Lithium chloride dilution as a new method of cardiac output determination in the dog: effect of lithium chloride dosage on serum lithium concentration

Autor: Michael R. O'Grady, J. P. Woods, Wayne N. McDonell, D. J. Mason

Publikováno v: Veterinary anaesthesia and analgesia. 28(2)

We have previously demonstrated excellent agreement in the dog between thermodilution (TD) and lithium chloride dilution (LCD) as measures of CO, with an intraclass correlation of 0.989. LCD results in an accumulation of lithium (Li) in the body, whi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::078c29a5aa35a27c71e6c9fc8a2c2a39
https://pubmed.ncbi.nlm.nih.gov/28404351

Evaluation of 10 genes encoding cardiac proteins in Doberman Pinschers with dilated cardiomyopathy

Autor: W. Glen Pyle, John F. Dawson, M. Lynne O'Sullivan, Michael R. O'Grady

Publikováno v: American Journal of Veterinary Research. 72:932-939

Objective—To identify a causative mutation for dilated cardiomyopathy (DCM) in Doberman Pinschers by sequencing the coding regions of 10 cardiac genes known to be associated with familial DCM in humans. Animals—5 Doberman Pinschers with DCM and c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c0788fece7bc3acb01cccbd5578abaa
https://doi.org/10.2460/ajvr.72.7.932

Plasma Big Endothelin-1, Atrial Natriuretic Peptide, Aldosterone, and Norepinephrine Concentrations in Normal Doberman Pinschers and Doberman Pinschers with Dilated Cardiomyopathy

Autor: Sandra L. Minors, Michael R. O'Grady, M. Lynne O'Sullivan

Publikováno v: Journal of Veterinary Internal Medicine. 21:92-99

Background: Dilated Cardiomyopathy (DCM) results in progressive myocardial and circulatory dysfunction causing activation of a number of neurohormonal systems, including the endothelin (ET) system, which is only beginning to be described in clinical

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac4ef14fc77d4bc3010e9534f9c17af5
https://doi.org/10.1111/j.1939-1676.2007.tb02933.x

Systemic effects of topical and subconjunctival ophthalmic atropine in the horse

Autor: Michael R. O'Grady, Bernhard M. Spiess, Peter J Pascoe, Melanie M. Williams

Publikováno v: Veterinary Ophthalmology. 3:193-199

OBJECTIVE: To identify any systemic effects of topical and subconjunctival administration of atropine sulfate in the horse. Animals studied Six mature grade horses were treated hourly in one eye with topical ophthalmic atropine drops for 24 h. Five h

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d79aba038aaa9653f3910d86ef4c0c41
https://doi.org/10.1046/j.1463-5224.2000.00118.x

Efficacy of pimobendan in the prevention of congestive heart failure or sudden death in doberman pinschers with preclinical dilated cardiomyopathy (the PROTECT study)

Autor: M. Patteson, Adrian Boswood, Sonya G. Gordon, Ruth Willis, J. Loureiro, P. Watson, Geoff Culshaw, M. L. O'Sullivan, Sarah Smith, Mark A. Oyama, Joanna Dukes-McEwan, Amara H. Estrada, Michael R. O'Grady, L Braz-Ruivo, Anne French, Nuala Summerfield

Publikováno v: Summerfield, N J, Boswood, A, O'Grady, M R, Gordon, S G, Dukes-McEwan, J, Oyama, M A, Smith, S, Patteson, M, French, A T, Culshaw, G J, Braz-Ruivo, L, Estrada, A, O'Sullivan, M L, Loureiro, J, Willis, R & Watson, P 2012, ' Efficacy of Pimobendan in the Prevention of Congestive Heart Failure or Sudden Death in Doberman Pinschers with Preclinical Dilated Cardiomyopathy (The PROTECT Study) ', Journal of Veterinary Internal Medicine, vol. 26, no. 6, pp. 1337-49 . https://doi.org/10.1111/j.1939-1676.2012.01026.x
Summerfield, N J, Boswood, A, O'Grady, M R, Gordon, S G, Dukes-McEwan, J, Oyama, M A, Smith, S, Patteson, M, French, A T, Culshaw, G J, Braz-Ruivo, L, Estrada, A, O'Sullivan, M L, Loureiro, J, Willis, R & Watson, P 2013, ' Efficacy of Pimobendan in the prevention of congestive heart failure or sudden death in Doberman Pinschers with preclinical dilated cardiomyopathy (The PROTECT Study) ', Kleintierpraxis, vol. 58, no. 4, pp. 169-186 . https://doi.org/10.1111/j.1939-1676.2012.01026.x
Journal of Veterinary Internal Medicine

Background: The benefit of pimobendan in delaying the progression of preclinical dilated cardiomyopathy (DCM) in Dobermans is not reported.\ud \ud Hypothesis: That chronic oral administration of pimobendan to Dobermans with preclinical DCM will delay

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b6c3a8b703381566cacbda4f61f2e30
https://eprints.gla.ac.uk/78495/1/78495.pdf