Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Michael R. McClurg"'
Autor:
Marcus F. Boehm, Lin Zhang, Lin Zhi, Michael R. McClurg, Elain Berger, Murriel Wagoner, Dale E. Mais, Carla M. Suto, Peter J. A. Davies, Richard A. Heyman, Alex M. Nadzan
Publikováno v:
Journal of Medicinal Chemistry. 38:3146-3155
Structural modifications of the retinoid X receptor (RXR) selective compound 4-[1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydro-2- naphthyl)ethenyl]benzoic acid (LGD1069), which is currently in phase I/IIA clinical trials for cancer and dermatological in
Autor:
Alex M. Nadzan, Marcus F. Boehm, Lin. Zhang, Beth Ann Badea, Lin Zhi, Steven K. White, Dale E. Mais, Elaine Berger, Carla M. Suto, Michael R. McClurg, Peter J.A. Davies, Richard A. Heyman
Publikováno v:
European Journal of Medicinal Chemistry. 30:519s-533s
Autor:
David J. Mangelsdorf, Richard A. Heyman, Marcus F. Boehm, Michael R. McClurg, Jonathan J. Hebert, Charles Pathirana, Steven K. White, David T. Winn, Mark E. Goldman
Publikováno v:
Journal of Medicinal Chemistry. 37:408-414
all-trans-Retinoic acid is known to bind to the retinoic acid receptors (RARs) resulting in an increase in their transcriptional activity. In contrast, recently identified 9-cis-retinoic acid (9-cis-RA), which is an additional endogenous RA isomer, i
Publikováno v:
Journal of Neuroimmunology. 28:209-217
The effects of beta-endorphin (beta-E) and contained peptides were investigated for their ability to regulate Staphylococcus aureus (SAC)-induced immunoglobulin secretion by human B lymphocytes. Co-culture of beta-E with SAC-stimulated peripheral blo