Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Michael S. Balzer"'
Autor:
Toshiharu Onodera, May-Yun Wang, Joseph M. Rutkowski, Stanislaw Deja, Shiuhwei Chen, Michael S. Balzer, Dae-Seok Kim, Xuenan Sun, Yu A. An, Bianca C. Field, Charlotte Lee, Ei-ichi Matsuo, Monika Mizerska, Ina Sanjana, Naoto Fujiwara, Christine M. Kusminski, Ruth Gordillo, Laurent Gautron, Denise K. Marciano, Ming Chang Hu, Shawn C. Burgess, Katalin Susztak, Orson W. Moe, Philipp E. Scherer
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-20 (2023)
Abstract Adiponectin is a secretory protein, primarily produced in adipocytes. However, low but detectable expression of adiponectin can be observed in cell types beyond adipocytes, particularly in kidney tubular cells, but its local renal role is un
Externí odkaz:
https://doaj.org/article/6885cd75dd3641e481d840972315e815
Autor:
Michael S. Balzer, Tomohito Doke, Ya-Wen Yang, Daniel L. Aldridge, Hailong Hu, Hung Mai, Dhanunjay Mukhi, Ziyuan Ma, Rojesh Shrestha, Matthew B. Palmer, Christopher A. Hunter, Katalin Susztak
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)
After acute injury, kidneys either successfully repair/regenerate or become fibrotic. Here the authors use scRNA-seq to study adaptive/maladaptive kidney regeneration and identify proinflammatory/fibrotic proximal tubule cells with pharmacologically
Externí odkaz:
https://doaj.org/article/46df2867ad71422c9efdf5a76af48418
Autor:
Zhen Miao, Michael S. Balzer, Ziyuan Ma, Hongbo Liu, Junnan Wu, Rojesh Shrestha, Tamas Aranyi, Amy Kwan, Ayano Kondo, Marco Pontoglio, Junhyong Kim, Mingyao Li, Klaus H. Kaestner, Katalin Susztak
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
Epigenetic and transcriptional dynamics are critical for both tissue homeostasis and injury response in the kidney. Leveraging a single cell multiomics atlas of the developing mouse kidney, the authors reveal key events in chromatin regulation and ge
Externí odkaz:
https://doaj.org/article/041359208fd74d1f952a6f800451b64e
Autor:
Laura Kutzner, Katharina M. Rund, Annika I. Ostermann, Nicole M. Hartung, Jean-Marie Galano, Laurence Balas, Thierry Durand, Michael S. Balzer, Sascha David, Nils Helge Schebb
Publikováno v:
Frontiers in Pharmacology, Vol 10 (2019)
The cardioprotective and anti-inflammatory effects of long chain omega-3 polyunsaturated fatty acids (n3 PUFA) are believed to be partly mediated by their oxygenated metabolites (oxylipins). In the last two decades interest in a novel group of autaco
Externí odkaz:
https://doaj.org/article/346ccb628f7844e190b88ce537035040
Autor:
Michael S. Balzer, Song Rong, Johannes Nordlohne, Jan D. Zemtsovski, Sonja Schmidt, Britta Stapel, Maria Bartosova, Sibylle von Vietinghoff, Hermann Haller, Claus P. Schmitt, Nelli Shushakova
Publikováno v:
Biomolecules, Vol 10, Iss 11, p 1573 (2020)
Peritoneal dialysis (PD) is limited by glucose-mediated peritoneal membrane (PM) fibrosis, angiogenesis, and ultrafiltration failure. Influencing PM integrity by pharmacologically targeting sodium-dependent glucose transporter (SGLT)-mediated glucose
Externí odkaz:
https://doaj.org/article/811cdbee73794be98d18beecedd5bfe6
Publikováno v:
Annu Rev Physiol
The kidney maintains electrolyte, water, and acid-base balance, eliminates foreign and waste compounds, regulates blood pressure, and secretes hormones. There are at least 16 different highly specialized epithelial cell types in the mammalian kidney.
Autor:
Amin Abedini, Ziyuan Ma, Julia Frederick, Poonam Dhillon, Michael S. Balzer, Rojesh Shrestha, Hongbo Liu, Steven Vitale, Kishor Devalaraja-Narashimha, Paola Grandi, Tanmoy Bhattacharyya, Erding Hu, Steven S. Pullen, Carine M Boustany-Kari, Paolo Guarnieri, Anil Karihaloo, Hanying Yan, Kyle Coleman, Matthew Palmer, Lea Sarov-Blat, Lori Morton, Christopher A. Hunter, Mingyao Li, Katalin Susztak
Kidneys have one of the most complex three-dimensional cellular organizations in the body, but the spatial molecular principles of kidney health and disease are poorly understood. Here we generate high-quality single cell (sc), single nuclear (sn), s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5ef1d19933dc237011cb55146afd17db
https://doi.org/10.1101/2022.10.24.513598
https://doi.org/10.1101/2022.10.24.513598
Autor:
Michael S. Balzer, Mira Pavkovic, Julia Frederick, Amin Abedini, Alexius Freyberger, Julia Vienenkötter, Ilka Mathar, Krystyna Siudak, Frank Eitner, Peter Sandner, Manuel Grundmann, Katalin Susztak
Publikováno v:
Cell Reports Medicine. 4:100992
Autor:
Amin, Abedini, Yuan O, Zhu, Shatakshee, Chatterjee, Gabor, Halasz, Kishor, Devalaraja-Narashimha, Rojesh, Shrestha, Michael S, Balzer, Jihwan, Park, Tong, Zhou, Ziyuan, Ma, Katie Marie, Sullivan, Hailong, Hu, Xin, Sheng, Hongbo, Liu, Yi, Wei, Carine M, Boustany-Kari, Uptal, Patel, Salem, Almaani, Matthew, Palmer, Raymond, Townsend, Shira, Blady, Jonathan, Hogan, Lori, Morton, Katalin, Susztak, Yan, Zhong
Publikováno v:
J Am Soc Nephrol
Background Microscopic analysis of urine sediment is probably the most commonly used diagnostic procedure in nephrology. The urinary cells, however, have not yet undergone careful unbiased characterization. Methods Single-cell transcriptomic analysis
Autor:
Dominik Berliner, Johann Bauersachs, Udo Bavendiek, Hermann Haller, Robert Claus, Michael S. Balzer, Marcus Hiss, Ralf Lichtinghagen, Jean-Marie Launay, Nicolas Vodovar, Sascha David, Margret Patecki
Publikováno v:
Clinical Research in Cardiology
Background Dialysis patients are at increased risk of HF. However, diagnostic utility of NT-proBNP as a biomarker is decreased in patients on dialysis. GDF-15 and cNEP are biomarkers of distinct mechanisms that may contribute to HF pathophysiology in