Zobrazeno 1 - 3
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pro vyhledávání: '"Michael R. Wyler"'
Autor:
Tamara Caspary, Kathryn V. Anderson, Michael R. Wyler, Evan H. Feinberg, Jonathan T. Eggenschwiler, Andrew S. Rakeman, Jeffrey D. Lee, María J. García-García, Danwei Huangfu, John R. Timmer, Heather L. Alcorn
Publikováno v:
Proceedings of the National Academy of Sciences. 102:5913-5919
Many aspects of the genetic control of mammalian embryogenesis cannot be extrapolated from other animals. Taking a forward genetic approach, we have induced recessive mutations by treatment of mice with ethylnitrosourea and have identified 43 mutatio
Autor:
Tamara Caspary, Michael R. Wyler, Kathryn V. Anderson, Heather L. Alcorn, Danwei Huangfu, Andrew S. Rakeman, María J. García-García, Jonathan T. Eggenschwiler
Publikováno v:
Current Biology. 12:1628-1632
Precise patterning of cell types along the dorsal-ventral axis of the spinal cord is essential to establish functional neural circuits [1]. In order to prove the feasibility of studying a single biological process through random mutagenesis in the mo
Autor:
Michael R, Wyler, Deborah H, Smith, Eftihia, Cayanis, Udo, Többen, Nathalie, Aulner, Thomas, Mayer
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 486
To understand signaling pathways in mammalian cells, cell-based assays are relatively new and extremely powerful tools. We have developed a battery of phenotypic assays to study signaling; two of them are described in detail in this chapter. A subset