Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Michael S, DeMott"'
Autor:
Taylor Wadley, Sun Hee Moon, Michael S. DeMott, Visanu Wanchai, En Huang, Peter C. Dedon, Gunnar Boysen, Intawat Nookaew
Publikováno v:
Frontiers in Microbiology, Vol 13 (2022)
Bacterial DNA is subject to various modifications involved in gene regulation and defense against bacteriophage attacks. Phosphorothioate (PT) modifications are protective modifications in which the non-bridging oxygen in the DNA phosphate backbone i
Externí odkaz:
https://doaj.org/article/0de20ba09afe4a868070b14e4b343c4a
Autor:
Sucheng Zhu, Tao Zheng, Lingxin Kong, Jinli Li, Bo Cao, Michael S. DeMott, Yihua Sun, Ying Chen, Zixin Deng, Peter C. Dedon, Delin You
Publikováno v:
Biomolecules, Vol 10, Iss 11, p 1491 (2020)
DNA phosphorothioate (PT) modification is a novel modification that occurs on the DNA backbone, which refers to a non-bridging phosphate oxygen replaced by sulfur. This exclusive DNA modification widely distributes in bacteria but has not been found
Externí odkaz:
https://doaj.org/article/7f2fd515143944b891b9b02cddcde066
Autor:
Leticia Pollo-Oliveira, Roland Klassen, Nick Davis, Akif Ciftci, Jo Marie Bacusmo, Maria Martinelli, Michael S. DeMott, Thomas J. Begley, Peter C. Dedon, Raffael Schaffrath, Valérie de Crécy-Lagard
Publikováno v:
Biomolecules, Vol 10, Iss 2, p 322 (2020)
Modifications found in the Anticodon Stem Loop (ASL) of tRNAs play important roles in regulating translational speed and accuracy. Threonylcarbamoyl adenosine (t6A37) and 5-methoxycarbonyl methyl-2-thiouridine (mcm5s2U34) are critical ASL modificatio
Externí odkaz:
https://doaj.org/article/90c9417bfa2d491abf840ab456cc3ab7
Autor:
Axel Guilbaud, Farzan Ghanegolmohammadi, Yijun Wang, Jiapeng Leng, Alexander Kreymerman, Jacqueline Gamboa Varela, Jessica Garbern, Hannah Elwell, Fang Cao, Elisabeth M. Ricci-Blair, Cui Liang, Seetharamsingh Balamkundu, Charles Vidoudez, Michael S. DeMott, Kenneth Bedi, Kenneth B. Margulies, David A. Bennett, Abraham A. Palmer, Amanda Barkley-Levenson, Richard T. Lee, Peter C. Dedon
SummaryDNA damage causes genomic instability underlying many human diseases. Traditional approaches to DNA damage analysis provide minimal insights into the spectrum of disease-driving DNA lesions and the mechanisms causing imbalances in damage forma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b269d8b153361d65013d8e0789ecc787
https://doi.org/10.1101/2022.11.28.518087
https://doi.org/10.1101/2022.11.28.518087
Autor:
Kayla Borland, Lili Liu, Gregor Ammann, Stefanie Kellner, Shane R. Byrne, Bo Cao, Paria Asadi Atoi, Roland Brecheisen, Qinghua Zhang, Michael S. DeMott, Matthias Heiss, Yasemin Yoluç, Peter C. Dedon, Steffen Kaiser, Tim Gehrke, Felix Hagelskamp
Publikováno v:
Angewandte Chemie. 133:24078-24086
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::78d12b11ff0d0c7608d4b1991d89b8bf
https://doi.org/10.1002/ange.202106215
https://doi.org/10.1002/ange.202106215
Autor:
Peter C. Dedon, Matthias Heiss, Qinghua Zhang, Shane R. Byrne, Michael S. DeMott, Lili Liu, Kayla Borland, Yasemin Yoluç, Paria Asadi Atoi, Tim Gehrke, Roland Brecheisen, Steffen Kaiser, Felix Hagelskamp, Bo Cao, Gregor Ammann, Stefanie Kellner
Publikováno v:
Angewandte Chemie (International Ed. in English)
In this report, we perform structure validation of recently reported RNA phosphorothioate (PT) modifications, a new set of epitranscriptome marks found in bacteria and eukaryotes including humans. By comparing synthetic PT‐containing diribonucleoti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0618974c60550185e2b9f66cd3e960c9
http://europepmc.org/articles/PMC8597057
http://europepmc.org/articles/PMC8597057
Autor:
Michael S. DeMott, Daniel Yim, Sabrina M. Huber, Duanduan Ma, Jo Marie Bacusmo, Peter C. Dedon, Bo Cao, Jennifer Hu, Jieliang Zhou, Sidney Vermeulen, Thomas J. Begley, Valérie de Crécy-Lagard, Nick Davis, Stuart S. Levine
Publikováno v:
Nature biotechnology
Current next-generation RNA-sequencing (RNA-seq) methods do not provide accurate quantification of small RNAs within a sample, due to sequence-dependent biases in capture, ligation and amplification during library preparation. We present a method, ab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93b6fb9afeeb2882c471145b651bf46e
https://doi.org/10.1038/s41587-021-00874-y
https://doi.org/10.1038/s41587-021-00874-y
Autor:
Michael S. DeMott, Bo Cao, Lili Liu, Lianrong Wang, Chen Gu, Jieliang Zhou, Xiaolin Wu, Peter C. Dedon, Qinghua Zhang, Delin You, Hang Wu
Publikováno v:
Nucleic Acids Research
DNA damage and epigenetic marks are well established to have profound influences on genome stability and cell phenotype, yet there are few technologies to obtain high-resolution genomic maps of the many types of chemical modifications of DNA. Here we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5ef2b7f87acf702616b81bb0f86d675
http://europepmc.org/articles/PMC7337925
http://europepmc.org/articles/PMC7337925
Autor:
Somchart Maenpuen, Narumon Thongdee, Erin G. Prestwich, Skorn Mongkolsuk, Wenhe Zhong, Abbas El Sahili, Sopapan Atichartpongkul, Yok Hian Chionh, Megan E. McBee, Julien Lescar, Chong Wai Liew, Juthamas Jaroensuk, Pimchai Chaiyen, Yee Hwa Wong, Peter C. Dedon, Michael S. DeMott, Mayuree Fuangthong, Qianhui Nah
Publikováno v:
RNA. 25:1481-1496
The tRNA (m1G37) methyltransferase TrmD catalyzes m1G formation at position 37 in many tRNA isoacceptors and is essential in most bacteria, which positions it as a target for antibiotic development. In spite of its crucial role, little is known about
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::10d0f9510160f0ccf682b4a455242e3b
https://doi.org/10.1261/rna.066746.118
https://doi.org/10.1261/rna.066746.118
Autor:
Jinli Li, Michael S. DeMott, Zixin Deng, Lingxin Kong, Peter C. Dedon, Yihua Sun, Ying Chen, Delin You, Tao Zheng, Bo Cao, Sucheng Zhu
Publikováno v:
Biomolecules, Vol 10, Iss 1491, p 1491 (2020)
Biomolecules
Volume 10
Issue 11
Biomolecules
Volume 10
Issue 11
DNA phosphorothioate (PT) modification is a novel modification that occurs on the DNA backbone, which refers to a non-bridging phosphate oxygen replaced by sulfur. This exclusive DNA modification widely distributes in bacteria but has not been found
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17f2705e7737a3f5fcdc18719d7ec418
https://www.mdpi.com/2218-273X/10/11/1491
https://www.mdpi.com/2218-273X/10/11/1491