Zobrazeno 1 - 10
of 112
pro vyhledávání: '"Michael S Parmacek"'
Autor:
Yongfeng Luo, Ke Cao, Joanne Chiu, Hui Chen, Hong-Jun Wang, Matthew E Thornton, Brendan H Grubbs, Martin Kolb, Michael S Parmacek, Yuji Mishina, Wei Shi
Publikováno v:
eLife, Vol 12 (2024)
Abnormal lung development can cause congenital pulmonary cysts, the mechanisms of which remain largely unknown. Although the cystic lesions are believed to result directly from disrupted airway epithelial cell growth, the extent to which developmenta
Externí odkaz:
https://doaj.org/article/310cc91eef7547f0b2c6ff8d0cb9222f
Autor:
Qin Yang, Qing Miao, Hui Chen, Duo Li, Yongfeng Luo, Joanne Chiu, Hong‐Jun Wang, Michael Chuvanjyan, Michael S Parmacek, Wei Shi
Publikováno v:
The Journal of Pathology. 259:331-341
Abnormal growth of airway smooth muscle cells is one of the key features in asthmatic airway remodeling, which is associated with asthma severity. The mechanisms underlying inappropriate airway smooth muscle cell growth in asthma remain largely unkno
Autor:
Mary Norine Walsh, James A. Arrighi, Joseph G. Cacchione, Anna Lisa Chamis, Pamela S. Douglas, Claire S. Duvernoy, JoAnne M. Foody, Sharonne N. Hayes, Dipti Itchhaporia, Michael S. Parmacek, Ada C. Stefanescu Schmidt, George W. Vetrovec, Thad F. Waites, John J. Warner
Publikováno v:
Journal of the American College of Cardiology. 80:2135-2155
Autor:
Daniel J. Rader, Michael S. Parmacek, Pengxiang Li, Justin T. Puckett, Amy R. Pettit, Swathi Raman, Jalpa A. Doshi
Publikováno v:
Value in Health. 23:209-216
Objectives Proprotein convertase subtilisin/kexin type 9 inhibitors (PCSK9is)—innovative yet costly cholesterol-lowering agents—have been subject to substantial prior authorization (PA) requirements and low approval rates. We aimed to investigate
Autor:
John M. Carethers, Mark W. Geraci, Mark E. Anderson, Anthony N. Hollenberg, David L. Coleman, Anne B. Curtis, Richard J. Robbins, Mark T. Gladwin, Alpesh Amin, Patricia W. Finn, E. Dale Abel, Michael S. Parmacek
Publikováno v:
The American journal of medicine. 134(7)
Autor:
Jalpa A. Doshi, Justin T. Puckett, Pengxiang Li, Michael S. Parmacek, Daniel J. Rader, Amy R. Pettit
Publikováno v:
Circulation: Cardiovascular Quality and Outcomes. 13
Background: Specialty drugs are typically subject to high out-of-pocket (OOP) costs, especially for Medicare Part D patients and commercially insured patients facing high deductibles and/or coinsurance. Financial assistance offered by charities or ma
Autor:
Neal G. Copeland, Jian Li, Takahiro Kodama, Michael S. Parmacek, Michiko Kodama, Teresa A. Marian, Zhubo Wei, Hubert Lee, Nancy A. Jenkins
Publikováno v:
Proc Natl Acad Sci U S A
Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America
Myocardin-related transcription factor B (MRTFB) is a candidate tumor-suppressor gene identified in transposon mutagenesis screens of the intestine, liver, and pancreas. Using a combination of cell-based assays, in vivo tumor xenograft assays, and Mr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80cc34572e8b40b4831e4bfca8b714ad
https://europepmc.org/articles/PMC6876235/
https://europepmc.org/articles/PMC6876235/
Autor:
Wajihah Mughal, Matthew Martens, Donald Chapman, Yan Hai, Joseph W. Gordon, Vernon W. Dolinsky, Adrian R. West, Laura K. Cole, Kyle G. Cheung, William Diehl-Jones, Jared T. Field, Ian M.C. Dixon, Sunil G. Rattan, Richard Keijzer, Stephanie M. Kereliuk, Michael S. Parmacek, Jianhe Huang, Grant M. Hatch
Publikováno v:
Cell Death and Differentiation
Myocardin is a transcriptional co-activator required for cardiovascular development, but also promotes cardiomyocyte survival through an unclear molecular mechanism. Mitochondrial permeability transition is implicated in necrosis, while pore closure
Autor:
X. Long Zheng, Jian Cui, Daniel J. Rader, Muredach P. Reilly, Xuan Zhang, Kristy Ou, Jifu Yang, Junichiro Tohyama, Georgios K. Paschos, Lan Cheng, Robert C. Bauer, Michael S. Parmacek
Publikováno v:
Circulation. 131:1202-1213
Background— Genome-wide association studies have established ADAMTS7 as a locus for coronary artery disease in humans. However, these studies fail to provide directionality for the association between ADAMTS7 and coronary artery disease. Previous r
Publikováno v:
Circulation. Cardiovascular quality and outcomes. 11(1)
Background: Proprotein convertase subtilisin/kexin type 9 inhibitors (PCSK9is) are an innovative treatment option for patients with familial hypercholesterolemia or clinical atherosclerotic cardiovascular disease who require further lowering of low-d