.org/article/05f71d729fcf4e4b9ab7f2a840ded879
Autor:
Gregory Wai, Sharon Zdunowski, Hui Zhong, Jessica L. Nielson, Adam R. Ferguson, Sarah C. Strand, Rod Moseanko, Stephanie Hawbecker, Yvette S. Nout-Lomas, Ephron S. Rosenzweig, Michael S. Beattie, Jacqueline C. Bresnahan, Mark H. Tuszynski, Roland R. Roy, V. Reggie Edgerton
Publikováno v:
Frontiers in Rehabilitation Sciences, Vol 4 (2023)
IntroductionThe paralysis that occurs after a spinal cord injury, particularly during the early stages of post-lesion recovery (∼6 weeks), appears to be attributable to the inability to activate motor pools well beyond their motor threshold. In the
Externí odkaz:
https://doaj.org/article/bd57e01249ac4b0fa4de717ca8f545f1
Autor:
Numaira Obaid, Kazuhito Morioka, Eleni Sinopoulou, Yvette S. Nout-Lomas, Ernesto Salegio, Jacqueline C. Bresnahan, Michael S. Beattie, Carolyn J. Sparrey
Publikováno v:
Frontiers in Neurology, Vol 14 (2023)
Large animal contusion models of spinal cord injury are an essential precursor to developing and evaluating treatment options for human spinal cord injury. Reducing variability in these experiments has been a recent focus as it increases the sensitiv
Externí odkaz:
https://doaj.org/article/afcd16c552a1459d80d3b80e17d4ac12
Autor:
Austin Chou, Abel Torres-Esp?n, J. Russell Huie, Karen Krukowski, Sangmi Lee, Amber Nolan, Caroline Guglielmetti, Bridget E. Hawkins, Myriam M. Chaumeil, Geoffrey T. Manley, Michael S. Beattie, Jacqueline C. Bresnahan, Maryann E. Martone, Jeffrey S. Grethe, Susanna Rosi, Adam R. Ferguson
Publikováno v:
Neurotrauma Reports, Vol 3, Iss 1, Pp 139-157 (2022)
Traumatic brain injury (TBI) is a major public health problem. Despite considerable research deciphering injury pathophysiology, precision therapies remain elusive. Here, we present large-scale data sharing and machine intelligence approaches to leve
Externí odkaz:
https://doaj.org/article/9bc6991af42248f4a5e5593c83ddfc1f
Publikováno v:
Neural Plasticity, Vol 2016 (2016)
Externí odkaz:
https://doaj.org/article/dfe56c669e8c4f1ea4da8528966270d9
Publikováno v:
Neurobiology of Disease, Vol 8, Iss 4, Pp 590-599 (2001)
Excitotoxic cell death due to glutamate release is important in the secondary injury following CNS trauma or ischemia. Proinflammatory cytokines also play a role. Both glutamate and tumor necrosis factor-α (TNFα) are released immediately after spin
Externí odkaz:
https://doaj.org/article/bc1e214d70b44851ab3696f39eaa317a
Autor:
Ellen D. Stück, Randolph N. Christensen, J. Russell Huie, C. Amy Tovar, Brandon A. Miller, Yvette S. Nout, Jacqueline C. Bresnahan, Michael S. Beattie, Adam R. Ferguson
Publikováno v:
Neural Plasticity, Vol 2012 (2012)
The proinflammatory cytokine TNFα contributes to cell death in central nervous system (CNS) disorders by altering synaptic neurotransmission. TNFα contributes to excitotoxicity by increasing GluA2-lacking AMPA receptor (AMPAR) trafficking to the ne
Externí odkaz:
https://doaj.org/article/89292cf6a78a4e80929822a2116e10ed
Autor:
Austin Chou, Abel Torres-Espin, Nikos Kyritsis, J Russell Huie, Sarah Khatry, Jeremy Funk, Jennifer Hay, Andrew Lofgreen, Rajiv Shah, Chandler McCann, Lisa U Pascual, Edilberto Amorim, Philip R Weinstein, Geoffrey T Manley, Sanjay S Dhall, Jonathan Z Pan, Jacqueline C Bresnahan, Michael S Beattie, William D Whetstone, Adam R Ferguson, TRACK-SCI Investigators
Publikováno v:
PLoS ONE, Vol 17, Iss 4, p e0265254 (2022)
Artificial intelligence and machine learning (AI/ML) is becoming increasingly more accessible to biomedical researchers with significant potential to transform biomedicine through optimization of highly-accurate predictive models and enabling better
Externí odkaz:
https://doaj.org/article/bec17b8aaf234782a7d80a492d9dbb4e
Autor:
Abel Torres-Espín, Jenny Haefeli, Reza Ehsanian, Dolores Torres, Carlos A Almeida, J Russell Huie, Austin Chou, Dmitriy Morozov, Nicole Sanderson, Benjamin Dirlikov, Catherine G Suen, Jessica L Nielson, Nikos Kyritsis, Debra D Hemmerle, Jason F Talbott, Geoffrey T Manley, Sanjay S Dhall, William D Whetstone, Jacqueline C Bresnahan, Michael S Beattie, Stephen L McKenna, Jonathan Z Pan, Adam R Ferguson, The TRACK-SCI Investigators
Publikováno v:
eLife, Vol 10 (2021)
Background: Predicting neurological recovery after spinal cord injury (SCI) is challenging. Using topological data analysis, we have previously shown that mean arterial pressure (MAP) during SCI surgery predicts long-term functional recovery in roden
Externí odkaz:
https://doaj.org/article/deaeee6d6a7c4743a5ba3373d4ca53da
Autor:
Nitin Agarwal, Jacob Blitstein, Austin Lui, Abel Torres-Espin, Chalisar Vasnarungruengkul, John Burke, Praveen V. Mummaneni, Sanjay S. Dhall, Philip R. Weinstein, Xuan Duong-Fernandez, Austin Chou, Jonathan Pan, Vineeta Singh, Adam R. Ferguson, Debra D. Hemmerle, Nikos Kyritsis, Jason F. Talbott, William D. Whetstone, Jacqueline C. Bresnahan, Michael S. Beattie, Geoffrey T. Manley, Anthony DiGiorgio
Publikováno v:
Journal of Neurosurgery: Spine. :1-9
OBJECTIVE Increasing life expectancy has led to an older population. In this study, the authors analyzed complications and outcomes in elderly patients following spinal cord injury (SCI) using the established multi-institutional prospective study Tra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::76b74b58c15224fd493e97dd5c7b2cef
https://doi.org/10.3171/2023.2.spine221043
https://doi.org/10.3171/2023.2.spine221043