Zobrazeno 1 - 10
of 937
pro vyhledávání: '"Michael S, Okun"'
Autor:
Chang Su, Yu Hou, Jielin Xu, Zhenxing Xu, Manqi Zhou, Alison Ke, Haoyang Li, Jie Xu, Matthew Brendel, Jacqueline R. M. A. Maasch, Zilong Bai, Haotan Zhang, Yingying Zhu, Molly C. Cincotta, Xinghua Shi, Claire Henchcliffe, James B. Leverenz, Jeffrey Cummings, Michael S. Okun, Jiang Bian, Feixiong Cheng, Fei Wang
Publikováno v:
npj Digital Medicine, Vol 7, Iss 1, Pp 1-22 (2024)
Abstract Parkinson’s disease (PD) is a serious neurodegenerative disorder marked by significant clinical and progression heterogeneity. This study aimed at addressing heterogeneity of PD through integrative analysis of various data modalities. We a
Externí odkaz:
https://doaj.org/article/c98b774780634551a2636756a95523ae
Autor:
Jackson N. Cagle, Tiberio de Araujo, Kara A. Johnson, John Yu, Lauren Fanty, Filipe P. Sarmento, Simon Little, Michael S. Okun, Joshua K. Wong, Coralie de Hemptinne
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-9 (2024)
Abstract Circadian rhythms have been shown in the subthalamic nucleus (STN) in Parkinson’s disease (PD), but only a few studies have focused on the globus pallidus internus (GPi). This retrospective study investigates GPi circadian rhythms in a lar
Externí odkaz:
https://doaj.org/article/39afb35889d1462bb77151b9ba692e06
Autor:
Michael S. Okun, Jackson Cagle, Julieth Gomez, Dawn Bowers, Joshua Wong, Kelly D. Foote, Aysegul Gunduz
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract To report the results of ‘responsive’ deep brain stimulation (DBS) for Tourette syndrome (TS) in a National Institutes of Health funded experimental cohort. The use of ‘brain derived physiology’ as a method to trigger DBS devices to
Externí odkaz:
https://doaj.org/article/a3f5e40819524095931dbc044895ee80
Autor:
Kara A. Johnson, James J. Giordano, Adolfo Ramirez-Zamora, Marta San Luciano, Svjetlana Miocinovic, Michael S. Okun, Joshua K. Wong
Publikováno v:
Frontiers in Human Neuroscience, Vol 18 (2024)
Externí odkaz:
https://doaj.org/article/a3216ce54ba945929ffedc62116665b1
Autor:
Hooman Azmi, Benjamin L. Walter, Annie Brooks, Irene Hegeman Richard, Katherine Amodeo, Michael S. Okun
Publikováno v:
Frontiers in Aging Neuroscience, Vol 16 (2024)
Externí odkaz:
https://doaj.org/article/9031fbc1b34747329bf9a75206c531fe
Autor:
Amanda R. Merner, Kristin Kostick-Quenet, Tiffany A. Campbell, Michelle T. Pham, Clarissa E. Sanchez, Laura Torgerson, Jill Robinson, Stacey Pereira, Simon Outram, Barbara A. Koenig, Philip A. Starr, Aysegul Gunduz, Kelly D. Foote, Michael S. Okun, Wayne Goodman, Amy L. McGuire, Peter Zuk, Gabriel Lázaro-Muñoz
Publikováno v:
Brain Stimulation, Vol 16, Iss 4, Pp 990-998 (2023)
Background: There has been substantial controversy in the neuroethics literature regarding the extent to which deep brain stimulation (DBS) impacts dimensions of personality, mood, and behavior.Objective/Hypothesis: Despite extensive debate in the th
Externí odkaz:
https://doaj.org/article/fa8b698db919458da6f3bfd02e749d14
Autor:
Alfonso Enrique Martinez-Nunez, Filipe P. Sarmento, Vyshak Chandra, Christopher William Hess, Justin David Hilliard, Michael S. Okun, Joshua K. Wong
