Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Michael Rade"'
Autor:
Michael Rade, Markus Kreuz, Angelika Borkowetz, Ulrich Sommer, Conny Blumert, Susanne Füssel, Catharina Bertram, Dennis Löffler, Dominik J. Otto, Livia A. Wöller, Carolin Schimmelpfennig, Ulrike Köhl, Ann-Cathrin Gottschling, Pia Hönscheid, Gustavo B. Baretton, Manfred Wirth, Christian Thomas, Friedemann Horn, Kristin Reiche
Publikováno v:
Molecular Medicine, Vol 30, Iss 1, Pp 1-20 (2024)
Abstract Background Clinical manifestation of prostate cancer (PCa) is highly variable. Aggressive tumors require radical treatment while clinically non-significant ones may be suitable for active surveillance. We previously developed the prognostic
Externí odkaz:
https://doaj.org/article/c464d6da04a84fa9b2ebac3773083177
Autor:
Michael Rade, Sebastian Böhlen, Vanessa Neuhaus, Dennis Löffler, Conny Blumert, Maximilian Merz, Ulrike Köhl, Susann Dehmel, Katherina Sewald, Kristin Reiche
Publikováno v:
Genome Biology, Vol 24, Iss 1, Pp 1-26 (2023)
Abstract Background The coordinated transcriptional regulation of activated T-cells is based on a complex dynamic behavior of signaling networks. Given an external stimulus, T-cell gene expression is characterized by impulse and sustained patterns ov
Externí odkaz:
https://doaj.org/article/ffa3005e33b34cc29a0db10630ff1cf6
Autor:
Carolin Schimmelpfennig, Michael Rade, Susanne Füssel, Dennis Löffler, Conny Blumert, Catharina Bertram, Angelika Borkowetz, Dominik J. Otto, Sven-Holger Puppel, Pia Hönscheid, Ulrich Sommer, Gustavo B. Baretton, Ulrike Köhl, Manfred Wirth, Christian Thomas, Friedemann Horn, Markus Kreuz, Kristin Reiche
Publikováno v:
BMC Cancer, Vol 23, Iss 1, Pp 1-20 (2023)
Abstract Background Prostate cancer (PCa) is one of the most prevalent cancers worldwide. The clinical manifestations and molecular characteristics of PCa are highly variable. Aggressive types require radical treatment, whereas indolent ones may be s
Externí odkaz:
https://doaj.org/article/33f9e042a8f748879f7f4908f10f205d
Autor:
Susann Haehnel, Michael Rade, Nicole Kaiser, Kristin Reiche, Andreas Horn, Dennis Loeffler, Conny Blumert, Felicitas Rapp, Friedemann Horn, Juergen Meixensberger, Christof Renner, Wolf Mueller, Frank Gaunitz, Ingo Bechmann, Karsten Winter
Publikováno v:
FEBS Open Bio, Vol 12, Iss 2, Pp 480-493 (2022)
One of the major challenges in cancer research is finding models that closely resemble tumors within patients. Human tissue slice cultures are a promising approach to provide a model of the patient's tumor biology ex vivo. Recently, it was shown that
Externí odkaz:
https://doaj.org/article/e8d3e8b47318451f91056afeb3b27eb9
Autor:
Henry Loeffler-Wirth, Michael Rade, Arsen Arakelyan, Markus Kreuz, Markus Loeffler, Ulrike Koehl, Kristin Reiche, Hans Binder
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Anti-CD19 CAR-T cell immunotherapy is a hopeful treatment option for patients with B cell lymphomas, however it copes with partly severe adverse effects like neurotoxicity. Single-cell resolved molecular data sets in combination with clinical paramet
Externí odkaz:
https://doaj.org/article/b3cdc0fde7454a6a808af79a74d06e62
Autor:
Susann Haehnel, Kristin Reiche, Dennis Loeffler, Andreas Horn, Conny Blumert, Sven-Holger Puppel, Nicole Kaiser, Felicitas Rapp, Michael Rade, Friedemann Horn, Juergen Meixensberger, Ingo Bechmann, Frank Gaunitz, Karsten Winter
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-15 (2019)
Abstract Cancer research requires models closely resembling the tumor in the patient. Human tissue cultures can overcome interspecies limitations of animal models or the loss of tissue architecture in in vitro models. However, analysis of tissue slic
Externí odkaz:
https://doaj.org/article/806433dc29524087a1454b735a1e3e16
Autor:
Maik Friedrich, Karolin Wiedemann, Kristin Reiche, Sven-Holger Puppel, Gabriele Pfeifer, Ivonne Zipfel, Stefanie Binder, Ulrike Köhl, Gerd A. Müller, Kurt Engeland, Achim Aigner, Susanne Füssel, Michael Fröhner, Claudia Peitzsch, Anna Dubrovska, Michael Rade, Sabina Christ, Stephan Schreiber, Jörg Hackermüller, Jörg Lehmann, Marieta I. Toma, Michael H. Muders, Ulrich Sommer, Gustavo B. Baretton, Manfred Wirth, Friedemann Horn
