Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Michael S Burhans"'
Autor:
Michael S Burhans, Lisa A Martin, Burns C. Blaxall, Jason M Mulvaney, Yaejee H Hong, Robert B Hinton
Publikováno v:
Biopreservation and Biobanking. 13:123-130
Isolation of high-quality RNA from tissue is mandatory for producing reliable data for downstream applications. In heart tissue, the relative strengths and weaknesses of different approaches to isolate total RNA are unknown. The objective of this stu
Autor:
Xiaofei Shangguan, Michael S. Burhans, John M. Shannon, Kathleen McCormick-Shannon, Brian A. Hyatt, Kalpana Srivastava
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology. 285:L1323-L1336
Proteoglycans (PGs) have been shown to play a key role in the development of many tissues. We have investigated the role of sulfated PGs in early rat lung development by treating cultured tissues with 30 mM sodium chlorate, a global inhibitor of PG s
Autor:
Emily M Schulz, Allison E Dixon, Michael S Burhans, Michelle L Nieman, John N Lorenz, Val Goodfellow, Harris A Gelbard, Stephen Dewhurst, Burns C Blaxall
Publikováno v:
Circulation Research. 115
Mixed lineage kinase 3 (MLK3) is a ubiquitously expressed pro-inflammatory, pro-apoptotic mitogen activated protein kinase kinase kinase (MAP3K). MLK3 is a key regulator of the p38 and c-jun terminal kinase (JNK) pathways and has been studied in canc
Publikováno v:
Circulation Research. 115
Heart failure (HF) is a devastating disease characterized by chamber remodeling, interstitial fibrosis and reduced ventricular compliance. Prolonged sympathetic overstimulation promotes excess signaling through G-protein Gβγ subunits and ultimately
Autor:
Cheng-Lun Na, Stephan W. Glasser, Peter D. Sly, Machiko Ikegami, Thomas R. Korfhagen, Michael S. Burhans, Jeffrey A. Whitsett, Gary F. Ross
Publikováno v:
Proceedings of the National Academy of Sciences. 98:6366-6371
The surfactant protein C (SP-C) gene encodes an extremely hydrophobic, 4-kDa peptide produced by alveolar epithelial cells in the lung. To discern the role of SP-C in lung function, SP-C-deficient (−/−) mice were produced. The SP-C (−/−) mice
Autor:
Gary F. Ross, Mildred T. Stahlman, Michael S. Burhans, Michael D. Bruno, James H. Fisher, Susan E. Wert, Jeffrey A. Whitsett, Machiko Ikegami, Alan H. Jobe, Vladimir Sheftelyevich, Thomas R. Korfhagen
Publikováno v:
Journal of Biological Chemistry. 273:28438-28443
Surfactant protein D (SP-D) is a 43-kDa member of the collectin family of collagenous lectin domain-containing proteins that is expressed in epithelial cells of the lung. The SP-D gene was targeted by homologous recombination in embryonic stem cells
Publikováno v:
Journal of Biological Chemistry. 271:6881-6888
Surfactant protein C (SP-C) is expressed in alveolar Type II epithelial cells of the lung. In order to determine the mechanism(s) that regulate gene transcription, we have analyzed the activation of the murine SP-C promoter in mouse lung epithelial c
Publikováno v:
A54. PRENATAL AND POSTNATAL LUNG DEVELOPMENT.
Autor:
Vladimir V. Kalinichenko, Michael S. Burhans, Mardi J. Sutherland, Jonathan Snyder, Jeffrey A. Whitsett, Hyun Jung Park, Yufang Zhang, John M. Shannon, I-Ching Wang
Publikováno v:
Developmental biology. 347(2)
Foxm1 is a member of the Forkhead Box (Fox) family of transcription factors. Foxm1 (previously called Foxm1b, HFH-11B, Trident, Win, or MPP2) is expressed in multiple cell types and plays important roles in cellular proliferation, differentiation and
Autor:
Theresa R. Richardson, Thomas R. Korfhagen, James H. Fisher, Jodie Gwozdz, Michael S. Burhans, Ann Marie LeVine, Jeffrey A. Whitsett
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 165(7)
Mice lacking surfactant protein (SP)-A (SP-A−/−) or SP-D (SP-D−/−) and wild-type mice were infected with group B streptococcus or Haemophilus influenzae by intratracheal instillation. Although decreased killing of group B streptococcus and H.