Publikováno v:
Frontiers in Human Neuroscience, Vol 18 (2024)
Deep brain stimulation (DBS) is an effective surgical therapy for carefully selected patients with medication refractory essential tremor (ET). The most popular anatomical targets for ET DBS are the ventral intermedius nucleus (VIM) of the thalamus,
Externí odkaz:
https://doaj.org/article/c5fba4afe88c4a429047293f8df37af0
Autor:
Kara A. Johnson, Nico U. F. Dosenbach, Evan M. Gordon, Cristin G. Welle, Kevin B. Wilkins, Helen M. Bronte-Stewart, Valerie Voon, Takashi Morishita, Yuki Sakai, Amanda R. Merner, Gabriel Lázaro-Muñoz, Theresa Williamson, Andreas Horn, Ro'ee Gilron, Jonathan O'Keeffe, Aryn H. Gittis, Wolf-Julian Neumann, Simon Little, Nicole R. Provenza, Sameer A. Sheth, Alfonso Fasano, Abbey B. Holt-Becker, Robert S. Raike, Lisa Moore, Yagna J. Pathak, David Greene, Sara Marceglia, Lothar Krinke, Huiling Tan, Hagai Bergman, Monika Pötter-Nerger, Bomin Sun, Laura Y. Cabrera, Cameron C. McIntyre, Noam Harel, Helen S. Mayberg, Andrew D. Krystal, Nader Pouratian, Philip A. Starr, Kelly D. Foote, Michael S. Okun, Joshua K. Wong
Publikováno v:
Frontiers in Human Neuroscience, Vol 18 (2024)
The Deep Brain Stimulation (DBS) Think Tank XI was held on August 9–11, 2023 in Gainesville, Florida with the theme of “Pushing the Forefront of Neuromodulation”. The keynote speaker was Dr. Nico Dosenbach from Washington University in St. Loui
Externí odkaz:
https://doaj.org/article/fc6de2dbe53a4e2f9c89187bbb059f86
Autor:
Bradley J. Wilkes, Emily R. Tobin, David J. Arpin, Wei-en Wang, Michael S. Okun, Michael S. Jaffee, Nikolaus R. McFarland, Daniel M. Corcos, David E. Vaillancourt
Publikováno v:
npj Parkinson's Disease, Vol 9, Iss 1, Pp 1-11 (2023)
Abstract Objective measures of disease progression are critically needed in research on Parkinson’s disease (PD) and atypical Parkinsonism but may be hindered by both practicality and cost. The Purdue Pegboard Test (PPT) is objective, has high test
Externí odkaz:
https://doaj.org/article/7e8bb34fb98742c4bfda1a7e47ddb135
Autor:
Frederick L. Hitti, Alik S. Widge, Patricio Riva-Posse, Donald A. Malone, Jr., Michael S. Okun, Maryam M. Shanechi, Kelly D. Foote, Sarah H. Lisanby, Elizabeth Ankudowich, Srinivas Chivukula, Edward F. Chang, Aysegul Gunduz, Clement Hamani, Ashley Feinsinger, Cynthia S. Kubu, Winston Chiong, Jennifer A. Chandler, Rafael Carbunaru, Binith Cheeran, Robert S. Raike, Rachel A. Davis, Casey H. Halpern, Nora Vanegas-Arroyave, Dejan Markovic, Sarah K. Bick, Cameron C. McIntyre, R. Mark Richardson, Darin D. Dougherty, Brian H. Kopell, Jennifer A. Sweet, Wayne K. Goodman, Sameer A. Sheth, Nader Pouratian
Publikováno v:
Brain Stimulation, Vol 16, Iss 3, Pp 867-878 (2023)
Objective.Despite advances in the treatment of psychiatric diseases, currently available therapies do not provide sufficient and durable relief for as many as 30–40% of patients. Neuromodulation, including deep brain stimulation (DBS), has emerged
Externí odkaz:
https://doaj.org/article/646a194141a143ab836dbfa7678f5e4a