Zobrazeno 1 - 10
of 184
pro vyhledávání: '"Michael Rusch"'
Autor:
Yasmine A. Valentin-Vega, Yong-Dong Wang, Matthew Parker, Deanna M. Patmore, Anderson Kanagaraj, Jennifer Moore, Michael Rusch, David Finkelstein, David W. Ellison, Richard J. Gilbertson, Jinghui Zhang, Hong Joo Kim, J. Paul Taylor
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-3 (2024)
Externí odkaz:
https://doaj.org/article/2e6b3753624f496fa1688dfcc00ce983
Autor:
Xinran Dong, Liang Ding, Andrew Thrasher, Xinge Wang, Jingjing Liu, Qingfei Pan, Jordan Rash, Yogesh Dhungana, Xu Yang, Isabel Risch, Yuxin Li, Lei Yan, Michael Rusch, Clay McLeod, Koon-Kiu Yan, Junmin Peng, Hongbo Chi, Jinghui Zhang, Jiyang Yu
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-10 (2023)
Abstract Many signaling and other genes known as “hidden” drivers may not be genetically or epigenetically altered or differentially expressed at the mRNA or protein levels, but, rather, drive a phenotype such as tumorigenesis via post-translatio
Externí odkaz:
https://doaj.org/article/14c0f151bd884b528e374cdf295c69fb
Autor:
Ji Wen, Michael Rusch, Samuel W. Brady, Ying Shao, Michael N. Edmonson, Timothy I. Shaw, Brent B. Powers, Liqing Tian, John Easton, Charles G. Mullighan, Tanja Gruber, David Ellison, Jinghui Zhang
Publikováno v:
BMC Cancer, Vol 21, Iss 1, Pp 1-14 (2021)
Abstract Background RNA editing leads to post-transcriptional variation in protein sequences and has important biological implications. We sought to elucidate the landscape of RNA editing events across pediatric cancers. Methods Using RNA-Seq data ma
Externí odkaz:
https://doaj.org/article/ee45d5cced7c45b7b5b564ed8ad29fba
Autor:
Samuel W. Brady, Yanling Liu, Xiaotu Ma, Alexander M. Gout, Kohei Hagiwara, Xin Zhou, Jian Wang, Michael Macias, Xiaolong Chen, John Easton, Heather L. Mulder, Michael Rusch, Lu Wang, Joy Nakitandwe, Shaohua Lei, Eric M. Davis, Arlene Naranjo, Cheng Cheng, John M. Maris, James R. Downing, Nai-Kong V. Cheung, Michael D. Hogarty, Michael A. Dyer, Jinghui Zhang
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
Genomic analysis of neuroblastoma has revealed important disease etiology. In this study, the authors assembled whole genome, exome and transcriptome data from over 700 neuroblastomas and identified molecular signatures correlated with age, and rare,
Externí odkaz:
https://doaj.org/article/6d1ddb168abf4a2ea4dc3f42ec5b32a2
Autor:
Michael Rusch, Joy Nakitandwe, Sheila Shurtleff, Scott Newman, Zhaojie Zhang, Michael N. Edmonson, Matthew Parker, Yuannian Jiao, Xiaotu Ma, Yanling Liu, Jiali Gu, Michael F. Walsh, Jared Becksfort, Andrew Thrasher, Yongjin Li, James McMurry, Erin Hedlund, Aman Patel, John Easton, Donald Yergeau, Bhavin Vadodaria, Ruth G. Tatevossian, Susana Raimondi, Dale Hedges, Xiang Chen, Kohei Hagiwara, Rose McGee, Giles W. Robinson, Jeffery M. Klco, Tanja A. Gruber, David W. Ellison, James R Downing, Jinghui Zhang
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
Clinical oncology is rapidly adopting next-generation sequencing technology for nucleotide variant and indel detection. Here the authors present a three-platform approach (whole-genome, whole-exome, and whole-transcriptome) in pediatric patients for
Externí odkaz:
https://doaj.org/article/70098f25f1d6428b99342a75e0d3ce05
Autor:
Yasmine A. Valentin-Vega, Yong-Dong Wang, Matthew Parker, Deanna M. Patmore, Anderson Kanagaraj, Jennifer Moore, Michael Rusch, David Finkelstein, David W. Ellison, Richard J. Gilbertson, Jinghui Zhang, Hong Joo Kim, J. Paul Taylor
Publikováno v:
Scientific Reports, Vol 6, Iss 1, Pp 1-16 (2016)
Abstract DDX3X is a DEAD-box RNA helicase that has been implicated in multiple aspects of RNA metabolism including translation initiation and the assembly of stress granules (SGs). Recent genomic studies have reported recurrent DDX3X mutations in num
Externí odkaz:
https://doaj.org/article/740bec2ec2be4c35aafbd83048a74f4c
