Zobrazeno 1 - 10
of 109
pro vyhledávání: '"Michael S. Aldrich"'
Autor:
Michael S. Aldrich
This book offers a concise, methodological approach to the evaluation and treatment of patients with sleep disorders. The management of sleep disorders requires an understanding of sleep itself, thus the book initially discusses aspects of normal sle
Autor:
Sebastiaan Overeem, Michael S. Aldrich, Muralidhara Padigaru, Robin Li, Christelle Peyron, Yves Charnay, Constantin Bouras, Roger L. Albin, Seiji Nishino, Mario Pedrazzoli, Emmanuel Mignot, Raju Kucherlapati, Juliette Faraco, David Reynolds, Beth Ripley, William J. Rogers, Marcel Hungs, Gert Jan Lammers, Sona Nevsimalova, Jun Fan, Richard A. Maki, Melanie H. Kucherlapati
Publikováno v:
ResearcherID
We explored the role of hypocretins in human narcolepsy through histopathology of six narcolepsy brains and mutation screening of Hcrt, Hcrtr1 and Hcrtr2 in 74 patients of various human leukocyte antigen and family history status. One Hcrt mutation,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41c121df81339ffe1380cedf8a508465
https://doi.org/10.1038/79690
https://doi.org/10.1038/79690
Autor:
Lalini Ramanathan, Thomas C. Thannickal, Seema Gulyani, Michael S. Aldrich, Jerome M. Siegel, Robert Y. Moore, Robert Nienhuis, Marsha Cornford
Publikováno v:
Neuron
Murine and canine narcolepsy can be caused by mutations of the hypocretin (Hcrt) (orexin) precursor or Hcrt receptor genes. In contrast to these animal models, most human narcolepsy is not familial, is discordant in identical twins, and has not been
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::557ae87c1f95077111967d3bd610902b
Publikováno v:
Epilepsia. 40:1587-1592
Summary: Purpose: To determine the lateralizing value of interictal epileptiform discharges (IEDs) recorded during overnight sleep-EEG studies in temporal lobe epilepsy. Because IEDs are more prevalent in non-rapid eye movement (NREM) sleep than in w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::506bf5f92099bcf021d0eafda0f6ba7e
https://doi.org/10.1111/j.1528-1157.1999.tb02044.x
https://doi.org/10.1111/j.1528-1157.1999.tb02044.x
Publikováno v:
Alcoholism: Clinical and Experimental Research. 23:134-140
Sleep apnea and related disorders contribute to disturbed sleep in abstinent alcoholics. In an earlier report from our group, sleep-disordered breathing was common and increased with age in a cohort of 75 abstinent alcoholics. We now report an extens
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::737225a41c4b771a5c8ffd564e19411d
https://doi.org/10.1111/j.1530-0277.1999.tb04034.x
https://doi.org/10.1111/j.1530-0277.1999.tb04034.x
Publikováno v:
Alcoholism: Clinical and Experimental Research. 22:1864-1871
Previous studies indicate that subjectively reported and objectively measured sleep abnormalities at baseline can increase the risk of relapse in treated alcoholics. However, previous studies did not include both subjective and objective sleep measur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3e71644ec42efb5788c386601d3e7313
https://doi.org/10.1111/j.1530-0277.1998.tb03995.x
https://doi.org/10.1111/j.1530-0277.1998.tb03995.x
Autor:
Ronald D. Chervin, Michael S. Aldrich
Publikováno v:
Chest. 113:980-984
A recent study of 34 patients with mild obstructive sleep apnea syndrome (OSAS) suggested that the number of apneas and hypopneas per hour of sleep (apnea/hypopnea index [AHI]) may show a stronger correlation with sleepiness, as measured by the Multi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09966e8fd71bdc45237ce5b00e2641fe
https://doi.org/10.1378/chest.113.4.980
https://doi.org/10.1378/chest.113.4.980
Publikováno v:
Stroke. 28:1765-1772
Background and Purpose Although recent studies suggest a high prevalence of obstructive sleep apnea (OSA) in patients with acute stroke, a systematic characterization of sleep-disordered breathing based on the severity and topography of stroke has no
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3bc5fffabd5dee9419370bb7a69b58cf
https://doi.org/10.1161/01.str.28.9.1765
https://doi.org/10.1161/01.str.28.9.1765
Autor:
Michael S. Aldrich, Michael C. Ellis, Dennis Drayna, Erin E. McClelland, Emmanuel Mignot, Leah Quintana, Angela H. Hetisimer, David A. Ruddy, Gregory S. Kronmal, Sherry L. Hansen
Publikováno v:
Immunogenetics. 46:410-417
A systematic haplotype and sequencing analysis of the HLA-DR and -DQ region in patients with narcolepsy was performed. Five new (CA)n microsatellite markers were generated and positioned on the physical map across the HLA-DQB1-DQA1-DRB1 interval. Hap
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0598de47e4d1837df08f948e63c1e91
https://doi.org/10.1007/s002510050295
https://doi.org/10.1007/s002510050295
Publikováno v:
Neurology. 48:1389-1394
We reviewed the records of 63 adult epilepsy patients who underwent polysomnograms in our laboratory since 1985 to determine the indications for polysomnography and the results of testing. Reasons for referral included excessive daytime sleepiness, s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c901bd5a210ac04e606c18ccb7948f48
https://doi.org/10.1212/wnl.48.5.1389
https://doi.org/10.1212/wnl.48.5.1389