Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Michael R. Scherer"'
Autor:
Heather F Pidcoke, Wilfred Delacruz, Maryanne C Herzig, Beverly S Schaffer, Sahar T Leazer, Chriselda G Fedyk, Robbie K Montogomery, Nicolas J Prat, Bijaya K Parida, James K Aden, Michael R Scherer, Robert L Reddick, Robert E Shade, Andrew P Cap
Publikováno v:
PLoS ONE, Vol 17, Iss 12, p e0279694 (2022)
A perfluorocarbon (PFC) investigated for treatment of traumatic brain injury (TBI) delivers oxygen to support brain function, but causes transient thrombocytopenia. TBI can cause acute inflammation with resulting thrombocytopenia; an interaction betw
Externí odkaz:
https://doaj.org/article/ecc3faad40b14eefb38de77adbf4c278
Autor:
Morten Zaar, Chriselda G Fedyk, Heather F Pidcoke, Michael R Scherer, Kathy L Ryan, Caroline A Rickards, Carmen Hinojosa-Laborde, Victor A Convertino, Andrew P Cap
Publikováno v:
PLoS ONE, Vol 9, Iss 12, p e116174 (2014)
Central hypovolemia elevates hemostatic activity which is essential for preventing exsanguination after trauma, but platelet activation to central hypovolemia has not been described. We hypothesized that central hypovolemia induced by lower body nega
Externí odkaz:
https://doaj.org/article/fee438bd1c7d4745aaa8d2a332d9c94b
Autor:
Michael R. Scherer, Jeffrey D. Keesee, Andrew P. Cap, Jacob Chen, Daniel N. Darlington, Avi Benov, Robbie K. Montgomery, Xiaowu Wu, Bin Liu
Publikováno v:
British Journal of Haematology. 179:802-810
The in vitro haemostatic functions of fresh whole blood (FWB) are well preserved after cold storage. This study aimed to determine whether platelets derived from FWB and stored whole blood (SWB) contribute to clot formation in tissue injury after tra
Publikováno v:
Innate Immunity. 21:140-150
Burn induces an immunopathological response involving multiple immune cell types that includes γδ T-cells. Nonetheless, the role of γδ T-cells at the wound site after burn is not clearly defined. Wild type and γδ T-cell receptor deficient (δ T
Autor:
Andrew P. Cap, Heather F. Pidcoke, Alex G. Mora, Armando C Rodriguez, Ron S. Bryant, Heather L. Reddy, Chriselda G. Fedyk, Michael R. Scherer, Robbie K. Montgomery, James K. Aden, Kristin M. Reddoch, Raymond P. Goodrich, Steve J McFaul, John A. Jones, Bijaya K. Parida, Anand K. Ramasubramanian, Krystal K. Valdez-Delgado
Publikováno v:
Transfusion. 53:137S-149S
BACKGROUND: Whole blood (WB) has been used in combat since World War I as it is readily available and replaces every element of shed blood. Component therapy has become standard; however, recent military successes with WB resuscitation have revived t
Autor:
Martin G. Schwacha, Michael R. Scherer, Chriselda G. Fedyk, Daniel L. Dent, Michael A. Dubick, Andrew P. Cap, Marc A. Salhanick, Heather F. Pidcoke, Valere G. Sams
Publikováno v:
Shock (Augusta, Ga.). 46(2)
PURPOSE The autotransfusion of unwashed (or unprocessed) shed hemothorax blood (USHB) in trauma patients is widely assumed to be beneficial; however, the inflammatory potential of shed pleural blood has not been thoroughly studied. Since previous stu
Autor:
John B. Holcomb, Chriselda G. Fedyk, Michael R. Scherer, Ángel V. Delgado, Charles E. Wade, Bijan S. Kheirabadi, Michael A. Dubick, Andrew P. Cap, Daniel N. Darlington, Anthony E. Pusateri
Publikováno v:
Journal of Trauma: Injury, Infection & Critical Care. 71:1152-1163
This study evaluates the effect of hemodilution by various common resuscitation fluids, and the efficacy of activated recombinant factor VII (rFVIIa) on coagulation parameters in human blood in vitro.Samples from normal healthy volunteers (n = 9) wer
Autor:
Michael R. Scherer, Michael A. Dubick, Bijan S. Kheirabadi, Chriselda G. Fedyk, John B. Holcomb, Ángel V. Delgado, Anthony E. Pusateri
Publikováno v:
Journal of Trauma: Injury, Infection & Critical Care. 63:1079-1086
Recombinant activated factor VII (rFVIIa) is currently administered off-label to control diffuse coagulopathic bleeding of patients with traumatic injuries. These patients are often cold, acidotic, and coagulopathic upon arrival and each responds dif
Autor:
Michael R. Scherer, Allen P. Burke, Jennifer Wojtaszczyk, Kathy L. Ryan, John B. Holcomb, Anthony E. Pusateri, Ángel V. Delgado, John M. Uscilowicz, Joseph M Macaitis, Heather Currier, Suzanne Christensen, Rodolpho DeGuzman, Douglas S Cortez, Jason Bliss, Harold G. Klemcke
Publikováno v:
The Journal of Trauma: Injury, Infection, and Critical Care. 59:155-161
BACKGROUND Previous experiments with diverse pig models to evaluate the ability of rFVIIa to reduce hemorrhage have provided divergent results. The current study was conducted to address concerns related to previous work by using larger sample sizes,
Autor:
Michael R. Scherer, Gary J. Mihalik
Publikováno v:
Psychiatric Clinics of North America. 23:285-296
The many parties, which now possess a role in behavioral health care services, are each concerned about the quality of these services. The concept of accreditation of MBHOs differs little from the board certification and licensure mechanisms used to