Autor:
Xiang Chen, Armita Bahrami, Alberto Pappo, John Easton, James Dalton, Erin Hedlund, David Ellison, Sheila Shurtleff, Gang Wu, Lei Wei, Matthew Parker, Michael Rusch, Panduka Nagahawatte, Jianrong Wu, Shenghua Mao, Kristy Boggs, Heather Mulder, Donald Yergeau, Charles Lu, Li Ding, Michael Edmonson, Chunxu Qu, Jianmin Wang, Yongjin Li, Fariba Navid, Najat C. Daw, Elaine R. Mardis, Richard K. Wilson, James R. Downing, Jinghui Zhang, Michael A. Dyer
Publikováno v:
Cell Reports, Vol 7, Iss 1, Pp 104-112 (2014)
Pediatric osteosarcoma is characterized by multiple somatic chromosomal lesions, including structural variations (SVs) and copy number alterations (CNAs). To define the landscape of somatic mutations in pediatric osteosarcoma, we performed whole-geno
Externí odkaz:
https://doaj.org/article/40f55a27461a4869b9e264b8b60dc172
Autor:
Masayuki Umeda, Jing Ma, Tamara Westover, Yonghui Ni, Guangchun Song, Jamie Maciaszek, Michael Rusch, Delaram Rahbarinia, Scott Foy, Benjamin Huang, Michael Walsh, Priyadarshini Kumar, Yanling Liu, Yiping Fan, Gang Wu, Sharyn Baker, Xiaotu Ma, Lu Wang, Jeffrey rubnitz, Stanley Pounds, Jeffery Klco
Recent studies on pediatric acute myeloid leukemia (pAML) have revealed pediatric-specific driver alterations, many of which are underrepresented in the current classification schemas. To comprehensively define the genomic landscape of pAML, we syste
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bece17ee87b60b08af53b3588ae52bf4
https://doi.org/10.21203/rs.3.rs-2925426/v1
https://doi.org/10.21203/rs.3.rs-2925426/v1
Autor:
Jeffery M. Klco, Xiaotu Ma, Soheil Meshinchi, Jeffrey E. Rubnitz, Jinghui Zhang, M. Madan Babu, Stanley Pounds, Charles G. Mullighan, James R. Downing, Todd A. Alonzo, Yi-Cheng Wang, Hiroto Inaba, Gang Wu, Michael Rusch, Delaram Rahbarinia, Evadnie Rampersaud, Jason R. Myers, Jonathan Miller, Ryan Hiltenbrand, Ilaria Iacobucci, Evan Parganas, Jenny L. Smith, Rhonda E. Ries, Yen-Chun Liu, Marcus B. Valentine, Virginia Valentine, Huiyun Wu, John Easton, Bengsheng Ju, Amanda R. Leonti, Andrew B. Kleist, Jamie L. Maciaszek, Scott G. Foy, Quang Tran, Pandurang Kolekar, Xiaolong Chen, Yanling Liu, Liqing Tian, Guangchun Song, Michael P. Walsh, Melvin E. Thomas, Juan M. Barajas, Sherif Abdelhamed, Tamara Westover, Kohei Hagiwara, Benjamin J. Huang, Jing Ma, Masayuki Umeda
The genetics of relapsed pediatric acute myeloid leukemia (AML) has yet to be comprehensively defined. Here, we present the spectrum of genomic alterations in 136 relapsed pediatric AMLs. We identified recurrent exon 13 tandem duplications (TD) in up
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c6c15e8269161afbfa878da7ad418de
https://doi.org/10.1158/2643-3230.c.6550658.v1
https://doi.org/10.1158/2643-3230.c.6550658.v1
Autor:
Jeffery M. Klco, Xiaotu Ma, Soheil Meshinchi, Jeffrey E. Rubnitz, Jinghui Zhang, M. Madan Babu, Stanley Pounds, Charles G. Mullighan, James R. Downing, Todd A. Alonzo, Yi-Cheng Wang, Hiroto Inaba, Gang Wu, Michael Rusch, Delaram Rahbarinia, Evadnie Rampersaud, Jason R. Myers, Jonathan Miller, Ryan Hiltenbrand, Ilaria Iacobucci, Evan Parganas, Jenny L. Smith, Rhonda E. Ries, Yen-Chun Liu, Marcus B. Valentine, Virginia Valentine, Huiyun Wu, John Easton, Bengsheng Ju, Amanda R. Leonti, Andrew B. Kleist, Jamie L. Maciaszek, Scott G. Foy, Quang Tran, Pandurang Kolekar, Xiaolong Chen, Yanling Liu, Liqing Tian, Guangchun Song, Michael P. Walsh, Melvin E. Thomas, Juan M. Barajas, Sherif Abdelhamed, Tamara Westover, Kohei Hagiwara, Benjamin J. Huang, Jing Ma, Masayuki Umeda
Supplementary Data from Integrated Genomic Analysis Identifies UBTF Tandem Duplications as a Recurrent Lesion in Pediatric Acute Myeloid Leukemia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61856b4d04dd5ad8020d0a10bd090d6c
https://doi.org/10.1158/2643-3230.22544486
https://doi.org/10.1158/2643-3230.22544486