Zobrazeno 1 - 10
of 300
pro vyhledávání: '"Michael S Fanselow"'
Autor:
Garrett J Blair, Changliang Guo, Shiyun Wang, Michael S Fanselow, Peyman Golshani, Daniel Aharoni, Hugh T Blair
Publikováno v:
eLife, Vol 12 (2023)
Aversive stimuli can cause hippocampal place cells to remap their firing fields, but it is not known whether remapping plays a role in storing memories of aversive experiences. Here, we addressed this question by performing in vivo calcium imaging of
Externí odkaz:
https://doaj.org/article/dc1cf19e39d1456eac6e39ac462b6e84
Publikováno v:
eLife, Vol 11 (2022)
Fear conditioning is one of the most frequently used laboratory procedures for modeling learning and memory generally, and anxiety disorders in particular. The conditional response (CR) used in the majority of fear conditioning studies in rodents is
Externí odkaz:
https://doaj.org/article/8f7f6204c9f349cd96cd0b50cb9518c0
Publikováno v:
PLoS ONE, Vol 17, Iss 9, p e0273803 (2022)
Exposure to traumatic stress leads to persistent, deleterious behavioral and biological changes in both human and non-human species. The effects of stress are not always consistent, however, as exposure to different stressors often leads to heterogen
Externí odkaz:
https://doaj.org/article/0ab4ca75b32e43a9b3f5831957bb657f
Autor:
Michael A. Conoscenti, Daniel B. Weatherill, Yuqing Huang, Raphael Tordjman, Michael S. Fanselow
Publikováno v:
Neurobiology of Stress, Vol 30, Iss , Pp 100616- (2024)
Firm conclusions regarding the differential effects of the maladaptive consequences of acute versus chronic stress on the etiology and symptomatology of stress disorders await a model that isolates chronicity as a variable for studying the differenti
Externí odkaz:
https://doaj.org/article/06e9bf51f921487e9ab892cfa798188a
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 6 (2012)
Anxiety disorders are often treated using extinction-based exposure therapy, but relapse is common and can occur as a result of reinstatement, whereby an aversive trigger can reinstate extinguished fear. Animal models of reinstatement commonly utiliz
Externí odkaz:
https://doaj.org/article/d968135afd9d4014b2025e6338123f4e
Autor:
Jesse Daniel Cushman, Jose eMaldonado, Eunice E Kwon, Denise A Garcia, Guoping eFan, Tetsuya eImura, Michael V Sofroniew, Michael S Fanselow
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 6 (2012)
Postnatal-neurogenesis (PNN) contributes neurons to olfactory bulb (OB) and dentate gyrus (DG) throughout juvenile development, but the quantitative amount, temporal dynamics and functional roles of this contribution have not been defined. By using t
Externí odkaz:
https://doaj.org/article/bc34bed0e54c49ecb2b6ec3a60ca11cd
Autor:
Brian J Wiltgen, Gordon A Royle, Erin E Gray, Andrea Abdipranoto, Nopporn Thangthaeng, Nate Jacobs, Faysal Saab, Susumu Tonegawa, Stephen F Heinemann, Thomas J O'Dell, Michael S Fanselow, Bryce Vissel
Publikováno v:
PLoS ONE, Vol 5, Iss 9 (2010)
A central concept in the field of learning and memory is that NMDARs are essential for synaptic plasticity and memory formation. Surprisingly then, multiple studies have found that behavioral experience can reduce or eliminate the contribution of the
Externí odkaz:
https://doaj.org/article/070d953a46ae4bb5a7187a01a6fc26ce
Autor:
Anna Matynia, Stephan G Anagnostaras, Brian J Wiltgen, Maress Lacuesta, Michael S Fanselow, Alcino J Silva
Publikováno v:
PLoS ONE, Vol 3, Iss 5, p e2121 (2008)
Previous studies have revealed that the initial stages of memory formation require several genes involved in synaptic, transcriptional and translational mechanisms. In contrast, very little is known about the molecular and cellular mechanisms underly
Externí odkaz:
https://doaj.org/article/df9b05bbc5864773a31d5f03cb44cc81
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 17 (2024)
Here, we propose a model of remote memory (BaconREM), which is an extension of a previously published Bayesian model of context fear learning (BACON) that accounts for many aspects of recently learned context fear. BaconREM simulates most known pheno
Externí odkaz:
https://doaj.org/article/b818050aeecc440ca8fab34da64dded8
Publikováno v:
Neurotrauma Reports, Vol 2, Iss 1, Pp 200-213 (2021)
Traumatic brain injury (TBI)-induced disruptions in synaptic function within brain regions and across networks in the limbic system may underlie a vulnerability for maladaptive plasticity and contribute to behavioral comorbidities. In this study we m
Externí odkaz:
https://doaj.org/article/83dedb4ffce846c5a188e6c46881d53f