Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Michael R. Tanen"'
Autor:
David E. Moller, Emanuel Zycband, Michael R. Tanen, Joel Berger, Chhabi Biswas, David J. Figueroa, John Woods, Christopher P. Austin
Publikováno v:
Brain Research. 975:10-21
The peroxisome proliferator-activated receptors (PPARs), PPARdelta, PPARgamma and PPARalpha, comprise a subclass of the supergene family of nuclear receptors. As such they are ligand-regulated transcription factors whose major effects are mediated by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77f5c0711d519d23e9aa97cc2f1b756a
https://doi.org/10.1016/s0006-8993(03)02515-0
https://doi.org/10.1016/s0006-8993(03)02515-0
Autor:
John Ventre, Mona Parikh, Thomas W. Doebber, Bruce A. Johnson, Ann Petro, Gaochao Zhou, Joel Berger, Bei B. Zhang, Linda J. Kelly, Neelam Sharma, Michael R. Tanen, Alan D. Adams, Chhabi Biswas, Ralph T. Mosley, Richard S. Surwit, Alex Elbrecht, G. Marie Thompson, David E. Moller, Karen L. MacNaul, Karen Richards
Publikováno v:
Molecular Endocrinology. 17:662-676
Antidiabetic thiazolidinediones (TZDs) and non-TZD compounds have been shown to serve as agonists of the peroxisome proliferator-activated receptor gamma (PPARgamma). Here, we report the identification and characterization of a novel non-TZD selectiv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc313c36fc3c5d00f1f4f35a62207650
https://doi.org/10.1210/me.2002-0217
https://doi.org/10.1210/me.2002-0217
Autor:
Bei Zhang, Gregory D. Berger, Chhabi Biswas, Robert W. Marquis, Joel Berger, Richard L. Tolman, Conrad Santini, Roy G. Smith, Ying Li, Gaochou Zhou, Margaret Wu, John Ventre, Nancy S. Hayes, David E. Moller, Thomas W. Doebber, Michael R. Tanen, Soumya P. Sahoo, Alex Elbrecht, Mark D. Leibowitz, Catherine A. Cullinan, Ralph T. Mosley
Publikováno v:
Journal of Biological Chemistry. 274:6718-6725
The peroxisome proliferator-activated receptors (PPARs) include three receptor subtypes encoded by separate genes: PPARalpha, PPARdelta, and PPARgamma. PPARgamma has been implicated as a mediator of adipocyte differentiation and the mechanism by whic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d759ee2bf37a009fb5d374059ed9f683
https://doi.org/10.1074/jbc.274.10.6718
https://doi.org/10.1074/jbc.274.10.6718
Publikováno v:
Journal of Biological Chemistry. 270:10601-10611
We investigated the molecular mechanisms underlying the transcriptional silencing and the hormone-induced activation of target genes by thyroid hormone receptor beta (TR-beta). We developed a cell-free transcription system containing HeLa cell nuclea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64a9828fe5251b370eb5194e0c34f267
https://doi.org/10.1074/jbc.270.18.10601
https://doi.org/10.1074/jbc.270.18.10601
Autor:
Joel Berger, Michael R. Tanen, Alex Elbrecht, David E. Moller, Samuel D. Wright, Rolf Thieringer, Anne Hermanowski-Vosatka
Publikováno v:
The Journal of biological chemistry. 276(16)
Peroxisome proliferator-activated receptor-gamma (PPARgamma) has been shown to play an important role in the regulation of expression of a subclass of adipocyte genes and to serve as the molecular target of the thiazolidinedione (TZD) and certain non
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::851d7ab4188f0324133bd407f9465482
https://pubmed.ncbi.nlm.nih.gov/11278270
https://pubmed.ncbi.nlm.nih.gov/11278270
Publikováno v:
Molecular endocrinology (Baltimore, Md.). 11(6)
The nuclear hormone receptors belonging to the steroid/thyroid/retinoid receptor superfamily are ligand-inducible transcription factors. These receptors modulate transcription of specific cellular genes, either positively or negatively, by interactin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f09edec9fb70972f6bf702eb36bf0d7
https://pubmed.ncbi.nlm.nih.gov/9171239
https://pubmed.ncbi.nlm.nih.gov/9171239
Publikováno v:
Molecular and cellular biology. 16(5)
Unliganded thyroid hormone receptor (TR) functions as a transcriptional repressor of genes bearing thyroid hormone response elements in their promoters. Binding of hormonal ligand to the receptor releases the transcriptional silencing and leads to ge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::024d5e07eb8eded085273f56c6ac1c4f
https://pubmed.ncbi.nlm.nih.gov/8628257
https://pubmed.ncbi.nlm.nih.gov/8628257