Publikováno v:
Cancers, Vol 12, Iss 5, p 1122 (2020)
In search of new biomarkers suitable for the diagnosis and treatment of prostate cancer, genome-wide transcriptome sequencing was carried out with tissue specimens from 40 prostate cancer (PCa) and 8 benign prostate hyperplasia patients. We identifie
Externí odkaz:
https://doaj.org/article/38b05cd247be42b0aab2a78f192acbbe
Autor:
Susann Haehnel, Michael Rade, Nicole Kaiser, Kristin Reiche, Andreas Horn, Dennis Loeffler, Conny Blumert, Felicitas Rapp, Friedemann Horn, Juergen Meixensberger, Christof Renner, Wolf Mueller, Frank Gaunitz, Ingo Bechmann, Karsten Winter
Publikováno v:
FEBS Open Bio
FEBS Open Bio, Vol 12, Iss 2, Pp 480-493 (2022)
FEBS Open Bio 12(2), 480-493 (2022). doi:10.1002/2211-5463.13353
FEBS Open Bio, Vol 12, Iss 2, Pp 480-493 (2022)
FEBS Open Bio 12(2), 480-493 (2022). doi:10.1002/2211-5463.13353
One of the major challenges in cancer research is finding models that closely resemble tumors within patients. Human tissue slice cultures are a promising approach to provide a model of the patient's tumor biology ex vivo. Recently, it was shown that
Autor:
Sonia Guedan, Maik Luu, Delphine Ammar, Paula Barbao, Chiara Bonini, Philippe Bousso, Christian J Buchholz, Monica Casucci, Biagio De Angelis, Emmanuel Donnadieu, David Espie, Beatrice Greco, Richard Groen, Johannes B Huppa, Chahrazade Kantari-Mimoun, Bruno Laugel, Mary Mantock, Janet L Markman, Emma Morris, Concetta Quintarelli, Michael Rade, Kristin Reiche, Alba Rodriguez-Garcia, Juan Roberto Rodriguez-Madoz, Eliana Ruggiero, Maria Themeli, Michael Hudecek, Ibtissam Marchiq
Publikováno v:
Journal for Immunotherapy of Cancer
Journal for Immunotherapy of Cancer, 2022, 10 (5), pp.e003487. ⟨10.1136/jitc-2021-003487⟩
Guedan, S, Luu, M, Ammar, D, Barbao, P, Bonini, C, Bousso, P, Buchholz, C J, Casucci, M, De Angelis, B, Donnadieu, E, Espie, D, Greco, B, Groen, R, Huppa, J B, Kantari-Mimoun, C, Laugel, B, Mantock, M, Markman, J L, Morris, E, Quintarelli, C, Rade, M, Reiche, K, Rodriguez-Garcia, A, Rodriguez-Madoz, J R, Ruggiero, E, Themeli, M, Hudecek, M & Marchiq, I 2022, ' Time 2EVOLVE : predicting efficacy of engineered T-cells-how far is the bench from the bedside? ', Journal for Immunotherapy of Cancer, vol. 10, no. 5 . https://doi.org/10.1136/jitc-2021-003487
Journal for Immunotherapy of Cancer, 2022, 10 (5), pp.e003487. ⟨10.1136/jitc-2021-003487⟩
Guedan, S, Luu, M, Ammar, D, Barbao, P, Bonini, C, Bousso, P, Buchholz, C J, Casucci, M, De Angelis, B, Donnadieu, E, Espie, D, Greco, B, Groen, R, Huppa, J B, Kantari-Mimoun, C, Laugel, B, Mantock, M, Markman, J L, Morris, E, Quintarelli, C, Rade, M, Reiche, K, Rodriguez-Garcia, A, Rodriguez-Madoz, J R, Ruggiero, E, Themeli, M, Hudecek, M & Marchiq, I 2022, ' Time 2EVOLVE : predicting efficacy of engineered T-cells-how far is the bench from the bedside? ', Journal for Immunotherapy of Cancer, vol. 10, no. 5 . https://doi.org/10.1136/jitc-2021-003487
International audience; Immunotherapy with gene engineered CAR and TCR transgenic T-cells is a transformative treatment in cancer medicine. There is a rich pipeline with target antigens and sophisticated technologies that will enable establishing thi
Autor:
Zahir Basrai, Manuel Celedon, Nathalie Dieujuste, Julianne Himstreet, Jonathan Hoffman, Cassidy Pfaff, Jonie Hsiao, Robert Malstrom, Jason Smith, Michael Radeos, Terri Jorgenson, Melissa Christopher, Comilla Sasson
Publikováno v:
Western Journal of Emergency Medicine, Vol 25, Iss 4, Pp 465-469 (2024)
Introduction: The seemingly inexorable rise of opioid-related overdose deaths despite the reduced number of COVID-19 pandemic deaths demands novel responses and partnerships in our public health system’s response. Addiction medicine is practiced in
Externí odkaz:
https://doaj.org/article/513674ed10894f08a627b0d17921e7e0