Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Michael Riffle"'
Autor:
Ray Sajulga, Caleb Easterly, Michael Riffle, Bart Mesuere, Thilo Muth, Subina Mehta, Praveen Kumar, James Johnson, Bjoern Andreas Gruening, Henning Schiebenhoefer, Carolin A Kolmeder, Stephan Fuchs, Brook L Nunn, Joel Rudney, Timothy J Griffin, Pratik D Jagtap
Publikováno v:
PLoS ONE, Vol 15, Iss 11, p e0241503 (2020)
To gain a thorough appreciation of microbiome dynamics, researchers characterize the functional relevance of expressed microbial genes or proteins. This can be accomplished through metaproteomics, which characterizes the protein expression of microbi
Externí odkaz:
https://doaj.org/article/9da73087023c4018882f7a4da3170b7c
Autor:
Kimberly K. Fong, Alex Zelter, Beth Graczyk, Jill M. Hoyt, Michael Riffle, Richard Johnson, Michael J. MacCoss, Trisha N. Davis
Publikováno v:
Biology Open, Vol 7, Iss 10 (2018)
Phosphorylation regulates yeast spindle pole body (SPB) duplication and separation and likely regulates microtubule nucleation. We report a phosphoproteomic analysis using tandem mass spectrometry of enriched Saccharomyces cerevisiae SPBs for two cel
Externí odkaz:
https://doaj.org/article/b8f2f9f6e7e44e6f82c0185927ccd913
Autor:
Jae ook Kim, Alex Zelter, Neil T Umbreit, Athena Bollozos, Michael Riffle, Richard Johnson, Michael J MacCoss, Charles L Asbury, Trisha N Davis
Publikováno v:
eLife, Vol 6 (2017)
Strong kinetochore-microtubule attachments are essential for faithful segregation of sister chromatids during mitosis. The Dam1 and Ndc80 complexes are the main microtubule binding components of the Saccharomyces cerevisiae kinetochore. Cooperation b
Externí odkaz:
https://doaj.org/article/5f0cbcb043664709adff91b73532d04c
Autor:
Michael Riffle, Damon H. May, Emma Timmins-Schiffman, Molly P. Mikan, Daniel Jaschob, William Stafford Noble, Brook L. Nunn
Publikováno v:
Proteomes, Vol 6, Iss 1, p 2 (2017)
Metaproteomics is the characterization of all proteins being expressed by a community of organisms in a complex biological sample at a single point in time. Applications of metaproteomics range from the comparative analysis of environmental samples (
Externí odkaz:
https://doaj.org/article/733a3bfbd965478c82001c41550163dd
Autor:
Lars Malmström, Michael Riffle, Charlie E M Strauss, Dylan Chivian, Trisha N Davis, Richard Bonneau, David Baker
Publikováno v:
PLoS Biology, Vol 5, Iss 4, p e76 (2007)
Saccharomyces cerevisiae is one of the best-studied model organisms, yet the three-dimensional structure and molecular function of many yeast proteins remain unknown. Yeast proteins were parsed into 14,934 domains, and those lacking sequence similari
Externí odkaz:
https://doaj.org/article/3d2903ae1917477193ee6bb42bfab50a
Autor:
Michael R. Hoopmann, David D. Shteynberg, Alex Zelter, Michael Riffle, Andrew S. Lyon, David A. Agard, Qing Luan, Brad J. Nolen, Michael J. MacCoss, Trisha N. Davis, Robert L. Moritz
Publikováno v:
Journal of Proteome Research. 22:647-655
Autor:
Michael Riffle, Michael R. Hoopmann, Daniel Jaschob, Guo Zhong, Robert L. Moritz, Michael J. MacCoss, Trisha N. Davis, Nina Isoherranen, Alex Zelter
Publikováno v:
Analytical Chemistry. 94:3501-3509
Drugs are often metabolized to reactive intermediates that form protein adducts. Adducts can inhibit protein activity, elicit immune responses, and cause life-threatening adverse drug reactions. The masses of reactive metabolites are frequently unkno
Autor:
Katherine H. Reiter, Alex Zelter, Maria K. Janowska, Michael Riffle, Nicholas Shulman, Brendan X. MacLean, Kaipo Tamura, Matthew C. Chambers, Michael J. MacCoss, Trisha N. Davis, Miklos Guttman, Peter S. Brzovic, Rachel E. Klevit
Publikováno v:
Structure (London, England : 1993). 30(9)
RING-between-RING (RBR) E3 ligases mediate ubiquitin transfer through an obligate E3-ubiquitin thioester intermediate prior to substrate ubiquitination. Although RBRs share a conserved catalytic module, substrate recruitment mechanisms remain enigmat
Autor:
H. Rodger Harvey, Michael Riffle, Dasha Krayushkina, Brook L. Nunn, Emma Timmins-Schiffman, Damon May, Jessica F. Faux
Publikováno v:
Scientific Data, Vol 6, Iss 1, Pp 1-6 (2019)
Scientific Data
Scientific Data
The heterotrophic marine bacterium, Ruegeria pomeroyi, was experimentally cultured under environmentally realistic carbon conditions and with a tracer-level addition of 13C-labeled leucine to track bacterial protein biosynthesis through growth phases
Autor:
Rachel L. Flores, Zachary E. Peterson, Alex Zelter, Michael Riffle, Charles L. Asbury, Trisha N. Davis
Publikováno v:
The Journal of cell biology. 221(5)
Accurate mitosis requires kinetochores to make persistent, load-bearing attachments to dynamic microtubule tips, thereby coupling chromosome movements to tip growth and shortening. This tip-coupling behavior depends on the conserved Ndc80 complex and