Zobrazeno 1 - 10
of 52
pro vyhledávání: '"Michael R. Volkert"'
Autor:
Michael R. Volkert, David J. Crowley
Publikováno v:
Frontiers in Neuroscience, Vol 14 (2020)
Parkinson’s disease, diabetic retinopathy, hyperoxia induced retinopathy, and neuronal damage resulting from ischemia are among the notable neurodegenerative diseases in which oxidative stress occurs shortly before the onset of neurodegeneration. A
Externí odkaz:
https://doaj.org/article/c7d705a6c06047cd8531b2fe518b39f0
Autor:
Sushma Vishwakarma, Rishikesh Kumar Gupta, Saumya Jakati, Mudit Tyagi, Rajeev Reddy Pappuru, Keith Reddig, Gregory Hendricks, Michael R. Volkert, Hemant Khanna, Jay Chhablani, Inderjeet Kaur
Publikováno v:
Antioxidants, Vol 9, Iss 8, p 654 (2020)
Fibrocellular membrane or epiretinal membrane (ERM) forms on the surface of the inner limiting membrane (ILM) in the inner retina and alters the structure and function of the retina. ERM formation is frequently observed in ocular inflammatory conditi
Externí odkaz:
https://doaj.org/article/c7cbeecc49824078afdb4345deeed08d
Autor:
Bhubanananda Sahu, Laura Moreno Leon, Wei Zhang, Michael R. Volkert, Hemant Khanna, Nikita Puranik, Ramesh Periasamy
Publikováno v:
Investigative Ophthalmology & Visual Science
Purpose Oxidative stress is a major factor underlying many neurodegenerative diseases. However, antioxidant therapy has had mixed results, possibly because of its indiscriminate activity. The purpose of our study was to determine if the human OXR1 (h
Autor:
David J. Crowley, Michael R. Volkert
Publikováno v:
Frontiers in Neuroscience, Vol 14 (2020)
Frontiers in Neuroscience
Frontiers in Neuroscience
Parkinson’s disease, diabetic retinopathy, hyperoxia induced retinopathy, and neuronal damage resulting from ischemia are among the notable neurodegenerative diseases in which oxidative stress occurs shortly before the onset of neurodegeneration. A
Autor:
Lijian Yu, Michael R. Volkert
Publikováno v:
Nucleic Acids Research
Alternative polyadenylation (APA) is conserved in all eukaryotic cells. Selective use of polyadenylation sites appears to be a highly regulated process and contributes to human pathogenesis. In this article we report that the yeast RPB2 gene is alter
Publikováno v:
BMC Molecular Biology
Background Cells respond to numerous internal and external stresses, such as heat, cold, oxidative stress, DNA damage, and osmotic pressure changes. In most cases, the primary response to stress is transcriptional induction of genes that assist the c
Autor:
Carla Esposito, Valentina Rippa, Paolo Landini, Michael R. Volkert, Angela Amoresano, Angela Duilio
Publikováno v:
Journal of Bacteriology. 192:6136-6142
Upon exposure to alkylating agents, Escherichia coli increases expression of aidB along with three genes ( ada , alkA , and alkB ) that encode DNA repair proteins. While the biological roles of the Ada, AlkA, and AlkB proteins have been defined, desp
Autor:
Jae U. Jung, Mary T. Pickering, Timothy F. Kowalik, Heesoon Chang, Nam Hyuk Cho, Xiaozhen Liang, Michael R. Volkert
Publikováno v:
Journal of Virology. 80:5862-5874
Infected cells recognize viral replication as a DNA damage stress and elicit a DNA damage response that ultimately induces apoptosis as part of host immune surveillance. Here, we demonstrate a novel mechanism where the murine gamma herpesvirus 68 (γ
Autor:
Nathan Elliott, Michael R. Volkert
Publikováno v:
Molecular and Cellular Biology. 24:3180-3187
Reactive oxygen species (ROS) are critical molecules produced as a consequence of aerobic respiration. It is essential for cells to control the production and activity of such molecules in order to protect the genome and regulate cellular processes s
Publikováno v:
Molecular Microbiology. 28:15-24
The transposon Tn5 ble gene and the Escherichia coli alkylation-inducible aidC locus are co-operatively involved in the resistance to the anti-cancer drug and DNA-cleaving agent bleomycin and enhance fitness of bacteria in the absence of the drug. In